Both the intratumoral immune and microbial microenvironment are linked to recurrence in human colon cancer: results from a prospective, multicenter nodal ultrastaging trial.
colon cancer; disease free survival; immune cells; immune infiltrate; microbiota
Colon cancer (CC) is the third most common cancer diagnosed in the United States and the incidence has been rising among young adults. We and others have shown a relationship between the immune infiltrate and prognosis, with improved disease-free survival (DFS) being associated with a higher expression of CD8
Noguti, Juliana; Chan, Alfred A; Bandera, Bradley; Brislawn, Colin J; Protic, Mladjan; Sim, Myung S; Jansson, Janet K; Bilchik, Anton J; and Lee, Delphine J, "Both the intratumoral immune and microbial microenvironment are linked to recurrence in human colon cancer: results from a prospective, multicenter nodal ultrastaging trial." (2018). All Publications. 292.