The Digestive Health Institute is a network of highly trained doctors and surgeons who treat disorders of the gastrointestinal (GI) tract, as well as the liver, gallbladder and pancreas. As it becomes increasingly complex to treat digestive diseases and GI cancer, optimizing care relies more on the close collaboration of experts from across disciplines.

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Submissions from 2018

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Discussion of "Sarcopenia is not associated with morbidity, mortality, or recurrence after esophagectomy for cancer"., Ralph W. Aye MD

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Laparoscopic magnetic sphincter augmentation versus double-dose proton pump inhibitors for management of moderate-to-severe regurgitation in GERD: a randomized controlled trial., R C Bell, J C Lipham, B E Louie, V A Williams, J D Luketich, M A Hill, W O Richards, C M Dunst, D G Lister, L E McDowell-Jacobs, P R Reardon, K L Woods, J C Gould, F Buckley, S N Kothari, L Khaitan, C D Smith, A Park, C C Smith, G R Jacobsen, G Abbas, and P O Katz

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Research priorities for the discovery of a cure for chronic hepatitis B: Report of a workshop., Timothy M Block, Harvey Alter, Nathaniel Brown, Alan Brownstein, Carol Brosgart, Kyong-Mi Chang, Pei-Jer Chen, Chari Cohen, Hashem El-Serag, Jordan Feld, Robert Gish, Jeffrey Glenn, Tim F Greten, Juo-Tao Guo, Yujin Hoshida, Kris V Kowdley, Wenhui Li, Anna S Lok, Brian McMahon, Anand Mehta, Robert Perrillo, Charles M Rice, JoAnn Rinaudo, Raymond F Schinazi, and Kirti Shetty

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Antibiotic Utilization Before Endourological Surgery for Urolithiasis: Endourological Society Survey Results., Evan C Carlos, Ramy F Youssef, Adam G Kaplan, Daniel A Wollin, Brent B Winship, Brian H Eisner, Roger L Sur, Glenn M Preminger, and Michael E Lipkin

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Relationship Between Three Commonly Used Non-invasive Fibrosis Biomarkers and Improvement in Fibrosis Stage in Patients With NASH., Naga Chalasani, Manal F Abdelmalek, Rohit Loomba, Kris V Kowdley, Arthur J McCullough, Srinivasan Dasarathy, Brent A Neuschwander-Tetri, Norah Terrault, Beatrice Ferguson, Reshma Shringarpure, David Shapiro, and Arun J Sanyal

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Histopathology of locally advanced colorectal carcinoma, with emphasis on tumor invasion of adherent peritoneal membranes., Jey-Hsin Chen

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Hepatitis C virus re-treatment in the era of direct-acting antivirals: projections in the USA., J Chhatwal, Q Chen, T Ayer, E D Bethea, F Kanwal, K V Kowdley, X Wang, M S Roberts, and S C Gordon

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Rates of Prevalent Colorectal Cancer Occurrence in Persons 75 Years of Age and Older: A Population-Based National Study., Vijit Chouhan, Emad Mansoor, Sravanthi Parasa, and Gregory S Cooper

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Prediagnostic circulating markers of inflammation and risk of oesophageal adenocarcinoma: a study within the National Cancer Institute Cohort Consortium., Michael B Cook, Matthew J Barnett, Cathryn H Bock, Amanda J Cross, Phyllis J Goodman, Gary E Goodman, Christopher A Haiman, Kay-Tee Khaw, Marjorie L McCullough, Christine C Newton, Marie-Christine Boutron-Ruault, Eiliv Lund, Martin Rutegård, Mark D Thornquist, Michael Spriggs, Carol Giffen, Neal D Freedman, Troy Kemp, Candyce H Kroenke, Loïc Le Marchand, Jin Young Park, Michael Simon, Lynne R Wilkens, Ligia Pinto, Allan Hildesheim, and Peter T Campbell

