ACG Clinical Guideline: Hereditary Hemochromatosis.

Authors

Kris V Kowdley, Liver Care Network and Organ Care Research, Swedish Medical Center, 1124 Columbia Street, Suite 600, Seattle, WA, 98104, USAFollow
Kyle E Brown
Joseph Ahn
Vinay Sundaram

Document Type

Article

Publication Date

8-1-2019

Publication Title

The American journal of gastroenterology

Abstract

Hereditary hemochromatosis (HH) is one of the most common genetic disorders among persons of northern European descent. There have been recent advances in the diagnosis, management, and treatment of HH. The availability of molecular diagnostic testing for HH has made possible confirmation of the diagnosis for most patients. Several genotype-phenotype correlation studies have clarified the differences in clinical features between patients with the C282Y homozygous genotypes and other HFE mutation patterns. The increasing use of noninvasive tests such as MRI T2* has made quantification of hepatic iron deposition easier and eliminated the need for liver biopsy in most patients. Serum ferritin of

Clinical Institute

Digestive Health

Department

Hematology

Department

Gastroenterology

Recommended Citation

Kowdley, Kris V; Brown, Kyle E; Ahn, Joseph; and Sundaram, Vinay, "ACG Clinical Guideline: Hereditary Hemochromatosis." (2019). Articles, Abstracts, and Reports. 1939.
https://digitalcommons.providence.org/publications/1939