Providence’s research in kidney health and diseases is on the cutting edge of identifying molecular signatures of diabetic kidney disease and development of new biomarkers and treatment targets. Our work is broadly translational from cellular and molecular biology to studies in mouse models to translational studies in humans and clinical trials of novel therapies. We also conduct research in a broad spectrum of other types of kidney diseases and treatments: glomerular diseases, hypertension and kidney vascular disease, nutritional approaches, patient-centered outcomes, and health services research. Importantly, Providence has funded a major initiative to establish a system-wide Chronic Kidney Disease registry that will greatly amplify both the quality-of-care we deliver and the research we conduct in our communities. We truly are at a tipping point. Astounding scientific breakthroughs will change the landscape toward kidney health and better life for people with kidney diseases.

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Submissions from 2022

The Risks & Benefits of Finerenone, Katherine Tuttle

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Molecular mechanisms and therapeutic targets for diabetic kidney disease., Katherine Tuttle, Rajiv Agarwal, Charles E Alpers, George L Bakris, Frank C Brosius, Peter Kolkhof, and Jaime Uribarri

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Safety of Empagliflozin in Patients With Type 2 Diabetes and Chronic Kidney Disease: Pooled Analysis of Placebo-Controlled Clinical Trials., Katherine Tuttle, Adeera Levin, Masaomi Nangaku, Takashi Kadowaki, Rajiv Agarwal, Sibylle J Hauske, Amelie Elsäßer, Ivana Ritter, Dominik Steubl, Christoph Wanner, and David C Wheeler

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SGLT2 inhibitors as the bedrock of therapy for heart failure., Katherine Tuttle and Janani Rangaswami

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Incidence of Chronic Kidney Disease among Adults with Diabetes, 2015-2020., Katherine R Tuttle, Cami R Jones, Kenn B Daratha, Alain K Koyama, Susanne B Nicholas, Radica Z Alicic, O Kenrik Duru, Joshua J Neumiller, Keith C Norris, Nilka Ríos Burrows, and Meda E Pavkov

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Study Design of a Phase 2 Trial of the Aldosterone Synthase Inhibitor BI 690517 Alone and in Combination With Empagliflozin in Patients With Diabetic and Non-Diabetic CKD, Katherine Tuttle and See full list of authors in comments

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Are nephrometry scores accurate for the prediction of outcomes in patients with renal angiomyolipoma treated with robot-assisted partial nephrectomy? A multi-institutional analysis., Alessandro Uleri, Pietro Diana, Giovanni Lughezzani, Paolo Casale, Alberto Saita, Rodolfo Hurle, Massimo Lazzeri, Francesco Porpiglia, Cristian Fiori, Daniele Amparore, Paolo Verri, Giuseppe Rosiello, Alex Mottrie, Geert DE Naeyer, Ruben DE Groote, James R Porter, and Nicolomaria Buffi

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Robotic vs laparoscopic nephroureterectomy for upper tract urothelial carcinoma: a multicenter propensity-score matched pair "tetrafecta" analysis (ROBUUST collaborative group)., Alessandro Veccia, Umberto Carbonara, Hooman Djaladat, Reza Mehrazin, Daniel Eun, Adam C Reese, Xiaosong Meng, Robert Uzzo, Abhishek Srivastava, James R Porter, Jason Farrow, Marcus Jamil, Giuseppe Rosiello, Riccardo Tellini, Andrea Mari, Ali Al-Qathani, Koon Ho Rha, Linhui Wang, Riccardo Mastroianni, Matteo Ferro, Ottavio De Cobelli, Kevin Hakimi, Fabio Crocerossa, Alireza Ghoreifi, Giovanni Cacciamani, Amit Amit S Bhattu, Alexandre Mottrie, Firas Abdollah, Andrea Minervini, Zhenjie Wu, Giuseppe Simone, Ithaar H Derweesh, Mark L Gonzalgo, Vitaly Margulis, Chandru P Sundaram, and Riccardo Autorino

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Premature Death in Kidney Transplant Recipients: The Time for Trials is Now., Amanda J Vinson, Sunita Singh, Steven Chadban, David Cherney, Osama Gaber, John S Gill, Erika Helgeson, Charles A Herzog, Meg Jardine, Vivekanand Jha, Bertram L Kasiske, Roslyn B Mannon, Erin D Michos, Amy K Mottl, Kristin Newby, Prabir Roy-Chaudhury, Deirdre Sawinski, Adnan Sharif, Vikas S Sridhar, Katherine Tuttle, David M Vock, and Arthur Matas

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Novel Therapeutics and Treatment Strategies for Medullary Thyroid Cancer., Evan Walgama, Naifa Busaidy, and Mark Zafereo