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Macrophage-derived IL-1β/NF-κB signaling mediates parenteral nutrition-associated cholestasis., Karim C El Kasmi, Padade M Vue, Aimee L Anderson, Michael W Devereaux, Swati Ghosh, Natarajan Balasubramaniyan, Sophie A Fillon, Carola Dahrenmoeller, Ayed Allawzi, Crystal Woods, Sarah McKenna, Clyde J Wright, Linda Johnson, Angelo D'Alessandro, Julie A Reisz, Eva Nozik-Grayck, Frederick J Suchy, and Ronald J Sokol

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The Negative Impact of Body Mass Index on the Tumor Microenvironment in Colon Cancer: Results of a Prospective Trial., Devin C Flaherty, John R Jalas, Myung S Sim, Alexander Stojadinovic, Mladjan Protic, Delphine J Lee, and Anton J Bilchik

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A randomized, placebo-controlled trial of cenicriviroc for treatment of nonalcoholic steatohepatitis with fibrosis., Scott L Friedman, Vlad Ratziu, Stephen A Harrison, Manal F Abdelmalek, Guruprasad P Aithal, Juan Caballeria, Sven Francque, Geoffrey Farrell, Kris V Kowdley, Antonio Craxi, Krzysztof Simon, Laurent Fischer, Liza Melchor-Khan, Jeffrey Vest, Brian L Wiens, Pamela Vig, Star Seyedkazemi, Zachary Goodman, Vincent Wai-Sun Wong, Rohit Loomba, Frank Tacke, Arun Sanyal, and Eric Lefebvre

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Lower Annual Rate of Progression of Short-Segment vs Long-Segment Barrett's Esophagus to Esophageal Adenocarcinoma., Nour Hamade, Sreekar Vennelaganti, Sravanthi Parasa, Prashanth Vennalaganti, Srinivas Gaddam, Manon C W Spaander, Sophie H van Olphen, Prashanthi N Thota, Kevin F Kennedy, Marco J Bruno, John J Vargo, Sharad Mathur, Brooks D Cash, Richard Sampliner, Neil Gupta, Gary W Falk, Ajay Bansal, Patrick E Young, David A Lieberman, and Prateek Sharma

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Chronic Hepatitis C in Elderly Patients: Current Evidence with Direct-Acting Antivirals., Manan A Jhaveri, Vignan Manne, and Kris V Kowdley

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Does the implementation of a pediatric appendicitis pathway promoting ultrasound work outside of a children's hospital?, Emily Kobayashi, Bennett Johnson, Kathleen Goetz, James Scanlan, and Robert Weinsheimer

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A randomized trial of obeticholic acid monotherapy in patients with primary biliary cholangitis., Kris V Kowdley, Velimir Luketic, Roger Chapman, Gideon M Hirschfield, Raoul Poupon, Christoph Schramm, Catherine Vincent, Christian Rust, Albert Parés, Andrew Mason, Hanns-Ulrich Marschall, David Shapiro, Luciano Adorini, Cathi Sciacca, Tessa Beecher-Jones, Olaf Böhm, Richard Pencek, and David Jones

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Outcomes of Early Liver Transplantation for Patients With Severe Alcoholic Hepatitis., Brian P Lee, Neil Mehta, Laura Platt, Ahmet Gurakar, John P Rice, Michael R Lucey, Gene Y Im, George Therapondos, Hyosun Han, David W Victor, Oren K Fix, Lisanne Dinges, Deepti Dronamraju, Christine Hsu, Michael D Voigt, Mary E Rinella, Haripriya Maddur, Sheila Eswaran, Jessica Hause, David Foley, R Mark Ghobrial, Jennifer L Dodge, Zhiping Li, and Norah A Terrault

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Transversus Abdominis Plane Block Improves Perioperative Outcome After Esophagectomy Versus Epidural., Gal Levy, Mark A Cordes, Alexander S Farivar, Ralph W Aye, and Brian E Louie

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Reply., Gal Levy, Katherine Haeck, and Brian E Louie

