Effects of a topical botanically-enriched salve on cutaneous oxygenation.

Document Type

Article

Publication Date

2-1-2019

Publication Title

Journal of wound care

Keywords

Administration, Cutaneous; Cross-Over Studies; Diabetes Mellitus, Type 2; Diabetic Foot; Double-Blind Method; Female; Humans; Male; Middle Aged; Ointments; Oxygen; Plant Extracts; Skin; Treatment Outcome; Wound Healing

Abstract

OBJECTIVE: There is a medical need to evaluate new treatments that may improve wound healing. This study aimed to determine if Original Healing Salve (OHS, Puremedy, Inc.) a topical, botanically-enriched salve (BES), changes distal leg tissue oxygenation in people with type 2 diabetes.

METHOD: A randomised, controlled, crossover, double-blinded clinical trial comparing changes in cutaneous oxygen delivery (mean TcPO

RESULTS: A total of 16 participants were recruited. Analysis of the primary outcome demonstrated no statistically significant difference in TcPO

CONCLUSION: These findings support consideration of topical treatments containing botanical ingredients to increase cutaneous oxygen delivery in the lower extremity in patients with type 2 diabetes.

Clinical Institute

Kidney & Diabetes

Department

Endocrinology

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