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Heterogeneity in statin responses explained by variation in the human gut microbiome., Tomasz Wilmanski, Sergey A Kornilov, Christian Diener, Matthew P Conomos, Jennifer C Lovejoy, Paola Sebastiani, Eric S Orwoll, Leroy Hood, Nathan D Price, Noa Rappaport, Andrew T Magis, and Sean M Gibbons

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Corrigendum re "A Preoperative Nomogram to Predict Renal Function Insufficiency for Cisplatin-based Adjuvant Chemotherapy Following Minimally Invasive Radical Nephroureterectomy (ROBUUST Collaborative Group)" [Eur Urol Focus 2022;8:173-81]., Zhenjie Wu, Qi Chen, Hooman Djaladat, Andrea Minervini, Robert G Uzzo, Chandru Sundaram, Koon H Rha, Mark L Gonzalgo, Reza Mehrazin, Elio Mazzone, Jamil Marcus, Alyssa Danno, James R Porter, Aeen Asghar, Fady Ghali, Georgi Guruli, Antoin Douglawi, Giovanni Cacciamani, Alireza Ghoreifi, Giuseppe Simone, Vitaly Margulis, Matteo Ferro, Riccardo Tellini, Andrea Mari, Abhishek Srivastava, James Steward, Ali Al-Qathani, Ahmad Al-Mujalhem, Amit Satish Bhattu, Alexander Mottrie, Firas Abdollah, Daniel D Eun, Ithaar Derweesh, Alessandro Veccia, Riccardo Autorino, and Linhui Wang

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Kidney Biopsy Features Most Predictive of Clinical Outcomes in the Spectrum of Minimal Change Disease and Focal Segmental Glomerulosclerosis., Jarcy Zee, Qian Liu, Abigail R Smith, Jeffrey B Hodgin, Avi Rosenberg, Brenda W Gillespie, Lawrence B Holzman, Laura Barisoni, Laura H Mariani, Nephrotic Syndrome Study Network (NEPTUNE); NEPTUNE Members, and Katherine Tuttle

Submissions from 2021

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Automated Bolus Calculators and Connected Insulin Pens: A Smart Combination for Multiple Daily Injection Insulin Therapy., David T Ahn

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Transradial Access for High-Risk Percutaneous Coronary Intervention: Implications of the Risk-Treatment Paradox., Amit P Amin, Sunil V Rao, Arnold H Seto, Manoj Thangam, Richard G Bach, Samir Pancholy, Ian C Gilchrist, Prashant Kaul, Binita Shah, Mauricio G Cohen, Ty J Gluckman, Anna Bortnick, James T DeVries, Hemant Kulkarni, and Frederick A Masoudi

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Evaluation of FKBP5 as a cortisol activity biomarker in patients with ACTH-dependent Cushing syndrome., Irina Bancos, Betul Ayse Hatipoglu, Kevin C J Yuen, Lakshmi Chandramohan, Sandeep Chaudhari, and Andreas G Moraitis

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Fifteen-minute Frequency of Glucose Measurements and the Use of Threshold Alarms: Impact on Mitigating Dysglycemia in Critically Ill Patients., Grant V Bochicchio, Stanley A Nasraway, Laura J Moore, Anthony P Furnary, Eden A Nohra, Kelly M Bochicchio, James C Boyd, David I Bruns, Irl B Hirsch, Jean-Charles Preiser, and James S Krinsley

Phase Ic study of the aldosterone synthase inhibitor BI 690517 in patients with diabetic kidney disease, S Bornstein, Katherine Tuttle, and See full list of authors in comments

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Transforming the Care of Patients with Diabetic Kidney Disease., Frank Brosius Iii, David Cherney, Patrick Gee, Raymond Harris, Alan Kliger, Katherine Tuttle, and Susan Quaggin

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A Participant-Centered Approach to Understanding Risks and Benefits of Participation in Research Informed by the Kidney Precision Medicine Project., Catherine R Butler, Paul S Appelbaum, Heather Ascani, Mark Aulisio, Catherine E Campbell, Ian H de Boer, Ashveena L Dighe, Daniel E Hall, Jonathan Himmelfarb, Richard Knight, Karla Mehl, Raghavan Murugan, Sylvia E Rosas, John R Sedor, John F O'Toole, Katherine Tuttle, Sushrut S Waikar, Michael Freeman, and Kidney Precision Medicine Project

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Annals On Call - SGLT-2 Revisited: Diabetes Management in Chronic Kidney Disease, Robert M. Centor, Katherine Tuttle, and Jonathan Himmelfarb

