Phase II Feasibility Study of a Weight Loss Intervention in Female Breast and Colorectal Cancer Survivors (SWOG S1008).
Document Type
Article
Publication Date
10-1-2018
Abstract
OBJECTIVE: This study aimed to test the feasibility of a 12-month weight loss intervention using telephone-based counseling plus community-situated physical activity (PA) in female breast cancer (BC) and colorectal cancer (CRC) survivors.
METHODS: This multisite cooperative group study enrolled sedentary, female, postmenopausal BC and CRC survivors with BMI ≥ 25 kg/m
RESULTS: Among 25 BC survivors, median baseline BMI was 37.2 (range: 27.7-54.6), accrual occurred in 10 months, 60% and 28% met diet and exercise goals, 80% provided 12-month measures, and average weight loss was 7.6% (95% CI: -3.9%, 19.2%). Among 23 CRC survivors, median BMI was 31.8 (range: 26.4-48.7), accrual occurred in 24 months, 61% and 17% met diet and exercise goals, 87% provided measures, and average weight loss was 2.5% (95% CI: -8.2%, 13.3%).
CONCLUSIONS: It is feasible to recruit and retain BC survivors in a cooperative group diet and PA weight loss trial. BC survivors achieved clinically meaningful weight loss but did not meet a priori adherence goals. In CRC survivors, recruitment was more difficult, and the intervention was less effective.
Clinical Institute
Cancer
Clinical Institute
Women & Children
Department
Oncology
Recommended Citation
Greenlee, Heather; Lew, Danika L; Hershman, Dawn L; Newman, Vicky A; Hansen, Lisa; Hartman, Sheri J; Korner, Judith; Shi, Zaixing; Sardo Molmenti, Christine L; Sayegh, Antoine; Fehrenbacher, Lou; Lo, Shelly; Klemp, Jennifer; Rinn, Kristine; Robertson, John M; Unger, Joseph; Gralow, Julie; Albain, Kathy; Krouse, Robert; and Fabian, Carol, "Phase II Feasibility Study of a Weight Loss Intervention in Female Breast and Colorectal Cancer Survivors (SWOG S1008)." (2018). Articles, Abstracts, and Reports. 811.
https://digitalcommons.providence.org/publications/811
