Document Type
Article
Publication Date
10-1-2019
Publication Title
Res Pract Thromb Haemost
Abstract
Hemostatic complications are common in patients with ventricular assist devices. The pathophysiologic mechanisms that lead to dysregulated hemostasis involve complex interactions between device surface, sheer stress, and blood flow. These factors lead to various manifestations that require a thorough understanding of the interplay among platelets, coagulation factors, and red cells. In this article, we review the pathophysiology of hematologic complications (bleeding, acquired von Willebrand disease, heparin-induced thrombocytopenia, hemolysis, stroke and pump thrombosis), the clinical manifestations, and the management of each. We summarize the evidence available for management of these entities and provide a pragmatic clinical review.
Clinical Institute
Cardiovascular (Heart)
Department
Cardiology
Recommended Citation
Hilal, Talal; Mudd, James O; and DeLoughery, Thomas G, "Hemostatic complications associated with ventricular assist devices." (2019). Articles, Abstracts, and Reports. 2244.
https://digitalcommons.providence.org/publications/2244