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Cardiac MRI T2* in Liver Transplant Candidates: Application and Performance of a Novel Imaging Technique to Identify Patients at Risk for Poor Posttransplant Cardiac Outcomes., Sara M Lewin, Kimberly Kallianos, M Ilan Nevah, Susan Zhao, Oren K Fix, Gabriel C Brooks, Teresa De Marco, Atif N Qasim, Karen G Ordovas, and Neil Mehta

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Comparative Molecular Analysis of Gastrointestinal Adenocarcinomas., Yang Liu, Nilay S Sethi, Toshinori Hinoue, Barbara G Schneider, Andrew D Cherniack, Francisco Sanchez-Vega, Jose A Seoane, Farshad Farshidfar, Reanne Bowlby, Mirazul Islam, Jaegil Kim, Walid Chatila, Rehan Akbani, Rupa S Kanchi, Charles S Rabkin, Joseph E Willis, Kenneth K Wang, Shannon J McCall, Lopa Mishra, Akinyemi I Ojesina, Susan Bullman, Chandra Sekhar Pedamallu, Alexander J Lazar, Ryo Sakai, Vésteinn Thorsson, Adam J Bass, and Peter W Laird

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Factors Associated with Histologic Response in Adult Patients with Nonalcoholic Steatohepatitis., Rohit Loomba, Arun J Sanyal, Kris V Kowdley, Norah Terrault, Naga P Chalasani, Manal F Abdelmalek, Arthur J McCullough, Reshma Shringarpure, Beatrice Ferguson, Lois Lee, Jianfen Chen, Alexander Liberman, David Shapiro, and Brent A Neuschwander-Tetri

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Pathophysiology of Nonalcoholic Fatty Liver Disease/Nonalcoholic Steatohepatitis., Vignan Manne, Priya Handa, and Kris V Kowdley

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Human Gut Microbiota and Gastrointestinal Cancer., Changting Meng, Chunmei Bai, Thomas D Brown, Leroy E Hood, and Qiang Tian

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Milder disease stage in patients with primary biliary cholangitis over a 44-year period: A changing natural history., Carla F Murillo Perez, Jorn C Goet, Willem J Lammers, Aliya Gulamhusein, Henk R van Buuren, Cyriel Y Ponsioen, Marco Carbone, Andrew Mason, Christophe Corpechot, Pietro Invernizzi, Marlyn J Mayo, Pier Maria Battezzati, Annarosa Floreani, Albert Pares, Frederik Nevens, Kris V Kowdley, Tony Bruns, George N Dalekos, Douglas Thorburn, Gideon Hirschfield, Nicholas F LaRusso, Keith D Lindor, Kalliopi Zachou, Raoul Poupon, Palak J Trivedi, Xavier Verhelst, Harry L A Janssen, and Bettina E Hansen

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Resectable Distal Pancreas Cancer: Time to Reconsider the Role of Upfront Surgery., Daniel W Nelson, Shu-Ching Chang, Gary Grunkemeier, Ahmed N Dehal, David Y Lee, Trevan D Fischer, L Andrew DiFronzo, and Victoria V O'Connor

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Review of prolonged care services codes., Jill Olmstead

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Understanding the importance of diagnosis coding., Jill Olmstead

