Cross-classification of physical and affective symptom clusters and 180-day event-free survival in moderate to advanced heart failure.
Document Type
Article
Publication Date
11-18-2019
Publication Title
Heart & lung : the journal of critical care
Keywords
cards
Abstract
BACKGROUND: The relationship between physical and affective symptom clusters in heart failure (HF) is unclear.
OBJECTIVES: To identify associations between physical and affective symptom clusters in HF and to quantify outcomes and determinants of symptom subgroups.
METHODS: This was a secondary analysis of data from two cohort studies among adults with HF. Physical and affective symptom clusters were compared using cross-classification modeling. Cox proportional hazards modeling and multinomial logistic regression were used to identify outcomes and determinants of symptom subgroups, respectively.
RESULTS: In this young, mostly male sample (n = 274), physical and affective symptom clusters were cross-classified in a model with acceptable fit. Three symptom subgroups were identified: congruent-mild (69.3%), incongruent (13.9%), and congruent-severe (16.8%). Compared to the congruent-mild symptom group, the incongruent symptom group had significantly worse 180-day event-free survival.
CONCLUSION: Congruence between physical and affective symptom clusters should be considered when identifying patients at higher risk for poor outcomes.
Clinical Institute
Cardiovascular (Heart)
Department
Cardiology
Department
Center for Cardiovascular Analytics, Research + Data Science (CARDS)
Recommended Citation
Denfeld, Quin E; Bidwell, Julie T; Gelow, Jill M; Mudd, James O; Chien, Christopher V; Hiatt, Shirin O; and Lee, Christopher S, "Cross-classification of physical and affective symptom clusters and 180-day event-free survival in moderate to advanced heart failure." (2019). Articles, Abstracts, and Reports. 2521.
https://digitalcommons.providence.org/publications/2521
