computational modeling; liver; malaria; omics-technologies; plasmodium; systems biology
Despite global eradication efforts over the past century, malaria remains a devastating public health burden, causing almost half a million deaths annually (WHO, 2016). A detailed understanding of the mechanisms that control malaria infection has been hindered by technical challenges of studying a complex parasite life cycle in multiple hosts. While many interventions targeting the parasite have been implemented, the complex biology of
Institute for Systems Biology
Zuck, Meghan; Austin, Laura S; Danziger, Samuel A; Aitchison, John D; and Kaushansky, Alexis, "The Promise of Systems Biology Approaches for Revealing Host Pathogen Interactions in Malaria." (2017). Articles, Abstracts, and Reports. 1427.