Document Type

Article

Publication Date

7-12-2019

Publication Title

J Immunother Cancer

Abstract

BACKGROUND: CD4

METHODS: TRAPs isolated from tumor cell lines and pleural effusions or ascites of cancer patients were incubated with CD4

RESULTS: Heat shock protein 90α (HSP90α) on the surface of TRAPs from malignant effusions of cancer patients and tumor cell lines stimulated CD4

CONCLUSIONS: HSP90α on the surface of TRAPs programs the immunosuppressive functions of CD4

Clinical Institute

Cancer

Department

Earle A. Chiles Research Institute

Department

Oncology

Included in

Oncology Commons

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