Title

The building blocks of successful translation of proteomics to the clinic.

Document Type

Article

Publication Date

2-6-2018

Abstract

Recently, the first two multiplexed tests using selective reaction monitoring (SRM-MS) mass spectrometry have entered clinical practice. Despite different areas of indication, risk stratification in lung cancer and preterm birth, they share multiple steps in their development strategies. Here we review these strategies and their implications for successful translation of biomarkers to clinical practice. We believe that the identification of blood protein panels for the identification of disease phenotypes is now a reproducible and standard (albeit complex) process.

Department

Institute for Systems Biology

Volume

51

First Page

123

Last Page

129

PubMed ID

29427919

Journal Title

Current opinion in biotechnology

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