The NEALS primary lateral sclerosis registry.
Amyotroph Lateral Scler Frontotemporal Degener
oregon; portland; Adult; Amyotrophic Lateral Sclerosis; Humans; Motor Neuron Disease; Neurodegenerative Diseases; Registries; Retrospective Studies
BACKGROUND AND OBJECTIVE: Primary lateral sclerosis (PLS) is a neurodegenerative disease characterized by progressive upper motor neuron dysfunction. Because PLS patients represent only 1 to 4% of patients with adult motor neuron diseases, there is limited information about the disease's natural history. The objective of this study was to establish a large multicenter retrospective longitudinal registry of PLS patients seen at Northeast ALS Consortium (NEALS) sites to better characterize the natural progression of PLS.
Neurosciences (Brain & Spine)
Paganoni, Sabrina; De Marchi, Fabiola; Chan, James; Thrower, Sara K; Staff, Nathan P; Datta, Neil; Kisanuki, Yaz Y; Drory, Vivian; Fournier, Christina; Pioro, Erik P; Goutman, Stephen A; Atassi, Nazem; NEALS PLS Registry Study Group; Jeon, Maryangel; Caldwell, Sarah; Mcdonough, Timothy; Gentile, Caroline; Liu, Jianing; Turner, Michelle; Denny, Carol; Felice, Kevin; Green, Misty; Scarberry, Stephanie; Abu-Saleh, Saad; Nefussy, Beatrice; Hastings, Debbie; Kim, Sangri; Swihart, Blake; Arcila-Londono, Ximena; Newman, Daniel S; Silverman, Michael; Genge, Angela; Salmon, Kristiana; Elman, Lauren; Mccluskey, Leo; Almasy, Kelly; Gotkine, Marc; Goslin, Kimberly; Cummings, Arlena; Edwards, Eli K; Rivner, Michael; Bouchard, Kristy; Quarles, Brandy; Kwan, Justin; Jaffa, Matthew; Baloh, Robert; Allred, Peggy; Walk, David; Maiser, Samuel; Manousakis, Georgios; Ferment, Valerie; Fernandes, J Americo M; Thaisetthawatkul, Pariwat; Heimes, Deborah; Phillips, Melissa; Sams, Laura; Kahler, Melissa; Corcoran, Alecia; Larriviere, Daniel G; Chotto, Sadie; and Juba, Gracy, "The NEALS primary lateral sclerosis registry." (2020). Articles, Abstracts, and Reports. 5264.