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Submissions from 2021

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Impact of XPO1 mutations on survival outcomes in metastatic non-small cell lung cancer (NSCLC)., Misako Nagasaka, Mohammad Fahad B Asad, Mohammed Najeeb Al Hallak, Md Hafiz Uddin, Ammar Sukari, Yasmine Baca, Joanne Xiu, Dan Magee, Hirva Mamdani, Dipesh Uprety, Chul Kim, Bing Xia, Stephen V Liu, Jorge J Nieva, Gilberto Lopes, Gerold Bepler, Hossein Borghaei, Michael J Demeure, Luis E Raez, Patrick C Ma, Sonam Puri, W Michael Korn, and Asfar S Azmi

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509 A first-in-human phase 1 study of NL-201 in patients with relapsed or refractory cancer, Aung Naing, Brendan Curti, and See full list of authors in comments

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Collagenous Gastritis in Primary Selective IgM Deficiency: Transition to EBV+ Gastric Adenocarcinoma., Tejal Narsai, Houfen Su, David Braxton, and Sudhir Gupta

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Proteogenomic Characterization of Highly Enriched Viable Leukemic Blasts in Acute Myeloid Leukemia: A SWOG Report, Jasmine Naru, John E Godwin, and See full list of authors in comments

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Overall Survival Benefit with Tebentafusp in Metastatic Uveal Melanoma., Paul Nathan, Jessica C Hassel, Piotr Rutkowski, Jean-Francois Baurain, Marcus O Butler, Max Schlaak, Ryan J Sullivan, Sebastian Ochsenreither, Reinhard Dummer, John M Kirkwood, Anthony M Joshua, Joseph J Sacco, Alexander N Shoushtari, Marlana Orloff, Josep M Piulats, Mohammed Milhem, April K S Salama, Brendan Curti, Lev Demidov, Lauris Gastaud, Cornelia Mauch, Melinda Yushak, Richard D Carvajal, Omid Hamid, Shaad E Abdullah, Chris Holland, Howard Goodall, Sophie Piperno-Neumann, and IMCgp100-202 Investigators

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Frequency of Sarcopenia, Sarcopenic Obesity, and Changes in Physical Function in Surgical Oncology Patients Referred for Prehabilitation., An Ngo-Huang, Aliea Herbert, Rhodora C Fontillas, Nathan H Parker, Roan Asumbrado, Naveen Garg, Seyedeh Dibaj, Diane D Liu, Amy H Ng, Ying Guo, Ki Y Shin, Matthew H G Katz, and Eduardo Bruera

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Synthesis and Preclinical Validation of Novel Indole Derivatives as a GPR17 Agonist for Glioblastoma Treatment., Phung Nguyen, Phuong Doan, Tatu Rimpilainen, Saravanan Konda Mani, Akshaya Murugesan, Olli Yli-Harja, Nuno R Candeias, and Meenakshisundaram Kandhavelu

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1665 - QuPath versus InForm: Digital image analysis of multiplex immunofluorescence (mIF) tumor-infiltrating lymphocyte (TIL) outcomes in an immunotherapy clinical trial, Benjamin Nikitin, Brie Chun, Isaac Kim, William L. Redmond, Katherine Sanchez, Zhaoyu Sun, Yaping Wu, and David B Page

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Atezolizumab Plus Chemotherapy for First-Line Treatment of Nonsquamous NSCLC: Results From the Randomized Phase 3 IMpower132 Trial., Makoto Nishio, Fabrice Barlesi, Howard West, Simon Ball, Rodolfo Bordoni, Manuel Cobo, Pascale Dubray Longeras, Jerome Goldschmidt, Silvia Novello, Francisco Orlandi, Rachel E Sanborn, Zsuzsanna Szalai, Grigoriy Ursol, Diana Mendus, Lijia Wang, Xiaohui Wen, Mark McCleland, Tien Hoang, See Phan, and Mark A Socinski

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Safety and efficacy of durvalumab with R-CHOP or R, Grzegorz S Nowakowski, Wolfgang Willenbacher, Richard Greil, Thomas S Larsen, Krish Patel, Ulrich Jäger, Robert F Manges, Lorenz Trümper, Hele Everaus, Nagesh Kalakonda, Peter Brown, Judit Meszaros Jørgensen, David Cunningham, Justine Dell'Aringa, Brian Fox, Neus Domper Rubio, Nurgul Kilavuz, Marie-Laure Casadebaig, Oliver Manzke, and Javier Munoz

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Allogeneic Transplantation in Fit Older Adults Is Feasible and Encouragingly Efficacious. Post Remission Data from the Prospective ECOG-ACRIN (E2906) Clinical Study, Yishai Ofran, John E Godwin, and See full list of authors in comments

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PRoBE the cloud toolkit: finding the best biomarkers of drug response within a breast cancer clinical trial., Nicholas O'Grady, David L Gibbs, Kawther Abdilleh, Adam Asare, Smita Asare, Sara Venters, Lamorna Brown-Swigart, Gillian L Hirst, Denise Wolf, Christina Yau, Laura J van 't Veer, Laura Esserman, and Amrita Basu

