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Submissions from 2019

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Addressing current challenges and future directions in immuno-oncology: expert perspectives from the 2017 NIBIT Foundation Think Tank, Siena, Italy., Michele Maio, George Coukos, Soldano Ferrone, Bernard A Fox, Wolf H Fridman, Patrick L Garcia, Michael Lahn, Olivier Provendier, Vincenzo Russo, Dominik Rüttinger, Aiman Shalabi, Zlatko Trajanoski, Jean Viallet, Jedd D Wolchok, and Ramy Ibrahim

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Immunotherapy for Head and Neck Cancer., Felix Sim, Rom Leidner, and Richard Bryan Bell

Submissions from 2018

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Clinical Development of Novel Drug-Radiotherapy Combinations., Saif S Ahmad, Marka R Crittenden, Phuoc T Tran, Paul G Kluetz, Gideon M Blumenthal, Helen Bulbeck, Richard D Baird, Kaye J Williams, Tim Illidge, Stephen M Hahn, Theodore S Lawrence, Patricia A Spears, Amanda J Walker, and Ricky A Sharma

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Amplifying IFN-γ Signaling in Dendritic Cells by CD11c-Specific Loss of SOCS1 Increases Innate Immunity to Infection while Decreasing Adaptive Immunity., Alejandro F Alice, Gwen Kramer, Shelly Bambina, Jason R Baird, Keith S Bahjat, Michael J Gough, and Marka R Crittenden

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Perspectives in immunotherapy: meeting report from the Immunotherapy Bridge (29-30 November, 2017, Naples, Italy)., Paolo A Ascierto, James Brugarolas, Luigi Buonaguro, Lisa H Butterfield, David Carbone, Bruno Daniele, Robert Ferris, Bernard A Fox, Jérôme Galon, Cesare Gridelli, Howard L Kaufman, Christopher A Klebanoff, Ignacio Melero, Paul Nathan, Chrystal M Paulos, Marco Ruella, Ryan Sullivan, Hassane Zarour, and Igor Puzanov

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Perspectives in melanoma: Meeting report from the Melanoma Bridge (30 November-2 December, 2017, Naples, Italy)., Paolo A Ascierto, Igor Puzanov, Sanjiv S Agarwala, Carlo Bifulco, Gerardo Botti, Corrado Caracò, Gennaro Ciliberto, Michael A Davies, Reinhard Dummer, Soldano Ferrone, Thomas F Gajewski, Claus Garbe, Jason J Luke, Francesco M Marincola, Giuseppe Masucci, Janice M Mehnert, Nicola Mozzillo, Giuseppe Palmieri, Michael A Postow, Stephen P Schoenberger, Ena Wang, and Magdalena Thurin

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MV-626, a potent and selective inhibitor of ENPP1 enhances STING activation and augments T-cell mediated anti-tumor activity in vivo, Jason Baird, Gregory Dietsch, Vincent Florio, Michael Gallatin, Clayton Knox, Joshua Odingo, Marka Crittenden, and Michael J. Gough

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Evaluation of explant responses to STING ligands: personalized immunosurgical therapy for head and neck squamous cell carcinoma., Jason R Baird, R Bryan Bell, Victoria Troesch, David J Friedman, Shelly Bambina, Gwen Kramer, Tiffany Blair, Terry R Medler, Yaping Wu, Zhaoyu Sun, Tanja D de Gruijl, Rieneke van de Ven, Rom Leidner, Marka R Crittenden, and Michael J. Gough

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Integrative spatially-resolved, high-plex digital profiling enables characterization of complex immune biology in the tumor microenvironment of mesothelioma, Carmen Ballesteros-Merino, Moritz Widmaier, Sarah Church, Thomas Herz, Alexei Budco, Das Medrikova, Ivan Kanchev, Andrew White, Douglas Hinerfeld, Shawn Jensen, John Handy, Rachel Sanborn, Carlo Bifulco, Sarah Warren, Joseph Beechem, and Bernard .. Fox

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SITC 2018 workshop report: Immuno-Oncology Biomarkers: State of the Art., Lisa H Butterfield, Mary L Disis, Bernard A Fox, David R Kaufman, Samir N Khleif, and Ena Wang

