STAT3 Activation-Induced Fatty Acid Oxidation in CD8

Authors

Chunyan Zhang
Chanyu Yue
Andreas Herrmann
Jieun Song
Colt Egelston
Tianyi Wang
Zhifang Zhang
Wenzhao Li
Heehyoung Lee
Maryam Aftabizadeh
Yi Jia Li
Peter P Lee
Stephen Forman
George Somlo
Peiguo Chu
Laura Kruper
Joanne Mortimer
Dave S B Hoon, Department of Translational Molecular Medicine, John Wayne Cancer Institute (JWCI), Pacific Neuroscience Institute, Saint John's Health Center, Providence Health Systems, Santa Monica, CA, 90404, USAFollow
Wendong Huang
Saul Priceman
Hua Yu

Document Type

Article

Publication Date

11-18-2019

Publication Title

Cell Metab

Abstract

Although obesity is known to be critical for cancer development, how obesity negatively impacts antitumor immune responses remains largely unknown. Here, we show that increased fatty acid oxidation (FAO) driven by activated STAT3 in CD8

Clinical Institute

Cancer

Department

Oncology

Recommended Citation

Zhang, Chunyan; Yue, Chanyu; Herrmann, Andreas; Song, Jieun; Egelston, Colt; Wang, Tianyi; Zhang, Zhifang; Li, Wenzhao; Lee, Heehyoung; Aftabizadeh, Maryam; Li, Yi Jia; Lee, Peter P; Forman, Stephen; Somlo, George; Chu, Peiguo; Kruper, Laura; Mortimer, Joanne; Hoon, Dave S B; Huang, Wendong; Priceman, Saul; and Yu, Hua, "STAT3 Activation-Induced Fatty Acid Oxidation in CD8" (2019). Articles, Abstracts, and Reports. 2559.
https://digitalcommons.providence.org/publications/2559