Vitamin D3 decreases glycolysis and invasiveness, and increases cellular stiffness in breast cancer cells

Document Type

Article

Publication Date

3-1-2018

Publication Title

The Journal of nutritional biochemistry

Keywords

Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Survival; Cholecalciferol; Enzymes; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; Glucose; Glycolysis; Humans; Lactic Acid; MCF-7 Cells; TOR Serine-Threonine Kinases

Abstract

Breast cancer is one of the major causes of death in the USA. Cancer cells, including breast, have high glycolysis rates to meet their energy demands for survival and growth. Vitamin D

Clinical Institute

Cancer

Clinical Institute

Women & Children

Department

Oncology

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