Unresectable hepatoblastoma: current perspectives.

Authors

Angela D Trobaugh-Lotrario, Department of Pediatric Hematology and Oncology, Providence Sacred Heart Children's Hospital, Spokane, WA.
Rebecka L Meyers
Allison F O'Neill
James H Feusner

Document Type

Article

Publication Date

1-1-2017

Publication Title

Hepat Med

Keywords

hepatoblastoma; pediatric; unresectable

Abstract

Although rare, hepatoblastoma is the most common pediatric liver tumor. Complete resection is a critical component for cure; however, most patients will have tumors that are not resected at diagnosis. For these patients, administration of neoadjuvant chemotherapy renders tumors resectable in most patients. For patients whose tumors remain unresectable after chemotherapy, liver transplantation is indicated (in the absence of active unresectable metastatic disease). In patients whose tumors remain unresectable after conventional chemotherapy, interventional techniques may serve as a promising option to reduce tumor size, decrease systemic toxicity, decrease need for liver transplantation, and increase feasibility of tumor resection.

Clinical Institute

Cancer

Clinical Institute

Women & Children

Department

Oncology

Department

Pediatrics

Department

Surgery

Recommended Citation

Trobaugh-Lotrario, Angela D; Meyers, Rebecka L; O'Neill, Allison F; and Feusner, James H, "Unresectable hepatoblastoma: current perspectives." (2017). Articles, Abstracts, and Reports. 2277.
https://digitalcommons.providence.org/publications/2277