Alzheimers Dement (N Y)
Introduction: Preclinical studies support investigation of focused ultrasound for breakdown of cerebral pathologies in neurodegenerative conditions including Alzheimer's disease (AD) and Parkinson's disease (PD).
Methods: A focused transcranial Doppler device with probes (2 MHz, 520 mW/cm
Results: Of all, 62.5% of patients had one or more improved cognitive scores without data incongruence, 87% had stable or improved fine motor scores, and 87.5% had stable or improved gross motor scores. No adverse events were reported.
Discussion: The safety of focused transcranial Doppler and possible enhancement in patient functioning were suggested by outcome data.
Neurosciences (Brain & Spine)
Nicodemus, Natalie Eleanor; Becerra, Sergio; Kuhn, Taylor P; Packham, Hannah R; Duncan, John; Mahdavi, Kennedy; Iovine, Jessica; Kesari, Santosh; Pereles, Scott; Whitney, Mike; Mamoun, Michael; Franc, Daniel; Bystritsky, Alexander; and Jordan, Sheldon, "Focused transcranial ultrasound for treatment of neurodegenerative dementia." (2019). Articles, Abstracts, and Reports. 1988.