Methods and compositions for inducing an immune response to EGFRvIII
The present invention relates to methods of inducing a T-cell response against a EGFRvIII in a subject. These method comprise administering to a subject a composition which expresses at least one immunogenic polypeptide, the amino acid sequence of which comprise a plurality of EGFRvIII polypeptide sequences, the sequence of which each comprise EEKKGNYV (SEQ ID NO: 3), and/or administering the polypeptide itself.
ADURO BIOTECH, INC. (Berkeley, CA); PROVIDENCE HEALTH & SERVICES--OREGON (Portland, OR)
Lauer, Peter M. and Bahjat, Keith, "Methods and compositions for inducing an immune response to EGFRvIII" (2013). Technology Transfer - Patents. 29.