Single cell analyses demonstrate that a heme - GATA1 feedback loop regulates red cell differentiation.
Erythropoiesis is the complex, dynamic, and tightly-regulated process that generates all mature red blood cells. To understand this process, we mapped the developmental trajectories of progenitors from wildtype, erythropoietin-treated and
Institute for Systems Biology
Doty, Raymond T; Yan, Xiaowei; Lausted, Christopher; Munday, Adam D; Yang, Zhantao; Yi, Danielle; Jabbari, Neda; Liu, Li; Keel, Siobán B; Tian, Qiang; and Abkowitz, Janis L, "Single cell analyses demonstrate that a heme - GATA1 feedback loop regulates red cell differentiation." (2018). Articles, Abstracts, and Reports. 923.