Anticancer activity study of A
Adenosine A3 Receptor Agonists; Animals; Antineoplastic Agents; Apoptosis; Autophagy; Caco-2 Cells; Cell Division; Cell Line, Tumor; Cell Movement; Colorectal Neoplasms; Dose-Response Relationship, Drug; Humans; Liver Neoplasms, Experimental; Male; Prostatic Neoplasms; Reactive Oxygen Species; Signal Transduction; Structure-Activity Relationship
MATERIALS AND METHODS: In the present study was determined the in vitro activity of known 1-3 and newly 4-6 synthesized compounds with high A
KEY FINDINGS: Results show that the anticancer effect is not due to A
SIGNIFICANCE: These results show that the new compound 5 exerts inhibitory effect on cancer cells through differential effect and may serve as a potential anticancer agent.
Institute for Systems Biology
Marucci, Gabriella; Santinelli, Claudia; Buccioni, Michela; Navia, Aleix Martí; Lambertucci, Catia; Zhurina, Anastasia; Yli-Harja, Olli; Volpini, Rosaria; and Kandhavelu, Meenakshisundaram, "Anticancer activity study of A" (2018). Journal Articles and Abstracts. 402.