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The TIME Trial® Network facilitates rapid clinical trial activation, patient screening, and enrollment in molecularly targeted trials, Stephanie O'Leary, Megan Shulman, Kevin Ritt, Meghan Degele, Ewelina Protomastro, Jennifer Clauson, Amy Franzen, Ian Churchill Anderson, Minal A. Barve, David N. Oubre, Victor Priego, Angela Saverimuthu, Francis Mark Senecal, Raju Kumar Vaddepally, Kimberly L. Blackwell, and Matthew M. Cooney

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RaPiDS (GOG-3028): randomized Phase II study of balstilimab alone or in combination with zalifrelimab in cervical cancer., David M O'Malley, Leslie M Randall, Camille Gunderson Jackson, Robert L Coleman, John L Hays, Kathleen N Moore, R Wendel Naumann, Rodney P Rocconi, Brian M Slomovitz, Krishnansu S Tewari, Marek Ancukiewicz, Waldo Ortuzar Feliu, and Bradley J Monk

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Breast MRI during Neoadjuvant Chemotherapy: Lack of Background Parenchymal Enhancement Suppression and Inferior Treatment Response., Natsuko Onishi, Wen Li, David C Newitt, Roy J Harnish, Fredrik Strand, Alex Anh-Tu Nguyen, Vignesh Amal Arasu, Jessica Gibbs, Ella F Jones, Lisa J Wilmes, John Kornak, Bonnie N Joe, Elissa R Price, Haydee Ojeda-Fournier, Mohammad Eghtedari, Kathryn W Zamora, Stefanie Woodard, Heidi R Umphrey, Michael T Nelson, An L Church, Patrick J Bolan, Theresa Kuritza, Kathleen Ward, Kevin Morley, Dulcy Wolverton, Kelly Fountain, Dan Lopez Paniagua, Lara Hardesty, Kathleen R Brandt, Elizabeth S McDonald, Mark Rosen, Despina Kontos, Hiroyuki Abe, Deepa Sheth, Erin Crane, Charlotte Dillis, Pulin Sheth, Linda Hovanessian-Larsen, Dae Hee Bang, Bruce Porter, Karen Y Oh, Neda Jafarian, Luminita A Tudorica, Bethany Niell, Jennifer Drukteinis, Mary S Newell, Marina E Giurescu, Elise Berman, Constance D Lehman, Savannah C Partridge, Kimberly A Fitzpatrick, Marisa H Borders, Wei Tse Yang, Basak Dogan, Sally Hayward Goudreau, Thomas Chenevert, Christina Yau, Angela DeMichele, Donald A Berry, Laura J Esserman, and Nola M Hylton

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Radiotherapy Versus Inguinofemoral Lymphadenectomy as Treatment for Vulvar Cancer Patients With Micrometastases in the Sentinel Node: Results of GROINSS-V II., Maaike H M Oonk, Brian Slomovitz, Peter J W Baldwin, Helena C van Doorn, Jacobus van der Velden, Joanne A de Hullu, Katja N Gaarenstroom, Brigitte F M Slangen, Ignace Vergote, Mats Brännström, Eleonora B L van Dorst, Willemien J van Driel, Ralph H Hermans, David Nunns, Martin Widschwendter, David Nugent, Cathrine M Holland, Aarti Sharma, Paul A DiSilvestro, Robert Mannel, Dorry Boll, David Cibula, Al Covens, Diane Provencher, Ingo B Runnebaum, David Luesley, Patricia Ellis, Timothy J Duncan, Ming Y Tjiong, Derek J Cruickshank, Preben Kjølhede, Charles F Levenback, Jiri Bouda, Katharina E Kieser, Connie Palle, Nicola M Spirtos, David M O'Malley, Mario M Leitao, Melissa A Geller, Kalyan Dhar, Viren Asher, Karl Tamussino, Daniel H Tobias, Christer Borgfeldt, Jayanthi S Lea, Jo Bailey, Margareta Lood, Brynhildur Eyjolfsdottir, Stephen Attard-Montalto, Krishnansu S Tewari, Ranjit Manchanda, Pernille T Jensen, Par Persson, Linda Van Le, Hein Putter, Geertruida H de Bock, Bradley J Monk, Carien L Creutzberg, and Ate G J van der Zee

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ASO Author Reflections: Molecular Testing in Breast Cancer: Is Core Biopsy Equivalent to Surgical Specimen?, Javier I Orozco and Janie Grumley

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Is the 21-Gene Recurrence Score on Core Needle Biopsy Equivalent to Surgical Specimen in Early-Stage Breast Cancer? A Comparison of Gene Expression Between Paired Core Needle Biopsy and Surgical Specimens., Javier I J Orozco, Shu-Ching Chang, Chikako Matsuba, Miquel Ensenyat-Mendez, Gary L Grunkemeier, Diego M Marzese, and Janie G Grumley

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ASO Visual Abstract: Is the 21-Gene Recurrence Score on Core Needle Biopsy Equivalent to Surgical Specimen in Early-Stage Breast Cancer? : A Comparison of Gene Expression Between Paired Core Needle Biopsy and Surgical Specimens., Javier I J Orozco, Shu-Ching Chang, Chikako Matsuba, Miquel Ensenyat-Mendez, Gary L Grunkemeier, Diego M Marzese, and Janie G Grumley