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A Phase II Study of Celecoxib With Irinotecan, 5-Fluorouracil, and Leucovorin in Patients With Previously Untreated Advanced or Metastatic Colorectal Cancer., Emerson Y Chen, Charles D Blanke, Daniel G Haller, Al B Benson, Tomislav Dragovich, Heinz-Josef Lenz, Carlos Robles, Hong Li, Motomi Mori, Nora Mattek, Rachel E Sanborn, and Charles D Lopez

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Blocking immunoinhibitory receptor LILRB2 reprograms tumor-associated myeloid cells and promotes antitumor immunity., Hui-Ming Chen, William van der Touw, Yuan Shuo Wang, Kyeongah Kang, Sunny Mai, Jilu Zhang, Dayanira Alsina-Beauchamp, James A Duty, Sathish Kumar Mungamuri, Bin Zhang, Thomas Moran, Richard Flavell, Stuart Aaronson, Hong-Ming Hu, Hisashi Arase, Suresh Ramanathan, Raja Flores, Ping-Ying Pan, and Shu-Hsia Chen

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Phase IIIb safety results from an expanded-access protocol of talimogene laherparepvec for patients with unresected, stage IIIB-IVM1c melanoma., Jason Chesney, Sanjay Awasthi, Brendan Curti, Laura Hutchins, Gerald Linette, Pierre Triozzi, Marcus C B Tan, Russell E Brown, John Nemunaitis, Eric Whitman, Christopher Windham, Jose Lutzky, Gerald F Downey, Nicolas Batty, and Thomas Amatruda

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A multi-center phase II study of high dose interleukin-2 sequenced with vemurafenib in patients with BRAF-V600 mutation positive metastatic melanoma., Joseph I Clark, Jatinder Singh, Marc S Ernstoff, Christopher D Lao, Lawrence E Flaherty, Theodore F Logan, Brendan Curti, Sanjiv S Agarwala, Bret Taback, Lee Cranmer, Jose Lutzky, Theresa L Luna, Sandra Aung, and David H Lawson

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Implementation and Validation of an Automated Flow Cytometry Analysis Pipeline for Human Immune Profiling., Valerie Conrad, Christopher Dubay, Mehrnoush Malek, Ryan R Brinkman, Yoshinobu Koguchi, and William L. Redmond

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Delayed immune-related events after discontinuation of immunotherapy – DIRE syndrome?, Marcus Couey, R. Bryan Bell, Ashish Patel, Marka R Crittenden, Brendan Curti, and Rom Leidner

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Tumor cure by radiation therapy and checkpoint inhibitors depends on pre-existing immunity., Marka R Crittenden, Lauren Zebertavage, Gwen Kramer, Shelly Bambina, David Friedman, Victoria Troesch, Tiffany Blair, Jason R Baird, Alejandro F Alice, and Michael J Gough

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Immunotherapy in Advanced Renal Cancer - Is Cure Possible?, Brendan D Curti

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Polyethyleneimine modification of aluminum hydroxide nanoparticle enhances antigen transportation and cross-presentation of dendritic cells., Heng Dong, Zhi-Fa Wen, Lin Chen, Na Zhou, Hui Liu, Shiling Dong, Hong-Ming Hu, and Yongbin Mou

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Co-expression of CD39 and CD103 identifies tumor-reactive CD8 T cells in human solid tumors., Thomas Duhen, Rebekka Duhen, Ryan Montler, Jake Moses, Tarsem Moudgil, Noel F de Miranda, Cheri P Goodall, Tiffany C Blair, Bernard A Fox, Jason E McDermott, Shu-Ching Chang, Gary Grunkemeier, Rom Leidner, Richard Bryan Bell, and Andrew D Weinberg

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Earle A. Chiles Research Institute 2017 Year In Review, Earle A. Chiles Research Institute

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Overcoming Tumor-Induced Immune Suppression: From Relieving Inhibition to Providing Costimulation with T Cell Agonists., Dana A Emerson and William L Redmond