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Mifepristone as Bridge or Adjunct Therapy in the Management of Challenging Cushing Disease Cases., Alice Y Chang, Sasan Mirfakhraee, Elizabeth E King, Kelley J Moloney, Diane M Donegan, and Kevin Cj Yuen

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Construct validity, ecological validity and acceptance of self-administered online neuropsychological assessment in adults., Naomi S Chaytor, Celestina Barbosa-Leiker, Laura T Germine, Luciana Mascarenhas Fonseca, Sterling M McPherson, and Katherine Tuttle

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The role of RENAL score in predicting complications after robotic partial nephrectomy., Jorge Daza, Kennedy E Okhawere, Olajumoke Ige, Amr Elbakry, John P Sfakianos, Ronney Abaza, Akshay Bhandari, Daniel D Eun, Ashok K Hemal, James R Porter, and Ketan K Badani

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Rationale and design of the Kidney Precision Medicine Project., Ian H de Boer, Charles E Alpers, Evren U Azeloglu, Ulysses G J Balis, Jonathan M Barasch, Laura Barisoni, Kristina N Blank, Andrew S Bomback, Keith Brown, Pierre C Dagher, Ashveena L Dighe, Michael T Eadon, Tarek M El-Achkar, Joseph P Gaut, Nir Hacohen, Yongqun He, Jeffrey B Hodgin, Sanjay Jain, John A Kellum, Krzysztof Kiryluk, Richard Knight, Zoltan G Laszik, Chrysta Lienczewski, Laura H Mariani, Robyn L McClelland, Steven Menez, Dennis G Moledina, Sean D Mooney, John F O'Toole, Paul M Palevsky, Chirag R Parikh, Emilio D Poggio, Sylvia E Rosas, Matthew R Rosengart, Minnie M Sarwal, Jennifer A Schaub, John R Sedor, Kumar Sharma, Becky Steck, Robert D Toto, Olga G Troyanskaya, Katherine Tuttle, Miguel A Vazquez, Sushrut S Waikar, Kayleen Williams, Francis Perry Wilson, Kun Zhang, Ravi Iyengar, Matthias Kretzler, Jonathan Himmelfarb, and Kidney Precision Medicine Project

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New pharmacological therapies to slow the progression of diabetic kidney disease: e-seminar #2 New guidelines to optimize the clinical care of people with diabetes and CKD, Ian De Boer, Katherine Tuttle, and Christoph Wanner

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Comparison of the Safety and Efficacy of Valveless and Standard Insufflation During Robotic Partial Nephrectomy: A Prospective, Randomized, Multi-institutional Trial., Bethany Desroches, James Porter, Sam Bhayani, Robert Figenshau, Ping-Yu Liu, and Michael Stifelman

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The Impact of Chronic Kidney Disease in Patients With Locally Advanced Rectal Cancer Treated With Neoadjuvant Chemoradiation., Shaan Dudani, Horia Marginean, Joanna Gotfrit, Patricia A Tang, Jose Gerard Monzon, Kristopher Dennis, Hagen F Kennecke, Erin D Powell, Sam Babak, Winson Y Cheung, and Michael M Vickers

Identification of kidney disease diagnosis in patients with diabetes by biopsies and electronic health records, E Fast, CR Jones, Kenn Daratha, Radica Alicic, Katherine Tuttle, and See all authors in comments

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Identification of kidney disease diagnoses in patients with diabetes by biopsies and electronic health records, Eva Fast, Cami R Jones, Kenn Daratha, Susanne B. Nicholas, Radica Alicic, Cynthia C. Nast, Jonathan E. Zuckerman, Sarthak Patel, Ken Allison, Adam Tebbe, Michelle Penny, Keith C. Norris, and Katherine Tuttle

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Identification of Kidney Disease Diagnoses in Patients with Diabetes by Biopsies and Electronic Health Records, Eva Fast, Cami R. Jones, Kenn Daratha, Susanne B. Nicholas, Radica Alicic, Cynthia C. Nast, Jonathan E. Zuckerman, Sarthak Patel, Adam Tebbe, Michelle Penny, Keith C. Norris, and Katherine Tuttle

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Large-scale, three-dimensional tissue cytometry of the human kidney: a complete and accessible pipeline., Michael J Ferkowicz, Seth Winfree, Angela R Sabo, Malgorzata M Kamocka, Suraj Khochare, Daria Barwinska, Michael T Eadon, Ying-Hua Cheng, Carrie L Phillips, Timothy A Sutton, Katherine J Kelly, Pierre C Dagher, Tarek M El-Achkar, Kenneth W Dunn, Kidney Precision Medicine Project, and Katherine Tuttle