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Associations between complete remission and 2- to 3-year survival following 7 + 3 induction for acute myeloid leukemia., Megan Othus, Guillermo Garcia-Manero, John E Godwin, James Weick, Derek Stirewalt, Frederick Appelbaum, Harry Erba, and Elihu Estey

Advances in Immunotherapy, David B Page

Teaming up to Finish Triple-Negative Breast Cancer, David B Page

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399 A phase II study of nivolumab, ipilimumab, plus androgen receptor blockade with bicalutamide to enhance thymic T-cell production and immunotherapy response in metastatic breast cancer, David B Page, Krystle Collins, Brie Chun, Zhaoyu Sun, Yoshinobu Koguchi, William L. Redmond, Maritza Martel, Yaping Wu, Nikki Moxon, Staci Mellinger, Walter Urba, Ayca Gucalp, and Tiffany Traina

A phase II study of nivolumab, ipilimumab, plus androgen receptor blockade with bicalutamide to enhance thymic T-cell production and immunotherapy response in metastatic breast cancer, David B Page, Krystle Collins, Brie Chun, Zhaoyu Sun, Yoshinobu Koguchi, William D Ryan, Maritza Martel, Yaping Wu, Nikki Moxon, Staci Mellinger, Walter Urba, Ayca Gucalp, and Tiffany A. Traina

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OT1-18-04. A phase II study of dual immune checkpoint blockade (ICB) plus bicalutamide to enhance thymic T-cell production and immunotherapy response in metastatic breast cancer (MBC), David B Page, Krystle L. Collins, Brie Chun, Zhaoyu Sun, William L. Redmond, Maritza Martel, Yaping Wu, Nikki Moxon, Staci Mellinger, Walter Urba, Tiffany Traina, and Ayca Gucalp

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Molecular interaction study of novel indoline derivatives with EGFR-kinase domain using multiple computational analysis., Suresh Palanivel, Olli Yli-Harja, and Meenakshisundaram Kandhavelu

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A Randomized Phase II Study of Androgen Deprivation Therapy with or without Palbociclib in RB-positive Metastatic Hormone Sensitive Prostate Cancer (mHSPC)., Phillip L Palmbos, Stephanie Daignault-Newton, Scott A Tomlins, Neeraj Agarwal, Przemyslaw Twardowski, Alicia K Morgans, William K Kelly, Vivek K Arora, Emmanuel S Antonarakis, Javed Siddiqui, Jon Jacobson, Mathew S Davenport, Dan R Robinson, Arul M Chinnaiyan, Karen E Knudsen, and Maha Hussain

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Postinfusion monitoring costs by site of care for patients with relapsed/refractory large B-cell lymphoma receiving third- or later-line treatment with lisocabtagene maraleucel in the TRANSCEND NHL 001 and OUTREACH trials., M Lia Palomba, Monika Parisi Jun, James Lymp, Andy Nguyen, November McGarvey, Matthew Gitlin, Corey Pelletier, Scott J Keating, and John Godwin

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Discovery of Small Molecule Bak Activator for Lung Cancer Therapy., Dongkyoo Park, Abu Syed Md Anisuzzaman, Andrew T Magis, Guo Chen, Maohua Xie, Guojing Zhang, Madhusmita Behera, Gabriel L Sica, Suresh S Ramalingam, Taofeek K Owonikoko, and Xingming Deng

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Translating 2019 ACSM Cancer Exercise Recommendations for a Physiatric Practice - Derived recommendations from an international expert panel., Sara C Parke, Amy Ng, Patrick Martone, Lynn H Gerber, David S Zucker, Jessica Engle, Ekta Gupta, Katherine Power, Jonas Sokolof, Sam Shapar, Leslie Bagay, Bruce E Becker, and David Michael Langelier

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A Systems Approach to Brain Tumor Treatment., James H Park, Adrian Lopez Garcia de Lomana, Diego M Marzese, Tiffany Juarez, Abdullah Feroze, Parvinder Hothi, Charles Cobbs, Anoop P Patel, Santosh Kesari, Sui Huang, and Nitin S Baliga

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Amivantamab in EGFR Exon 20 Insertion-Mutated Non-Small-Cell Lung Cancer Progressing on Platinum Chemotherapy: Initial Results From the CHRYSALIS Phase I Study., Keunchil Park, Eric B Haura, Natasha B Leighl, Paul Mitchell, Catherine A Shu, Nicolas Girard, Santiago Viteri, Ji-Youn Han, Sang-We Kim, Chee Khoon Lee, Joshua K Sabari, Alexander I Spira, Tsung-Ying Yang, Dong-Wan Kim, Ki Hyeong Lee, Rachel E Sanborn, José Trigo, Koichi Goto, Jong-Seok Lee, James Chih-Hsin Yang, Ramaswamy Govindan, Joshua M Bauml, Pilar Garrido, Matthew G Krebs, Karen L Reckamp, John Xie, Joshua C Curtin, Nahor Haddish-Berhane, Amy Roshak, Dawn Millington, Patricia Lorenzini, Meena Thayu, Roland E Knoblauch, and Byoung Chul Cho

