A water-soluble alternative to simethicone for gastrointestinal endoscopy: Results of a clinical trial.
American journal of infection control
During endoscopy, simethicone defoaming agents are commonly used to improve visualization, but they leave residues and impact drying. This clinical trial involved patients undergoing colonoscopy procedures with substantial bubbles that impeded mucosal wall visibility. As an alternative to simethicone, investigators evaluated a water-soluble, ginger-based gastrointestinal supplement (GI-Ease) that did not contain sugars, thickeners, or binding agents. In 112/114 cases (98%), bubbles were reduced sufficiently to allow visualization of the gastrointestinal tract, with no adverse events.
Mallard, Teri S; Roswell, Sandra S; Sylvester, Evan P; Ofstead, Cori L; Scanlan, James M; Brandabur, John J; and Ramakrishnan, Amarnath V, "A water-soluble alternative to simethicone for gastrointestinal endoscopy: Results of a clinical trial." (2023). Articles, Abstracts, and Reports. 7222.