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MRA’s in the future of DKD Management, Roberto Pecoits Filho, Katherine Tuttle, and See full list of authors in comments

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Consensus on diagnosis and management of Cushing's disease: a guideline update., Maria Fleseriu, Richard Auchus, Irina Bancos, Anat Ben-Shlomo, Jerome Bertherat, Nienke R Biermasz, Cesar L Boguszewski, Marcello D Bronstein, Michael Buchfelder, John D Carmichael, Felipe F Casanueva, Frederic Castinetti, Philippe Chanson, James Findling, Mônica Gadelha, Eliza B Geer, Andrea Giustina, Ashley Grossman, Mark Gurnell, Ken Ho, Adriana G Ioachimescu, Ursula B Kaiser, Niki Karavitaki, Laurence Katznelson, Daniel F Kelly, André Lacroix, Ann McCormack, Shlomo Melmed, Mark Molitch, Pietro Mortini, John Newell-Price, Lynnette Nieman, Alberto M Pereira, Stephan Petersenn, Rosario Pivonello, Hershel Raff, Martin Reincke, Roberto Salvatori, Carla Scaroni, Ilan Shimon, Constantine A Stratakis, Brooke Swearingen, Antoine Tabarin, Yutaka Takahashi, Marily Theodoropoulou, Stylianos Tsagarakis, Elena Valassi, Elena V Varlamov, Greisa Vila, John Wass, Susan M Webb, Maria C Zatelli, and Beverly M K Biller

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Degludec hospital trial: A randomized controlled trial comparing insulin degludec U100 and glargine U100 for the inpatient management of patients with type 2 diabetes., Rodolfo J Galindo, Francisco J Pasquel, Priyathama Vellanki, Radica Alicic, David W Lam, Maya Fayfman, Alexandra L Migdal, Georgia M Davis, Saumeth Cardona, Maria A Urrutia, Citlalli Perez-Guzman, Karla Walkiria Zamudio-Coronado, Limin Peng, Katherine Tuttle, and Guillermo E Umpierrez

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The microcirculatory response to endotoxemia and resuscitation is a marker of regional renal perfusion, renal metabolic stress and tubular injury., Hernando Gomez, Hakon Haugaa, Daniel Escobar, Ana M Botero, Rachel Pool, Gaspar Del Rio-Pertuz, Carlos L Manrique-Caballero, Lisa Gordon, Alicia Frank, Jean-Louis Teboul, Brian Zuckerbraun, and Michael R Pinsky

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Population Health Innovations and Payment to Address Social Needs Among Patients and Communities With Diabetes., Kathryn E Gunter, Monica E Peek, Jacob P Tanumihardjo, Evalyn Carbrey, Richard D Crespo, Trista W Johnson, Brenda Rueda-Yamashita, Eric I Schwartz, Catalina Sol, Cody M Wilkinson, J O Wilson, Emily Loehmer, and Marshall H Chin

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Dabigatran etexilate for the treatment of acute venous thromboembolism in children (DIVERSITY): a randomised, controlled, open-label, phase 2b/3, non-inferiority trial., Jacqueline Halton, Leonardo R Brandão, Matteo Luciani, Lisa Bomgaars, Elizabeth Chalmers, Lesley G Mitchell, Ildar Nurmeev, Anjali Sharathkumar, Pavel Svirin, Kirill Gorbatikov, Igor Tartakovsky, Monika Simetzberger, Fenglei Huang, Zhichao Sun, Jörg Kreuzer, Savion Gropper, Paul Reilly, Martina Brueckmann, Manuela Albisetti, DIVERSITY Trial Investigators, and Judy Felgenhauer (DIVERSITY Trial Investigator)

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Development and Validation of an Objective Scoring Tool for Robot-Assisted Partial Nephrectomy: Scoring for Partial Nephrectomy., Umar Iqbal, Zhe Jing, Youssef Ahmed, Ahmed S Elsayed, Craig Rogers, Ronald Boris, James R Porter, Mohammad Allaf, Ketan Badani, Michael Stifelman, Jihad Kaouk, Tomoaki Terakawa, Nobuyuki Hinata, Ahmed A Aboumohamed, Eric Kauffman, Qiang Li, Ronney Abaza, Khurshid A Guru, Ahmed A Hussein, and Daniel Eun

Characteristics of patients with chronic kidney disease and diabetes by use of ACE inhibitors of ARBs, CR Jones, Kenn Daratha, Radica Alicic, Katherine Tuttle, and See full list of authors in comments

