Document Type

Article

Publication Date

1-1-2017

Publication Title

PLoS One

Keywords

Aged; Aged, 80 and over; Atherosclerosis; Cardiovascular Diseases; Case-Control Studies; Female; Glomerular Filtration Rate; Humans; Male; Renal Artery Obstruction; Smoking; Tobacco

Abstract

Cigarette smoking causes cardiovascular disease and is associated with poor kidney function in individuals with diabetes mellitus and primary kidney diseases. However, the association of smoking on patients with atherosclerotic renal artery stenosis has not been studied. The current study utilized data from the Cardiovascular Outcomes in Renal Atherosclerotic Lesions (CORAL, NCT00081731) clinical trial to evaluate the effects of smoking on the risk of cardio-renal events and kidney function in this population. Baseline data showed that smokers (n = 277 out of 931) were significantly younger at enrollment than non-smokers (63.3±9.1 years vs 72.4±7.8 years; p

Clinical Institute

Kidney & Diabetes

Clinical Institute

Cardiovascular (Heart)

Department

Nephrology

Department

Cardiology

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