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1247P - Management of infusion-related reactions (IRRs) in patients receiving amivantamab, K Park, JK Sabari, EB Haura, CA Shu, A Spira, R Salgia, KL Reckamp, Rachel E Sanborn, R Govindan, JM Bauml, JC Curtin, J Xie, A Roshak, P Lorenzini, D Millington, M Thayu, RE Knoblauch, and BC Cho

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Immune checkpoint inhibitor therapy in HIV-associated Merkel cell carcinoma: A case series of 3 patients., Song Y Park, Candice Church, Nora A Alexander, Michi M Shinohara, Kelly G Paulson, Karl D Lewis, Nancy S Lee, and Paul Nghiem

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TBX2 Drives Neuroendocrine Prostate Cancer through Exosome-Mediated Repression of miR-200c-3p., Girijesh Kumar Patel, Sayanika Dutta, Mosharaf Mahmud Syed, Sabarish Ramachandran, Monica Sharma, Venkatesh Rajamanickam, Vadivel Ganapathy, David J DeGraff, Kevin Pruitt, Manisha Tripathi, and Srinivas Nandana

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Current and future treatment strategies in chronic lymphocytic leukemia., Krish Patel and John M Pagel

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A phase 1 study of SGN-B6A, an antibody-drug conjugate targeting integrin beta-6, in patients with advanced solid tumors (SGNB6A-001, Trial in Progress)., Amita Patnaik, Emiliano Calvo, Rachel E Sanborn, and See list of authors in comments

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miRNome and Functional Network Analysis of PGRMC1 Regulated miRNA Target Genes Identify Pathways and Biological Functions Associated With Triple Negative Breast Cancer., Diego A Pedroza, Matthew Ramirez, Venkatesh Rajamanickam, Ramadevi Subramani, Victoria Margolis, Tugba Gurbuz, Adriana Estrada, and Rajkumar Lakshmanaswamy

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Double the Battle: Two Cases of Irreversible Endocrinopathies in Patients Already Fighting Metastatic Cancer., Olesya Petrenko and Nicholas L Stucky

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Mobile Smartphone Thermal Imaging Characterization and Identification of Microvascular Flow Insufficiencies in Deep Inferior Epigastric Artery Perforator Free Flaps., Cody J Phillips, Morgan R Barron, John Kuckelman, Michael Derickson, Vance Y Sohn, Keith T Paige, and Kevin Beshlian

Integrated Personal Omics Profiling for Obesity, Brian D. Piening

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Palbociclib (P) in patients (pts) with head and neck cancer (HNC) with CDKN2A loss or mutation: Results from the Targeted Agent and Profiling Utilization Registry (TAPUR) study., Evan P. Pisick, Matthew Rothe, Rom Leidner, and See list of authors in comments

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961MO - Safety, efficacy, immunogenicity of arenavirus-based vectors HB-201 and HB-202 in patients with HPV16+ cancers, MR Posner, AL Ho, J Niu, L Nabell, Rom Leidner, J Nieva, DL Richardson, AT Pearson, D Wang, K Chung, DR Adkins, A Pimentel, S Wong, C Iacobucci, X Qing, K Katchar, K Schlienger, I Matushansky, S Fu, and DG Pfister

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Targeted genomic analysis of 364 adrenocortical carcinomas., Nikita Pozdeyev, Lauren Fishbein, Laurie M Gay, Ethan S Sokol, Ryan Hartmaier, Jeffrey S Ross, Sourat Darabi, Michael J Demeure, Adwitiya Kar, Lindsey J Foust, Katrina Koc, Daniel W Bowles, Stephen Leong, Margaret E Wierman, and Katja Kiseljak-Vassiliades

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Intralesional TTI-621, a novel biologic targeting the innate immune checkpoint CD47, in patients with relapsed or refractory mycosis fungoides or Sézary syndrome: a multicentre, phase 1 study., Christiane Querfeld, John A Thompson, Matthew H Taylor, Jennifer A DeSimone, Jasmine M Zain, Andrei R Shustov, Carolyn Johns, Sue McCann, Gloria H Y Lin, Penka S Petrova, Robert A Uger, Naomi Molloy, Yaping Shou, and Oleg E Akilov

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Phase II study of the histone deacetylase inhibitor vorinostat (Suberoylanilide Hydroxamic Acid; SAHA) in recurrent or metastatic transitional cell carcinoma of the urothelium - an NCI-CTEP sponsored: California Cancer Consortium trial, NCI 6879., David I Quinn, Denice D Tsao-Wei, Przemyslaw Twardowski, Ana M Aparicio, Paul Frankel, Gurkamal Chatta, John J Wright, Susan G Groshen, Stella Khoo, Heinz-Josef Lenz, Primo N Lara, David R Gandara, and Edward Newman

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Robust Antitumor Immunity in a Patient with Metastatic Colorectal Cancer Treated with Cytotoxic Regimens., Venkatesh Rajamanickam, Carmen Ballesteros-Merino, Kimberly Samson, David Ross, Brady Bernard, Bernard A Fox, Pippa Newell, Thomas Duhen, and Eric Tran

