Genome-wide analysis identifies NR4A1 as a key mediator of T cell dysfunction.
T cells become dysfunctional when they encounter self antigens or are exposed to chronic infection or to the tumour microenvironment
Institute for Systems Biology
Liu, Xindong; Wang, Yun; Lu, Huiping; Li, Jing; Yan, Xiaowei; Xiao, Minglu; Hao, Jing; Alekseev, Andrei; Khong, Hiep; Chen, Tenghui; Huang, Rui; Wu, Jin; Zhao, Qiwen; Wu, Qi; Xu, Senlin; Wang, Xiaohu; Jin, Wei; Yu, Shicang; Wang, Yan; Wei, Lai; Wang, Aibo; Zhong, Bo; Ni, Ling; Liu, Xiaolong; Nurieva, Roza; Ye, Lilin; Tian, Qiang; Bian, Xiu-Wu; and Dong, Chen, "Genome-wide analysis identifies NR4A1 as a key mediator of T cell dysfunction." (2019). Articles, Abstracts, and Reports. 1128.