Agonist Abs to TNF Receptor Family Members

Document Type

Abstract

Publication Date

2-28-2020

Publication Title

6th Annual Immuno-Oncology 360°

Abstract

This talk provides a summary of Abs to TNFR family members and their advances to the clinic (OX40, 4-1BB, CD27, GITR and CD40). In particular, OX40 agonists will be the focus of this talk and their effects on targeting T cells within the tumor microenvironment. Optimal dose and scheduling of OX40 agonists will also be reviewed.

Clinical Institute

Cancer

Department

Oncology

Department

Earle A. Chiles Research Institute


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