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1360TiP First-line (1L) maintenance therapy with niraparib (nira) + pembrolizumab (pembro) vs placebo + pembro in advanced/metastatic non-small cell lung cancer (NSCLC): Phase III ZEAL-1L study, SS Ramalingam, G de Castro Jr, MCC Garassino, J Mazieres, Rachel E Sanborn, EFF Smit, DR Spigel, M Thomas, V Velcheti, E Zhi, M Whipple Neibauer, A Stojadinovic, and S Peters

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Eosinophilic fasciitis as a paraneoplastic syndrome in melanoma., Andrea Rea, Alexis Anderson, Ata Moshiri, Kelly G Paulson, John A Thompson, and Andrea Kalus

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Progression to pseudomyxoma peritonei in patients with low grade appendiceal mucinous neoplasms discovered at time of appendectomy., Shelby Reiter, Colin J Rog, Mohamed Alassas, and Evan Ong

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Efficient antigen cross-presentation through coating conventional aluminum adjuvant particles with PEI., Hongyan Ren, Yongbin Mou, Lin Lin, Lixin Wang, and Hongming Hu

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558TiP - Phase I study of effector-function enhanced monoclonal antibody (mAb), SEA-TGT, in advanced malignancies, V Ribrag, D Davar, E Garralda, G Curigliano, J Zain, A Mehta, A Minchom, Rachel E Sanborn, F Foss, HK Oberoi, A Forero-Torres, and S Ansell

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Predictive biomarkers with isatuximab plus pomalidomide and dexamethasone in relapsed/refractory multiple myeloma., Paul G Richardson, Thierry Facon, William I Bensinger, Xavier Leleu, Frank Campana, Sandrine Macé, Marielle Chiron, Helgi van de Velde, and Joseph Mikhael

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Integrative modeling identifies genetic ancestry-associated molecular correlates in human cancer., A Gordon Robertson, Christina Yau, Jian Carrot-Zhang, Jeffrey S Damrauer, Theo A Knijnenburg, Nyasha Chambwe, Katherine A Hoadley, Anab Kemal, Jean C Zenklusen, Andrew D Cherniack, Rameen Beroukhim, and Wanding Zhou

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Evaluation of Indocyanine Green Fluorescence Imaging for Intraoperative Identification of Liver Malignancy., Jorge G Zarate Rodriguez, Jan Grendar, Zeljka Jutric, Maria A Cassera, Ronald F Wolf, Paul D Hansen, and Chet W Hammill

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COVID-19 in patients with CLL: improved survival outcomes and update on management strategies., Lindsey Elizabeth Roeker, Toby Andrew Eyre, Meghan C Thompson, Nicole Lamanna, Alexander Coltoff, Matthew S Davids, Peter Baker, Lori A Leslie, Kerry A Rogers, John N Allan, Raul Cordoba, Alberto Lopez-Garcia, Darko Antic, John M Pagel, Nicolás Martinez-Calle, Jose Antonio Garcia-Marco, José-Ángel Hernández-Rivas, Fatima Miras, Catherine C Coombs, Anders Österborg, Amanda N Seddon, Javier López-Jiménez, Matthew R Wilson, Dima El-Sharkawi, Daniel Wojenski, Shuo Ma, Talha Munir, Susana Valenciano, Erlene Seymour, Paul M Barr, Jeffrey J Pu, Piers Em Patten, Guilherme Fleury Perini, Scott F Huntington, Helen Parry, Suchitra Sundaram, Alan P Skarbnik, Manali Kamdar, Ryan W Jacobs, Harriet Sarah Walter, Renata Walewska, Angus Broom, Sonia Lebowitz, Krista Isaac, Craig A Portell, Inhye E Ahn, Chaitra Ujjani, Mazyar Shadman, Sigrid S Skånland, Elise A Chong, and Anthony R Mato

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Optimal oncologic and perioperative outcomes of cytoreductive surgery with hyperthermic intraperitoneal chemotherapy are attainable at a community center., Colin J Rog, Gary Lucas, Shelby Reiter, Susan Vetto, Mohamed Alassas, and Evan Ong

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596 Combining Bempegaldesleukin (CD122-preferential IL-2 pathway agonist) and NKTR-262 (TLR7/8 agonist) pairs local innate activation with systemic CD8+ T cell expansion to enhance anti-tumor immunity, Annah S Rolig, Daniel Rose, Grace Helen McGee, Saul Kivimae, Werner Rubas, and William L. Redmond

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GM-CSF drives myelopoiesis, recruitment and polarisation of tumour-associated macrophages in cholangiocarcinoma and systemic blockade facilitates antitumour immunity., Luis I Ruffolo, Katherine M Jackson, Peyton C Kuhlers, Benjamin S Dale, Nathania M Figueroa Guilliani, Nicholas A Ullman, Paul R Burchard, Shuyang S Qin, Peter G Juviler, Jessica Millian Keilson, Ashley B Morrison, Mary Georger, Rachel Jewell, Laura M Calvi, Timothy M Nywening, Michael R O'Dell, Aram F Hezel, Luis De Las Casas, Gregory B Lesinski, Jen Jen Yeh, Roberto Hernandez-Alejandro, Brian A Belt, and David C Linehan

