The assessment of sarcopenia using psoas muscle thickness per height is not predictive of post-operative complications in IBD.

Document Type

Article

Publication Date

8-3-2021

Publication Title

Scandinavian journal of gastroenterology

Keywords

california; newport beach; hoag

Abstract

BACKGROUND: Sarcopenia is associated with postoperative complications in inflammatory bowel disease. It has most commonly been defined using the skeletal muscle index, computed after analysis of cross-sectional muscle area at L3. Psoas muscle thickness normalized to height (PMTH), which is easier to derive, is a potential surrogate of SMI and sarcopenia in patients with cirrhosis and chronic pancreatitis. We investigate whether sarcopenia defined by PMTH has utility in predicting post-operative outcomes in patients with inflammatory bowel disease.

METHODS: We performed a retrospective study of adults undergoing IBD-related surgery from 2009 to 2019 at two hospitals. Sarcopenia was defined by sex-specific PMTH at the umbilicus on cross-sectional imaging using a 50

RESULTS: 85 patients with IBD were included. Lower albumin level (OR = 0.52,

CONCLUSIONS: A low status of PMTH was not associated with increased postoperative complications, however hypoalbuminemia and biologic use were. PMTH as a surrogate for sarcopenia requires further study, ideally with prospective studies comparing PMTH with accepted radiographic surrogates for sarcopenia, to determine its role in clinical decision making.

Clinical Institute

Digestive Health

Department

Gastroenterology

Department

Surgery

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