Anticancer activity study of A

Document Type

Article

Publication Date

7-15-2018

Publication Title

Life sciences

Keywords

Adenosine A3 Receptor Agonists; Animals; Antineoplastic Agents; Apoptosis; Autophagy; Caco-2 Cells; Cell Division; Cell Line, Tumor; Cell Movement; Colorectal Neoplasms; Dose-Response Relationship, Drug; Humans; Liver Neoplasms, Experimental; Male; Prostatic Neoplasms; Reactive Oxygen Species; Signal Transduction; Structure-Activity Relationship

Abstract

AIMS: A

MATERIALS AND METHODS: In the present study was determined the in vitro activity of known 1-3 and newly 4-6 synthesized compounds with high A

KEY FINDINGS: Results show that the anticancer effect is not due to A

SIGNIFICANCE: These results show that the new compound 5 exerts inhibitory effect on cancer cells through differential effect and may serve as a potential anticancer agent.

Clinical Institute

Cancer

Department

Institute for Systems Biology

Department

Oncology

Share

COinS