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Amivantamab in Post-platinum EGFR Exon 20 Insertion Mutant Non-small Cell Lung Cancer, JK Sabari, CA Shu, K Park, N Leighl, P Mitchell, S Kim, J Lee, D Kim, S Viteri, A Spira, J Han, J Trigo, CK Lee, KH Lee, N Girard, T Yang, K Goto, Rachel E Sanborn, JC Yang, J Xie, A Roshak, M Thayu, RE Knoblauch, and BC Cho

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601 Sequencing immunotherapy before lymphatic ablation unleashes cDC1-dependent antitumor immunity in HNSCC, Robert Saddami-Konefka, Shawn M. Jensen, Bernard A Fox, and See all authors in comments

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Physical Activity Patterns and Relationships With Cognitive Function in Patients With Breast Cancer Before, During, and After Chemotherapy in a Prospective, Nationwide Study., Elizabeth A Salerno, Eva Culakova, Amber S Kleckner, Charles E Heckler, Po-Ju Lin, Charles E Matthews, Alison Conlin, Lora Weiselberg, Jerry Mitchell, Karen M Mustian, and Michelle C Janelsins

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RAMOSE: An Open-Label Randomized Phase II Study of Osimertinib with or without Ramucirumab in TKI-Naïve EGFR-Mutant Metastatic NSCLC, A Saltos, C Baik, Rachel E Sanborn, E Shum, C Kim, R Hall, MJ Fidler, CA Shu, G Otterson, J Patel, K Wong, N Hanna, J Gray, J Heymach, and X Le

Immunotherapy Combos: LAG-3, TIM-3, TIGIT, OX-40, Rachel E Sanborn

OncLive Data Review: ESMO Congress 2021, Rachel E Sanborn

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A phase 1 dose-escalation study of a PD-L1xCD27 bispecific antibody CDX-527 in patients with advanced malignancies., Rachel E Sanborn, Rodolfo E. Bordoni, and See author list in comments

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Sanborn and Gaffar Share Clinical and Economic Treatment Insights in NSCLC, Rachel E Sanborn and Yousuf A. Gaffar

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CX-072 (pacmilimab), a Probody PD-L1 inhibitor, in combination with ipilimumab in patients with advanced solid tumors (PROCLAIM-CX-072): a first-in-human, dose-finding study., Rachel E Sanborn, Omid Hamid, Elisabeth Ge de Vries, Patrick A Ott, Javier Garcia-Corbacho, Valentina Boni, Johanna Bendell, Karen A Autio, Daniel C Cho, Ruth Plummer, Mark Stroh, Lawrence Lu, and Fiona Thistlethwaite

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398 neoIRX: a phase II trial of locoregional cytokine therapy to promote immunologic priming and clinical response to neoadjuvant pembrolizumab plus chemotherapy in triple negative breast cancer (TNBC), Katherine Sanchez, Alison Conlin, Parvin Peddi, Sasha Stanton, Janet Ruzich, Kelly S Perlewitz, Yaping Wu, Nikki Moxon, Staci Mellinger, Zhaoyu Sun, William L. Redmond, and David B Page

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OT1-18-03. The neoIRX trial:locoregional cytokine therapy to promote immunologic priming and enhanced response to neoadjuvant pembrolizumab plus chemotherapy in triple negative breast cancer (TNBC), Katherine Sanchez, Alison Conlin, Parvin Peddi, Sasha Stanton, Janet Ruzich, Kelly S Perlewitz, Yaping Wu, Nikki Moxon, Staci Mellinger, Zhaoyu Sun, William L. Redmond, and David B Page

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Multiplex immunofluorescence to measure dynamic changes in tumor-infiltrating lymphocytes and PD-L1 in early-stage breast cancer., Katherine Sanchez, Isaac Kim, Brie Chun, Joanna Pucilowska, William L. Redmond, Walter Urba, Maritza Martel, Yaping Wu, Mary Campbell, Zhaoyu Sun, Gary Grunkemeier, Shu-Ching Chang, Brady Bernard, and David B Page

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Increased Intracranial Pressure: The Use of an Individualized Ladder Approach., Marlon G Saria and Santosh Kesari

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Lifileucel, a Tumor-Infiltrating Lymphocyte Therapy, in Metastatic Melanoma., Amod A Sarnaik, Omid Hamid, Nikhil I Khushalani, Karl D Lewis, Theresa Medina, Harriet M Kluger, Sajeve S Thomas, Evidio Domingo-Musibay, Anna C Pavlick, Eric D Whitman, Salvador Martin-Algarra, Pippa Corrie, Brendan D Curti, Judit Oláh, Jose Lutzky, Jeffrey S Weber, James M G Larkin, Wen Shi, Toshimi Takamura, Madan Jagasia, Harry Qin, Xiao Wu, Cecile Chartier, Friedrich Graf Finckenstein, Maria Fardis, John M Kirkwood, and Jason A Chesney

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SmartPhrase: Development of an Electronic Health Record System to Promote Chemotherapy and Immunotherapy Safety., Mary Jo Sarver, Monica McManus, Amy Allen, Bethany Johnson, and Dennielle Padgett

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Development of a SmartPhrase in the electronic health record to promote chemotherapy and immunotherapy safety, Mary Jo Sarver, Monica McManus, Amy Allen, Bethany Johnson, Dennielle Padgett, and Elizabeth Ser