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International validation of the consensus Immunoscore for the classification of colon cancer: a prognostic and accuracy study., Franck Pagès, Bernhard Mlecnik, Florence Marliot, Gabriela Bindea, Fang-Shu Ou, Carlo Bifulco, Alessandro Lugli, Inti Zlobec, Tilman T Rau, Martin D Berger, Iris D Nagtegaal, Elisa Vink-Börger, Arndt Hartmann, Carol Geppert, Julie Kolwelter, Susanne Merkel, Robert Grützmann, Marc Van den Eynde, Anne Jouret-Mourin, Alex Kartheuser, Daniel Léonard, Christophe Remue, Julia Y Wang, Prashant Bavi, Michael H A Roehrl, Pamela S Ohashi, Linh T Nguyen, SeongJun Han, Heather L MacGregor, Sara Hafezi-Bakhtiari, Bradly G Wouters, Giuseppe V Masucci, Emilia K Andersson, Eva Zavadova, Michal Vocka, Jan Spacek, Lubos Petruzelka, Bohuslav Konopasek, Pavel Dundr, Helena Skalova, Kristyna Nemejcova, Gerardo Botti, Fabiana Tatangelo, Paolo Delrio, Gennaro Ciliberto, Michele Maio, Luigi Laghi, Fabio Grizzi, Tessa Fredriksen, Bénédicte Buttard, Mihaela Angelova, Angela Vasaturo, Pauline Maby, Sarah E Church, Helen K Angell, Lucie Lafontaine, Daniela Bruni, Carine El Sissy, Nacilla Haicheur, Amos Kirilovsky, Anne Berger, Christine Lagorce, Jeffrey P Meyers, Christopher Paustian, Zipei Feng, Carmen Ballesteros-Merino, Jeroen Dijkstra, Carlijn van de Water, Shannon van Lent-van Vliet, Nikki Knijn, Ana-Maria Mușină, Dragos-Viorel Scripcariu, Boryana Popivanova, Mingli Xu, Tomonobu Fujita, Shoichi Hazama, Nobuaki Suzuki, Hiroaki Nagano, Kiyotaka Okuno, Toshihiko Torigoe, Noriyuki Sato, Tomohisa Furuhata, Ichiro Takemasa, Kyogo Itoh, Prabhu S Patel, Hemangini H Vora, Birva Shah, Jayendrakumar B Patel, Kruti N Rajvik, Shashank J Pandya, Shilin N Shukla, Yili Wang, Guanjun Zhang, Yutaka Kawakami, Francesco M Marincola, Paolo A Ascierto, Daniel J Sargent, Bernard A Fox, and Jérôme Galon

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Upper and Lower Gastrointestinal Endoscopic Findings in HIV-Infected Patients in the Era of Highly Active Antiretroviral Therapy., Russell Parvin, Sindhura Kolli, Jamil Shah, Manan Jhaveri, and Madhavi Reddy

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Reviewing the Risk of Colorectal Cancer in Inflammatory Bowel Disease After Liver Trasnplantation for Primary Sclerosing Cholangitis., Bhavana Bhagya Rao, Bret Lashner, and Kris V Kowdley

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Hiatal hernia recurrence following magnetic sphincter augmentation and posterior cruroplasty: intermediate-term outcomes., Kais A Rona, James M Tatum, Joerg Zehetner, Katrin Schwameis, Carol Chow, Kamran Samakar, Adrian Dobrowolsky, Caitlin C Houghton, Nikolai Bildzukewicz, and John C Lipham

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No impact of resistance-associated substitutions on the efficacy of sofosbuvir, velpatasvir, and voxilaprevir for 12 weeks in HCV DAA-experienced patients., Christoph Sarrazin, Curtis L Cooper, Michael P Manns, K Rajender Reddy, Kris V Kowdley, Stuart K Roberts, Hadas Dvory-Sobol, Evguenia Svarovskia, Ross Martin, Gregory Camus, Brian P Doehle, Luisa M Stamm, Robert H Hyland, Diana M Brainard, Hongmei Mo, Stuart C Gordon, Marc Bourliere, Stefan Zeuzem, and Steven L Flamm

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The role of laparoscopic Nissen, Hill, and Nissen-Hill hybrid repairs for uncomplicated gastroesophageal reflux disease., Ealaf Shemmeri and Ralph W Aye

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Vibration-controlled Transient Elastography to Assess Fibrosis and Steatosis in Patients With Nonalcoholic Fatty Liver Disease., Mohammad S Siddiqui, Raj Vuppalanchi, Mark L Van Natta, Erin Hallinan, Kris V Kowdley, Manal Abdelmalek, Brent A Neuschwander-Tetri, Rohit Loomba, Srinivasan Dasarathy, Danielle Brandman, Edward Doo, James A Tonascia, David E Kleiner, Naga Chalasani, and Arun J Sanyal