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Risk Factors for Intravesical Recurrence after Minimally Invasive Nephroureterectomy for Upper Tract Urothelial Cancer (ROBUUST Collaboration)., Andrew B Katims, Rollin Say, Ithaar Derweesh, Robert Uzzo, Andrea Minervini, Zhenjie Wu, Firas Abdollah, Chandru Sundaram, Matteo Ferro, Koon Rha, Alex Mottrie, Giuseppe Rosiello, Giuseppe Simone, Daniel D Eun, Adam Reese, Laura C Kidd, James R Porter, Amit Satish Bhattu, Mark L Gonzalgo, Vitaly Margulis, Jamil Marcus, Alyssa Danno, Margaret Meagher, Riccardo Tellini, Andrea Mari, Alessandro Veccia, Alireza Ghoreifi, Riccardo Autorino, Hooman Djaladat, and Reza Mehrazin

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Ethical issues and obligations with undocumented immigrants relying on emergency departments for dialysis., Nicholas H Kluesner, Norine McGrath, Nathan G Allen, Monisha Dilip, and Jay Brenner

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Artificial Intelligence-Assisted Electrocardiography for Early Diagnosis of Thyrotoxic Periodic Paralysis., Chin Lin, Chin-Sheng Lin, Ding-Jie Lee, Chia-Cheng Lee, Sy-Jou Chen, Shi-Hung Tsai, Feng-Chih Kuo, Tom Chau, and Shih-Hua Lin

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Prostatic urethral lift for the treatment of lower urinary tract symptoms in men with benign prostatic hyperplasia: A Cochrane review summary., JoAnn D Long, Stephan R Smith, and Members of the Cochrane Nursing Care (CN)

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Nephron overload as a therapeutic target to maximize kidney lifespan., Valerie A Luyckx, Andrew D Rule, Katherine Tuttle, Pierre Delanaye, Helen Liapis, Afschin Gandjour, Paola Romagnani, and Hans-Joachim Anders

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Nephron overload as a therapeutic target to maximize kidney lifespan, Valerie A. Luyckx, Andrew D. Rule, Katherine Tuttle, Pierre Delanaye, Helen Liapis, Afschin Gandjour, Paola Romagnani, and Hans-Joachim Anders

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Defining Risk Categories for a Significant Decline in Estimated Glomerular Filtration Rate After Robotic Partial Nephrectomy: Implications for Patient Follow-up., Alberto Martini, Ugo Giovanni Falagario, Shivaram Cumarasamy, Ronney Abaza, Daniel D Eun, Akshay Bhandari, James R Porter, Ashok K Hemal, and Ketan K Badani

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In Reply - Neutralization of Fecal Aerosol-Laden SARS CoV-2: Public Health Implications., Carmen V McDermott, Emily J Cox, James M Scanlan, and Radica Alicic

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GLP-1 Receptor Agonists in Diabetic Kidney Disease., Erin D Michos and Katherine R Tuttle

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The Clinical Application of Urine Soluble CD163 in ANCA-Associated Vasculitis., Sarah M Moran, Jennifer Scott, Michael R Clarkson, Niall Conlon, Jean Dunne, Matthew D Griffin, Tomas P Griffin, Elizabeth Groarke, John Holian, Conor Judge, Jason Wyse, Kirsty McLoughlin, Paul V O'Hara, Mark A Little, Matthias Kretzler, Nephrotic Syndrome Study Network (NEPTUNE), and Katherine Tuttle

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Diabetes Management in Chronic Kidney Disease: Synopsis of the 2020 KDIGO Clinical Practice Guideline., Sankar D Navaneethan, Sophia Zoungas, M Luiza Caramori, Juliana C N Chan, Hiddo J L Heerspink, Clint Hurst, Adrian Liew, Erin D Michos, Wasiu A Olowu, Tami Sadusky, Nikhil Tandon, Katherine Tuttle, Christoph Wanner, Katy G Wilkens, Lyubov Lytvyn, Jonathan C Craig, David J Tunnicliffe, Martin Howell, Marcello Tonelli, Michael Cheung, Amy Earley, Peter Rossing, Ian H de Boer, and Kamlesh Khunti

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Overcoming Barriers to Implementing New Therapies for Diabetic Kidney Disease: Lessons Learned., Joshua J Neumiller, Radica Alicic, and Katherine Tuttle

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Overcoming Barriers to Implementing New Therapies for Diabetic Kidney Disease: Lessons Learned., Joshua J Neumiller, Radica Alicic, and Katherine Tuttle

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Optimizing use of SGLT2 inhibitors and other evidence-based therapies to improve outcomes in patients with type 2 diabetes and chronic kidney disease: An opportunity for pharmacists., Joshua J Neumiller, Jay H Shubrook, Tom Manley, Radica Z Alicic, and Katherine R Tuttle

