Kidney Int Rep
Introduction: Patients are often instructed to engage in multiple weekly sessions of exercise to increase physical activity. We aimed to determine whether assignment to a supervised exercise regimen increases overall weekly activity in individuals with chronic kidney disease (CKD).
Methods: We performed a secondary analysis of a pilot randomized 2 × 2 factorial design trial examining the effects of diet and exercise (10%-15% reduction in caloric intake, 3 supervised exercise sessions/wk, combined diet restriction/exercise, and control). Activity was measured as counts detected by accelerometer. Counts data were collected on all days for which an accelerometer was worn at baseline, month 2, and month 4 follow-up. The primary outcome was a relative change from baseline in log-transformed counts/min. Generalized estimating equations were used to compare the primary outcome in individuals in the exercise group and the nonexercise group.
Results: We examined 111 individuals randomized to aerobic exercise or usual activity (n = 48 in the exercise group and n = 44 controls). The mean age was 57 years, 42% were female, and 28% were black. Median overall adherence over all time was 73%. Median (25th, 75th percentile) counts/min over nonsupervised exercise days at months 2 and 4 were 237.5 (6.5, 444.4) for controls and 250.9 (7.7, 529.8) for the exercise group (
Conclusion: Engaging in a supervised exercise program does not increase overall weekly physical activity in individuals with stage 3 to 4 CKD.
Kidney & Diabetes
Pike, Mindy M; Alsouqi, Aseel; Headley, Samuel A E; Tuttle, Katherine; Evans, Elizabeth Elspeth; Milch, Charles M; Moody, Kelsey Anne; Germain, Michael; Stewart, Thomas G; Lipworth, Loren; Himmelfarb, Jonathan; Ikizler, T Alp; and Robinson-Cohen, Cassianne, "Supervised Exercise Intervention and Overall Activity in CKD." (2020). Articles, Abstracts, and Reports. 3600.