TP73 DNA methylation and upregulation of ΔNp73 are associated with an adverse prognosis in breast cancer
Breast; Breast Neoplasms; Carcinoma, Ductal, Breast; CpG Islands; DNA Methylation; Disease-Free Survival; Female; Humans; Immunohistochemistry; Prognosis; Protein Isoforms; Tumor Protein p73
AIM: Accumulated evidence suggests that aberrant methylation of the
RESULTS: We observed that the methylation of diverse CpG islands of
CONCLUSIONS: Our findings suggest that high expression of ΔNp73 could be used to determine the aggressiveness of IDCs and could be incorporated in the pathologist's report.
Journal of clinical pathology
Gomez, Laura C; Sottile, Mayra L; Guerrero-Gimenez, Martin E; Zoppino, Felipe C M; Redondo, Analia L; Gago, Francisco E; Orozco, Javier I; Tello, Olga M; Roqué, Maria; Nadin, Silvina B; Marzese, Diego M; and Vargas-Roig, Laura M, "TP73 DNA methylation and upregulation of ΔNp73 are associated with an adverse prognosis in breast cancer" (2018). All Publications. 67.