Disparities in CKD risks: data from the CURE-CKD COVID-19 sub-registry, SB Nicholas, Kenn Daratha, CR Jones, Katherine Tuttle, and See full list of authors in comments

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Does glucose influence multidien cycles of interictal and/or ictal activities?, Alexa Pappas, Sanjay Kubsad, Maxime O Baud, Kyla E Wright, Devon M Kollmyer, Nicole M Warner, Alan M Haltiner, Ryder P Gwinn, and Michael J Doherty

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TBX2 Drives Neuroendocrine Prostate Cancer through Exosome-Mediated Repression of miR-200c-3p., Girijesh Kumar Patel, Sayanika Dutta, Mosharaf Mahmud Syed, Sabarish Ramachandran, Monica Sharma, Venkatesh Rajamanickam, Vadivel Ganapathy, David J DeGraff, Kevin Pruitt, Manisha Tripathi, and Srinivas Nandana

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Effect of High-frequency (10-kHz) Spinal Cord Stimulation in Patients With Painful Diabetic Neuropathy: A Randomized Clinical Trial., Erika A Petersen, Thomas G Stauss, James A Scowcroft, Elizabeth S Brooks, Judith L White, Shawn M Sills, Kasra Amirdelfan, Maged N Guirguis, Jijun Xu, Cong Yu, Ali Nairizi, Denis G Patterson, Kostandinos C Tsoulfas, Michael J Creamer, Vincent Galan, Richard H Bundschu, Christopher A Paul, Neel D Mehta, Heejung Choi, Dawood Sayed, Shivanand P Lad, David J DiBenedetto, Khalid A Sethi, Johnathan H Goree, Matthew T Bennett, Nathan J Harrison, Atef F Israel, Paul Chang, Paul W Wu, Gennady Gekht, Charles E Argoff, Christian E Nasr, Rod S Taylor, Jeyakumar Subbaroyan, Bradford E Gliner, David L Caraway, and Nagy A Mekhail

Integrated Personal Omics Profiling for Obesity, Brian D. Piening

Maintaining operational excellence during the COVID-19 pandemic in the FLOW trial, RE Pratley, Katherine Tuttle, and See full list of authors in comments

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#26 Cardiorenal Protection with Newer Antidiabetic Agents, Janani Rangaswami, Vivek Bhalla, Katherine Tuttle, and Muthiah Vaduganathan

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Facebook Live: HMR Weight Management: Insights into Successful Weight Loss, Rick Riess and Frances Broyles

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Anti-GBM nephritis with mesangial IgA deposits after SARS-CoV-2 mRNA vaccination., Allan Sacker, Vanderlene Kung, and Nicole Andeen

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Association of Obesity with Cardiovascular Risk Factors and Kidney Disease Outcomes in Primary Proteinuric Glomerulopathies., Paras P Shah, Tammy M Brady, Kevin E C Meyers, Michelle M O'Shaughnessy, Keisha L Gibson, Tarak Srivastava, Jarcy Zee, Daniel Cattran, Katherine Tuttle, Crystal Gadegbeku, Dorey Glenn, Vimal Derebail, Abigail Smith, Chia-Shi Wang, Brenda W Gillespie, Markus Bitzer, and Christine B Sethna

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Association of Obesity with Cardiovascular Risk Factors and Kidney Disease Outcomes in Primary Proteinuric Glomerulopathies., Paras P Shah, Tammy M Brady, Kevin E C Meyers, Michelle M O'Shaughnessy, Keisha L Gibson, Tarak Srivastava, Jarcy Zee, Daniel Cattran, Katherine Tuttle, Crystal Gadegbeku, Dorey Glenn, Vimal Derebail, Abigail Smith, Chia-Shi Wang, Brenda W Gillespie, Markus Bitzer, and Christine B Sethna

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Albuminuria Testing in Hypertension and Diabetes: An Individual-Participant Data Meta-Analysis in a Global Consortium., Jung-Im Shin, Alex R Chang, Morgan E Grams, Josef Coresh, Shoshana H Ballew, Aditya Surapaneni, Kunihiro Matsushita, Henk J G Bilo, Juan J Carrero, Gabriel Chodick, Kenn B Daratha, Girish N Nadkarni, Robert G Nelson, Christoph Nowak, Nikita Stempniewicz, Keiichi Sumida, Jamie P Traynor, Mark Woodward, Yingying Sang, Ron T Gansevoort, and CKD Prognosis Consortium

