Operative Treatment of Severe Scoliosis in Symptomatic Adults: Multicenter Assessment of Outcomes and Complications With Minimum 2-Year Follow-up.
washington; seattle; swedish neuroscience; Adult spinal deformity; Complications; Coronal imbalance/malalignment; Health-related quality of life; Outcomes; Sagittal imbalance/malalignment; Scoliosis; Spine surgery
BACKGROUND: Few reports focus on adults with severe scoliosis.
OBJECTIVE: To report surgical outcomes and complications for adults with severe scoliosis.
METHODS: A multicenter, retrospective review was performed on operatively treated adults with severe scoliosis (minimum coronal Cobb: thoracic [TH] ≥ 75°, thoracolumbar [TL] ≥ 50°, lumbar [L] ≥ 50°).
RESULTS: Of 178 consecutive patients, 146 (82%; TH = 8, TL = 88, L = 50) achieved minimum 2-yr follow-up (mean age = 53.9 ± 13.2 yr, 92% women). Operative details included posterior-only (58%), 3-column osteotomy (14%), iliac fixation (72%), and mean posterior fusion = 13.2 ± 3.7 levels. Global coronal alignment (3.8 to 2.8 cm, P = .001) and maximum coronal Cobb improved significantly (P ≤.020): TH (84º to 57º; correction = 32%), TL (67º to 35º; correction = 48%), L (61º to 29º; correction = 53%). Sagittal alignment improved significantly (P < .001), most notably for L: C7-sagittal vertical axis 6.7 to 2.5 cm, pelvic incidence-lumbar lordosis mismatch 18º to 3º. Health-related quality-of-life (HRQL) improved significantly (P < .001), most notably for L: Oswestry Disability Index (44.4 ± 20.5 to 26.1 ± 18.3), Short Form-36 Physical Component Summary (30.2 ± 10.8 to 39.9 ± 9.8), and Scoliosis Research Society-22r Total (2.9 ± 0.7 to 3.8 ± 0.7). Minimal clinically important difference and substantial clinical benefit thresholds were achieved in 36% to 75% and 29% to 51%, respectively. Ninety-four (64%) patients had ≥1 complication (total = 191, 92 minor/99 major, most common = rod fracture [13.0%]). Fifty-seven reoperations were performed in 37 (25.3%) patients, with most common indications deep wound infection (11) and rod fracture (10).
CONCLUSION: Although results demonstrated high rates of complications, operative treatment of adults with severe scoliosis was associated with significant improvements in mean HRQL outcome measures for the study cohort at minimum 2-yr follow-up.
Neurosciences (Brain & Spine)
Orthopedics & Sports Medicine
Buell, Thomas J; Smith, Justin S; Shaffrey, Christopher I; Kim, Han Jo; Klineberg, Eric O; Lafage, Virginie; Lafage, Renaud; Protopsaltis, Themistocles S; Passias, Peter G; Mundis, Gregory M; Eastlack, Robert K; Deviren, Vedat; Kelly, Michael P; Daniels, Alan H; Gum, Jeff L; Soroceanu, Alex; Hamilton, D Kojo; Gupta, Munish C; Burton, Douglas C; Hostin, Richard A; Kebaish, Khaled M; Hart, Robert A; Schwab, Frank J; Bess, Shay; and Ames, Christopher P, "Operative Treatment of Severe Scoliosis in Symptomatic Adults: Multicenter Assessment of Outcomes and Complications With Minimum 2-Year Follow-up." (2021). Articles, Abstracts, and Reports. 5422.