Phase 2 of extracellular RNA communication consortium charts next-generation approaches for extracellular RNA research.

Authors

Bogdan Mateescu
Jennifer C Jones
Roger P Alexander
Eric Alsop
Ji Yeong An
Mohammad Asghari
Alex Boomgarden
Laura Bouchareychas
Alfonso Cayota
Hsueh-Chia Chang
Al Charest
Daniel T Chiu
Robert J Coffey
Saumya Das
Peter De Hoff
Andrew deMello
Crislyn D'Souza-Schorey
David Elashoff
Kiarash R Eliato
Jeffrey L Franklin
David J Galas
Mark B Gerstein
Ionita H Ghiran
David B Go
Stephen Gould
Tristan R Grogan
James N Higginbotham
Florian Hladik
Tony Jun Huang
Xiaoye Huo
Elizabeth Hutchins
Dennis K Jeppesen
Tijana Jovanovic-Talisman
Betty Y S Kim
Sung Kim
Kyoung-Mee Kim
Yong Kim
Robert R Kitchen
Vaughan Knouse
Emily L LaPlante
Carlito B Lebrilla
L James Lee
Kathleen M Lennon
Guoping Li
Feng Li
Tieyi Li
Tao Liu
Zirui Liu
Adam L Maddox
Kyle McCarthy
Bessie Meechoovet
Nalin Maniya
Yingchao Meng
Aleksandar Milosavljevic
Byoung-Hoon Min
Amber Morey
Martin Ng
John Nolan
Getulio P De Oliveira Junior
Michael E Paulaitis
Tuan Anh Phu
Robert L Raffai
Eduardo Reátegui
Matthew E Roth
David A Routenberg
Joel Rozowsky
Joseph Rufo
Satyajyoti Senapati
Sigal Shachar
Himani Sharma
Anil K Sood
Stavros Stavrakis
Alessandra Stürchler
Muneesh Tewari
Juan P Tosar
Alexander K Tucker-Schwartz
Andrey Turchinovich
Nedyalka Valkov
Kendall Van Keuren-Jensen
Kasey C Vickers
Lucia Vojtech
Wyatt N Vreeland
Ceming Wang
Kai Wang, Institute for Systems Biology, Seattle, WA 98109, USA.
ZeYu Wang
Joshua A Welsh
Kenneth W Witwer
David T W Wong
Jianping Xia
Ya-Hong Xie
Kaichun Yang
Mikołaj P Zaborowski
Chenguang Zhang
Qin Zhang
Angela M Zivkovic
Louise C Laurent

Document Type

Article

Publication Date

8-19-2022

Publication Title

iScience

Keywords

washington; isb; seattle

Abstract

The extracellular RNA communication consortium (ERCC) is an NIH-funded program aiming to promote the development of new technologies, resources, and knowledge about exRNAs and their carriers. After Phase 1 (2013-2018), Phase 2 of the program (ERCC2, 2019-2023) aims to fill critical gaps in knowledge and technology to enable rigorous and reproducible methods for separation and characterization of both bulk populations of exRNA carriers and single EVs. ERCC2 investigators are also developing new bioinformatic pipelines to promote data integration through the exRNA atlas database. ERCC2 has established several Working Groups (Resource Sharing, Reagent Development, Data Analysis and Coordination, Technology Development, nomenclature, and Scientific Outreach) to promote collaboration between ERCC2 members and the broader scientific community. We expect that ERCC2's current and future achievements will significantly improve our understanding of exRNA biology and the development of accurate and efficient exRNA-based diagnostic, prognostic, and theranostic biomarker assays.

Department

Institute for Systems Biology

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