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The case for early identification and intervention of chronic kidney disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference., Michael G Shlipak, Sri Lekha Tummalapalli, L Ebony Boulware, Morgan E Grams, Joachim H Ix, Vivekanand Jha, Andre-Pascal Kengne, Magdalena Madero, Borislava Mihaylova, Navdeep Tangri, Michael Cheung, Michel Jadoul, Wolfgang C Winkelmayer, Sophia Zoungas, Conference Participants, and Radica Alicic

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Esophageal Necrosis as an Unexpected Complication of Diabetic Ketoacidosis, Hayden Smith and Tricia James

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Pralsetinib for patients with advanced or metastatic RET-altered thyroid cancer (ARROW): a multi-cohort, open-label, registrational, phase 1/2 study., Vivek Subbiah, Mimi I Hu, Lori J Wirth, Martin Schuler, Aaron S Mansfield, Giuseppe Curigliano, Marcia S Brose, Viola W Zhu, Sophie Leboulleux, Daniel W Bowles, Christina S Baik, Douglas Adkins, Bhumsuk Keam, Ignacio Matos, Elena Garralda, Justin F Gainor, Gilberto Lopes, Chia-Chi Lin, Yann Godbert, Debashis Sarker, Stephen G Miller, Corinne Clifford, Hui Zhang, Christopher D Turner, and Matthew H Taylor

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Outcomes in robotic-assisted partial nephrectomy for imperative versus elective indications., J Tan, N Sathianathen, M Cumberbatch, P Dasgupta, A Mottrie, R Abaza, K H Rha, T B Yuvaraja, D J Parekh, U Capitanio, R Ahlawat, S Rawal, N M Buffi, A Sivaraman, K K Maes, G Gautham, F Porpiglia, L Turkeri, M Bhandari, B Challacombe, J Porter, C Rogers, and D Moon

Best of ASN Journals, Katherine Tuttle

Better Diabetes & CKD Care by Moving from Evidence to Practice, Katherine Tuttle

“Current state of breakthrough therapies for DKD”, Katherine Tuttle

Current Therapeutic Approaches for Diabetic Kidney Disease, Katherine Tuttle

Current Therapeutic Approaches for Diabetic Kidney Disease, Katherine Tuttle

Diabetes, Heart Failure and Chronic Kidney Disease: Diverting Traffic at a Dangerous Intersection, Katherine Tuttle

Emerging treatments and the role of GLP-1 RAs in CKD, Katherine Tuttle

Essential Drugs in Patients with Diabetic Kidney Disease, Katherine Tuttle

Heart and Kidney Benefits with GLP-1 Receptor Agonists: Where Do They Fit in the Therapeutic Armamentarium?, Katherine Tuttle

Managing Sodium-Glucose Cotransporter 2 Inhibitors with Other Diabetes Agents, Diuretics and Heart Failure Drugs, Katherine Tuttle

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Perspective; Finerenone shows HF benefit in mild to moderate diabetic kidney disease: FIGARO-DKD, Katherine Tuttle

Putting It Together: A Whole Person Approach to Diabetes, Katherine Tuttle

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SGLT2 inhibition and chronic kidney disease outcomes: in diabetes and beyond., Katherine Tuttle

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Therapeutic Transformation for Patients with Diabetes and CKD, Katherine Tuttle

Updates to Care: Diabetes and Kidney Disease, Katherine Tuttle

Upping the Game: Optimizing Medication Management in CKD, Katherine Tuttle

Who, What, and Where for Newer Drugs for Diabetic Kidney Disease, Katherine Tuttle

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Clinicopathological Characteristics of Adult Patients in the United States with Focal Segmental Glomerulosclerosis (FSGS), Katherine Tuttle, Clint Abner, Kerime Ararat, Patrick D. Walker, Amin Yakubu, and Martin C. Bunke

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Patient perspectives and involvement in precision medicine research., Katherine Tuttle, Jack Bebiak, Keith Brown, Catherine Campbell, Ashveena Dighe, Lynda Hyashi, Nichole Jefferson, Glenda V Roberts, Christy Stutzke, Richard Knight, and Kidney Precision Medicine Project

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Therapeutic transformation for diabetic kidney disease., Katherine Tuttle and David Z I Cherney

Contemporary CKD incidence rates in adults with diabetes by race/ethnicity, sex, and age, Katherine Tuttle, CR Jones, Kenn Daratha, Radica Alicic, and See full list of authors in comments

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Breaking New Ground with Incretin Therapy in Diabetes., Katherine R Tuttle

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Glycemic Variability and KIM-1-Induced Inflammation in the Diabetic Kidney., Katherine R Tuttle and Radica Z Alicic