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Germline genetic contribution to the immune landscape of cancer., Rosalyn W Sayaman, Mohamad Saad, Vésteinn Thorsson, Donglei Hu, Wouter Hendrickx, Jessica Roelands, Eduard Porta-Pardo, Younes Mokrab, Farshad Farshidfar, Tomas Kirchhoff, Randy F Sweis, Oliver F Bathe, Carolina Heimann, Michael J Campbell, Cynthia Stretch, Scott Huntsman, Rebecca E Graff, Najeeb Syed, Laszlo Radvanyi, Simon Shelley, Denise Wolf, Francesco M Marincola, Michele Ceccarelli, Jérôme Galon, Elad Ziv, and Davide Bedognetti

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Testing the acceptability and feasibility of a tablet-based supportive cancer platform for patients with metastatic breast cancer., Kathryn H Schmitz, Erica Schleicher, Shawna Doerksen, Christina Truica, Leah Cream, Rena Kass, Michelle Farnan, Robin Suess, Brett Gordon, David S Zucker, and Michael Hayes

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Phase I trial of intranasal NEO100, highly purified perillyl alcohol, in adult patients with recurrent glioblastoma., Axel H Schönthal, David M Peereboom, Naveed Wagle, Rose Lai, Anna J Mathew, Kyle M Hurth, Vincent F Simmon, Steven P Howard, Lynne P Taylor, Frances Chow, Clovis O da Fonseca, and Thomas C Chen

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Pegfilgrastim Biosimilars: Where Are We Now?, Christopher Selby, Breanne Peyton-Thomas, and Parnian Eslami

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Influence of Socioeconomic Status on Incident Medical Conditions in Two-Year Survivors of Adolescent or Young Adult Differentiated Thyroid Cancer., Thomas J Semrad, Qian Li, Melanie Goldfarb, Alison Semrad, Michael Campbell, D Gregory Farwell, and Theresa H M Keegan

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A Phase Ib/II Study of Pepinemab in Combination with Avelumab in Advanced Non-Small Cell Lung Cancer., Michael R Shafique, Terrence L Fisher, Elizabeth E Evans, John E Leonard, Desa Rae E Pastore, Crystal L Mallow, Ernest Smith, Vikas Mishra, Andreas Schröder, Kevin M Chin, Joseph T Beck, Megan A Baumgart, Ramaswamy Govindan, Nashat Y Gabrail, Alexander I Spira, Nagashree Seetharamu, Yanyan Lou, Aaron S Mansfield, Rachel E Sanborn, Jonathan W Goldman, and Maurice Zauderer

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KTE-X19 anti-CD19 CAR T-cell therapy in adult relapsed/refractory acute lymphoblastic leukemia: ZUMA-3 phase 1 results., Bijal D Shah, Michael R Bishop, Olalekan O Oluwole, Aaron C Logan, Maria R Baer, William B Donnellan, Kristen M O'Dwyer, Houston Holmes, Martha L Arellano, Armin Ghobadi, John M Pagel, Yi Lin, Ryan D Cassaday, Jae Park, Mehrdad Abedi, Januario Castro, Daniel J DeAngelo, Adriana K Malone, Raya Mawad, Gary Schiller, John Michael Rossi, Adrian Bot, Tong Shen, Lovely Goyal, Rajul K Jain, Remus Vezan, and William George Wierda

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Correction to: The Clinical Utility of DCISionRT, Chirag Shah, Troy Bremer, Charles Cox, Pat Whitworth, Rakesh Patel, Anushka Patel, Eric Brown, Linsey Gold, David Rock, Lee Riley, Christy Kesslering, Sheree Brown, Robert Gabordi, James Pellicane, Rachel Rabinovich, Sadia Khan, Sandra Templeton, Lonika Majithia, Shawna C Willey, Fredrik Wärnberg, Naamit K Gerber, Steve Shivers, and Frank A Vicini

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The Clinical Utility of DCISionRT, Chirag Shah, Troy Bremer, Charles Cox, Pat Whitworth, Rakesh Patel, Anushka Patel, Eric Brown, Linsey Gold, David Rock, Lee Riley, Christy Kesslering, Sheree Brown, Robert Gabordi, James Pellicane, Rachel Rabinovich, Sadia Khan, Sandra Templeton, Lonika Majithia, Shawna C Willey, Fredrik Wärnberg, Naamit K Gerber, Steve Shivers, and Frank A Vicini

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Perspectives and Impacts of the Pending US Radiation Oncology Alternative Payment Model., Chirag Shah and Jeffery C Ward

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Gelatin methacrylate hydrogels culture model for glioblastoma cells enriches for mesenchymal-like state and models interactions with immune cells., Nameeta Shah, Pavan M Hallur, Raksha A Ganesh, Pranali Sonpatki, Divya Naik, Komal Prasad Chandrachari, Ralph B Puchalski, and Aditya Chaubey

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Genomic and Molecular Profiling of Human Papillomavirus Associated Head and Neck Squamous Cell Carcinoma Treated with Immune Checkpoint Blockade Compared to Survival Outcomes., Hira Shaikh, Julie E McGrath, Brittany Hughes, Joanne Xiu, Pavel Brodskiy, Ammar Sukari, Sourat Darabi, Chukwuemeka Ikpeazu, Chadi Nabhan, Wolfgang Michael Korn, and Trisha M Wise-Draper

