Allogeneic autophagosome-enriched composition for the treatment of disease
A composition, comprising: an enriched population of autophagosomes derived from a non-small cell lung carcinoma cell line, and wherein the enriched population of autophagosomes includes: one or more toll-like receptor agonists; one or more tumor antigens; and one or more damage-associated molecular pattern molecules. In this way, an off-the-shelf vaccine may be available to be administered in order to stimulate a targeted immune response in patients bearing different tumor types.
Allergy & Immunology
UbiVac, LLC (Portland, OR); Providence Health & Services-Oregon (Portland, OR)
Hilton, Traci; Aung, Sandra; van de Ven, Rieneke; Paustian, Christopher; Moudgil, Tarsem; Dubay, Christopher; Twitty, Christopher; Hu, Hong-Ming; and Fox, Bernard A., "Allogeneic autophagosome-enriched composition for the treatment of disease" (2013). Technology Transfer - Patents. 16.