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Clinical Outcomes by Albuminuria Status with Dulaglutide versus Insulin Glargine in Participants with Diabetes and CKD: AWARD-7 Exploratory Analysis., Katherine Tuttle, Brian Rayner, Mark C Lakshmanan, Anita Y M Kwan, Manige Konig, Linda Shurzinske, and Fady T Botros

Clinicopathological Characteristics of Adult Patients in the United States with Focal Segmental Glomerulosclerosis (FSGS), Katherine Tuttle and See full list of authors in comments

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Single stage Xi® robotic radical nephroureterectomy for upper tract urothelial carcinoma: surgical technique and outcomes., Alessandro Veccia, Umberto Carbonara, Ithaar Derweesh, Reza Mehrazin, James R Porter, Firas Abdollah, Elio Mazzone, Chandru P Sundaram, Mark Gonzalgo, Riccardo Mastroianni, Alireza Ghoreifi, Giovanni E Cacciamani, Devin Patel, Jamil Marcus, Alyssa Danno, James Steward, Amit S Bhattu, Aeen Asghar, Adam C Reese, Zhenjie Wu, Robert G Uzzo, Andrea Minervini, Koon H Rha, Matteo Ferro, Vitaly Margulis, Lance J Hampton, Giuseppe Simone, Daniel D Eun, Hooman Djaladat, Alexandre Mottrie, and Riccardo Autorino

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Safety and Efficacy of GFB-887, a TRPC5 Channel Inhibitor, in Patients With Focal Segmental Glomerulosclerosis, Treatment-Resistant Minimal Change Disease, or Diabetic Nephropathy: TRACTION-2 Trial Design., Liron Walsh, John F Reilly, Caitlin Cornwall, Gregory A Gaich, Debbie S Gipson, Hiddo J L Heerspink, Leslie Johnson, Howard Trachtman, Katherine Tuttle, Youssef M K Farag, Krishna Padmanabhan, Xin-Ru Pan-Zhou, James R Woodworth, and Frank S Czerwiec

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A Preoperative Nomogram to Predict Renal Function Insufficiency for Cisplatin-based Adjuvant Chemotherapy Following Minimally Invasive Radical Nephroureterectomy (ROBUUST Collaborative Group)., Zhenjie Wu, Qi Chen, Hooman Djaladat, Andrea Minervini, Robert G Uzzo, Chandru P Sundaram, Koon H Rha, Mark L Gonzalgo, Reza Mehrazin, Elio Mazzone, Jamil Marcus, Alyssa Danno, James R Porter, Aeen Asghar, Fady Ghali, Georgi Guruli, Antoin Douglawi, Giovanni Cacciamani, Alireza Ghoreifi, Giuseppe Simone, Vitaly Margulis, Matteo Ferro, Riccardo Tellini, Andrea Mari, Abhishek Srivastava, James Steward, Ali Al-Qathani, Ahmad Al-Mujalhem, Amit Satish Bhattu, Alexander Mottrie, Firas Abdollah, Daniel D Eun, Ithaar Derweesh, Alessandro Veccia, Riccardo Autorino, and Linhui Wang

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Autopopulus: A Novel Framework for Autoencoder Imputation on Large Clinical Datasets., Davina J Zamanzadeh, Panayiotis Petousis, Tyler A Davis, Susanne B Nicholas, Keith C Norris, Katherine Tuttle, Alex A T Bui, and Majid Sarrafzadeh

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APOL1 genotype-associated morphologic changes among patients with focal segmental glomerulosclerosis., Jarcy Zee, Michelle T McNulty, Jeffrey B Hodgin, Olga Zhdanova, Sangeeta Hingorani, Jonathan Ashley Jefferson, Keisha L Gibson, Howard Trachtman, Alessia Fornoni, Katherine M Dell, Heather N Reich, Serena Bagnasco, Larry A Greenbaum, Richard A Lafayette, Debbie S Gipson, Elizabeth Brown, Matthias Kretzler, Gerald Appel, Kamalanathan K Sambandam, Katherine Tuttle, Dhruti Chen, Meredith A Atkinson, Marie C Hogan, Frederick J Kaskel, Kevin E Meyers, John O'Toole, Tarak Srivastava, Christine B Sethna, Michelle A Hladunewich, J J Lin, Cynthia C Nast, Vimal K Derebail, Jiten Patel, Suzanne Vento, Lawrence B Holzman, Ambarish M Athavale, Sharon G Adler, Kevin V Lemley, John C Lieske, Jonathan J Hogan, Crystal A Gadegbeku, Fernando C Fervenza, Chia-Shi Wang, Raed Bou Matar, Pamela Singer, Jeffrey B Kopp, Laura Barisoni, and Matthew G Sampson