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Plasma MMP-2 and MMP-7 levels are elevated first month after surgery and may promote growth of residual metastases., Hmc Shantha Kumara, Hiromichi Miyagaki, Sajith A Herath, Erica Pettke, Xiaohong Yan, Vesna Cekic, and Richard L Whelan

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Supportive care for patients with brain metastases from lung cancer., Akanksha Sharma and Maciej M Mrugala

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Updates on Molecular Targeted Therapies for Intraparenchymal CNS Metastases., Akanksha Sharma, Lauren Singer, and Priya Kumthekar

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A platform for locoregional T-cell immunotherapy to control HNSCC recurrence following tumor resection., Shay Sharon, Jason R Baird, Shelly Bambina, Gwen Kramer, Tiffany C Blair, Shawn M Jensen, Rom S Leidner, R Bryan Bell, Nardy Casap, Marka R Crittenden, and Michael J Gough

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Explant Modeling of the Immune Environment of Head and Neck Cancer., Shay Sharon, Thomas Duhen, Shelly Bambina, Jason Baird, Rom Leidner, Bryan Bell, Nardy Casap, Marka Crittenden, Swetha Vasudevan, Maria Jubran, Nataly Kravchenko-Balasha, and Michael Gough

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Open-label, phase II study of ladiratuzumab vedotin (LV) for castration-resistant prostate cancer (SGNLVA-005, trial-in-progress)., Amna Falak Sher, Justine Yang Bruce, Nashat Y. Gabrail, Ian Churchill Anderson, Anna Patrikidou, Rachel E Sanborn, Jae Yong Cho, Arielle Shebay Lee, Jong-Seok Lee, Louise M. Nott, Do-Youn Oh, Sang Cheul Oh, Sung Yong Oh, Yinghui Wang, Zejing Wang, and Troy H. Guthrie

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Current status of gastrointestinal tract cancer brain metastasis and the use of blood-based cancer biomarker biopsy., Yoshiaki Shoji, Satoru Furuhashi, Daniel F Kelly, Anton J Bilchik, Dave S B Hoon, and Matias A Bustos

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Impact of Comorbidities on Outcomes and Toxicity in Patients Treated with CAR T-Cell Therapy for Diffuse Large B Cell Lymphoma (DLBCL): A Multicenter Rwe Study, Geoffrey Shouse, Neil Bailey, Krish Patel, and See all authors in comments

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1193MO - Amivantamab plus lazertinib in post-osimertinib, post-platinum chemotherapy EGFR-mutant non-small cell lung cancer (NSCLC): Preliminary results from CHRYSALIS-2, CA Shu, K Goto, Y Ohe, B Besse, K Park, Y Wang, F Griesinger, JC Yang, E Felip, Rachel E Sanborn, R Bernabe Caro, JM Bauml, J Chen, E Fennema, J Mahoney, L Trani, RE Knoblauch, M Thayu, and BC Chou

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523 Preliminary clinical experience with XmAb20717, a PD-1 x CTLA-4 bispecific antibody, in patients with advanced solid tumors, Elaine Shum, Rom Leidner, and See full list of authors in comments

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Multicenter, double-blind, placebo-controlled trial of seviprotimut-L polyvalent melanoma vaccine in patients with post-resection melanoma at high risk of recurrence., Craig L Slingluff, Karl D Lewis, Robert Andtbacka, John Hyngstrom, Mohammed Milhem, Svetomir N Markovic, Tawnya Bowles, Omid Hamid, Leonel Hernandez-Aya, Joel Claveau, Sekwon Jang, Prejesh Philips, Shernan G Holtan, Montaser F Shaheen, Brendan Curti, William Schmidt, Marcus O Butler, Juan Paramo, Jose Lutzky, Arvinda Padmanabhan, Sajeve Thomas, Daniel Milton, Andrew Pecora, Takami Sato, Eddy Hsueh, Suprith Badarinath, John Keech, Sujith Kalmadi, Pallavi Kumar, Robert Weber, Edward Levine, Adam Berger, Anna Bar, J Thaddeus Beck, Jeffrey B Travers, Catalin Mihalcioiu, Brian Gastman, Peter Beitsch, Suthee Rapisuwon, John Glaspy, Edward C McCarron, Vinay Gupta, Deepti Behl, Brent Blumenstein, and Joanna J Peterkin

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Psychometric Characteristics and Validity of the PROMIS Cancer Function Brief 3D Profile., Sean R Smith, Mary Vargo, David Zucker, Samman Shahpar, Lynn Gerber, Maryanne Henderson, Gina Jay, Minji Lee, and Andrea Cheville

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Small molecules inhibitors of the heterogeneous ribonuclear protein A18 (hnRNP A18): a regulator of protein translation and an immune checkpoint., Eduardo Solano-Gonzalez, Katherine M Coburn, Wenbo Yu, Gerald M Wilson, Elmar Nurmemmedov, Santosh Kesari, Elizabeth T Chang, Alexander D MacKerell, David J Weber, and France Carrier