Title

TP73 DNA methylation and upregulation of ΔNp73 are associated with an adverse prognosis in breast cancer

Document Type

Article

Publication Date

1-1-2018

Keywords

Breast; Breast Neoplasms; Carcinoma, Ductal, Breast; CpG Islands; DNA Methylation; Disease-Free Survival; Female; Humans; Immunohistochemistry; Prognosis; Protein Isoforms; Tumor Protein p73

Abstract

AIM: Accumulated evidence suggests that aberrant methylation of the

METHODS:

RESULTS: We observed that the methylation of diverse CpG islands of

CONCLUSIONS: Our findings suggest that high expression of ΔNp73 could be used to determine the aggressiveness of IDCs and could be incorporated in the pathologist's report.

Clinical Institute

Cancer

Department

Oncology

Volume

71

Issue

1

First Page

52

Last Page

58

PubMed ID

28743687

Journal Title

Journal of clinical pathology

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