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Association of Immunologic Markers With Survival in Upfront Resectable Pancreatic Cancer., Ephraim S Tang, Philippa H Newell, Ronald F Wolf, Paul Daniel Hansen, Benjamin Cottam, Carmen Ballesteros-Merino, and Michael J Gough

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Clinical outcomes five years after POEM for treatment of primary esophageal motility disorders., Ezra N Teitelbaum, Christy M Dunst, Kevin M Reavis, Ahmed M Sharata, Marc A Ward, Steven R DeMeester, and Lee L Swanström

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Extracorporeal cellular therapy (ELAD) in severe alcoholic hepatitis: A multinational, prospective, controlled, randomized trial., Julie Thompson, Natasha Jones, Ali Al-Khafaji, Shahid Malik, David Reich, Santiago Munoz, Ross MacNicholas, Tarek Hassanein, Lewis Teperman, Lance Stein, Andrés Duarte-Rojo, Raza Malik, Talal Adhami, Sumeet Asrani, Nikunj Shah, Paul Gaglio, Anupama Duddempudi, Brian Borg, Rajiv Jalan, Robert Brown, Heather Patton, Rohit Satoskar, Simona Rossi, Amay Parikh, Ahmed ElSharkawy, Parvez Mantry, Linda Sher, David Wolf, Marquis Hart, Charles Landis, Alan Wigg, Shahid Habib, Geoffrey McCaughan, Steven Colquhoun, Alyssa Henry, Patricia Bedard, Lee Landeen, Michael Millis, Robert Ashley, William Frank, Andrew Henry, Jan Stange, and Ram Subramanian

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Su1776 - Superior Survival of South and East Asians with Colorectal Carcinoma in the United States, Abhineet Uppal, Ramkishen Narayanan, Shu-Ching Chang, Trevan Fischer, and Melanie Goldfarb

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A randomized controlled trial: does coaching using video during direct laryngoscopy improve residents' success in neonatal intubations?, Sarah Volz, Timothy P Stevens, and Rita Dadiz

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What Are the Most Significant Cost and Value Drivers for Pancreatic Resection in an Integrated Healthcare System?, Brooke Vuong, Ahmed N Dehal, Abhineet Uppal, Stacey L Stern, Juan Mejia, Roshanthi Weerasinghe, Vandana Kapoor, Evan Ong, Paul D Hansen, and Anton J Bilchik

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Performance characteristics of vibration-controlled transient elastography for evaluation of nonalcoholic fatty liver disease., Raj Vuppalanchi, Mohammad S Siddiqui, Mark L Van Natta, Erin Hallinan, Danielle Brandman, Kris Kowdley, Brent A Neuschwander-Tetri, Rohit Loomba, Srinivas Dasarathy, Manal Abdelmalek, Edward Doo, James A Tonascia, David E Kleiner, Arun J Sanyal, and Naga Chalasani

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Resection of the largest reported hepatic small vessel neoplasm., Sarah Walcott-Sapp, Ephraim Tang, Sanjay Kakar, Jian Shen, and Paul Hansen

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Endoscopic resection of giant fibrovascular esophageal polyps., Marc A Ward, Kristin W Beard, Ezra N Teitelbaum, Ahmed M Sharata, Christy M Dunst, Lee L Swanstrom, and Kevin M Reavis

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Impedance-pH monitoring on medications does not reliably confirm the presence of gastroesophageal reflux disease in patients referred for antireflux surgery., Marc A Ward, Christy M Dunst, Ezra N Teitelbaum, Valerie J Halpin, Kevin M Reavis, Lee L Swanström, and Steven R DeMeester

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Factors influencing the outcome of magnetic sphincter augmentation for chronic gastroesophageal reflux disease., Heather F Warren, Lisa M Brown, Matias Mihura, Alexander S Farivar, Ralph W Aye, and Brian E Louie

Submissions from 2017

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Cap-assisted necrosectomy: a novel technique increasing safety and efficiency., Nishant Puri and Robin A Graham

Submissions from 2013

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Complications of gastro-oesophageal reflux disease., Sravanthi Parasa and P Sharma