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The role of Galectin-3 in modulating tumor growth and immunosuppression within the tumor microenvironment., Mohammad Farhad, Annah S Rolig, and William L Redmond

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Tumor cell-released autophagosomes (TRAP) enhance apoptosis and immunosuppressive functions of neutrophils., Rong Gao, Jie Ma, Zhifa Wen, Peiying Yang, Jinjin Zhao, Meng Xue, Yongqiang Chen, Mohanad Aldarouish, Hong-Ming Hu, Xue-Jun Zhu, Ning Pan, and Li-Xin Wang

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Randomized phase III study of docetaxel plus bavituximab in previously treated advanced non-squamous non-small-cell lung cancer., D E Gerber, L Horn, M Boyer, Rachel E Sanborn, R Natale, R Palmero, P Bidoli, I Bondarenko, P Germonpre, D Ghizdavescu, A Kotsakis, H Lena, G Losonczy, K Park, W-C Su, M Tang, J Lai, N L Kallinteris, J S Shan, M Reck, and D R Spigel

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A Placebo-Controlled Phase II Study of Ruxolitinib in Combination With Pemetrexed and Cisplatin for First-Line Treatment of Patients With Advanced Nonsquamous Non-Small-Cell Lung Cancer and Systemic Inflammation., Giuseppe Giaccone, Rachel E Sanborn, Saiama N Waqar, Alex Martinez-Marti, Santiago Ponce, Huiling Zhen, Gerard Kennealey, Susan Erickson-Viitanen, and Eric Schaefer

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Inducible T cell Co-stimulator (ICOS) is upregulated on lymphocytes following radiation of tumors and ICOS agonism in combination with radiation results in enhanced tumor control, Michael J. Gough, Shelly Bambina, Monica Gostissa, Christopher Harvey, David Friedman, and Marka R Crittenden

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Aberrant Lck Signal via CD28 Costimulation Augments Antigen-Specific Functionality and Tumor Control by Redirected T Cells with PD-1 Blockade in Humanized Mice., Pratiksha Gulati, Julia Rühl, Abhilash Kannan, Magdalena Pircher, Petra Schuberth, Katarzyna J Nytko, Martin Pruschy, Simon Sulser, Mark Haefner, Shawn Jensen, Alex Soltermann, Wolfgang Jungraithmayr, Maya Eisenring, Thomas Winder, Panagiotis Samaras, Annett Tabor, Rene Stenger, Roger Stupp, Walter Weder, Christoph Renner, Christian Münz, and Ulf Petrausch

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Exploring optimal sequencing of radiation and immunotherapy combinations., Andrew J Gunderson and Kristina H Young

Where's the Money? Revenues associated with 3000 Lung Cancer Screens, John Handy Jr., Courtney Wood, Erika Rauch, Kevin Olson, Roshanthi Weerasinghe, Rachel Sanborn, and Micheal Skokan

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Ensartinib (X-396) in ALK-Positive Non-Small Cell Lung Cancer: Results from a First-in-Human Phase I/II, Multicenter Study., Leora Horn, Jeffrey R Infante, Karen L Reckamp, George R Blumenschein, Ticiana A Leal, Saiama N Waqar, Barbara J Gitlitz, Rachel E Sanborn, Jennifer G Whisenant, Liping Du, Joel W Neal, Jon P Gockerman, Gary Dukart, Kimberly Harrow, Chris Liang, James J Gibbons, Allison Holzhausen, Christine M Lovly, and Heather A Wakelee

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Single cell sequencing to identify TCRs that recognize autologous tumor cells after vaccination with allogeinic DRibble vaccine, Hong-Ming Hu, Christopher C. Paustian, Zhifa Wen, Tarsem L. Moudgil, Traci L. Hilton, Sam Bookhardt, Guangjie Yu, Eric Tran, Venkatesh Rajamanickam, Walter Urba, Rachel E. Sanborn, and Bernard A. Fox

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Coordinated responses to individual tumor antigens by IgG antibody and CD8+ T cells following cancer vaccination., Tyler W Hulett, Shawn M. Jensen, Phillip A Wilmarth, Ashok P Reddy, Carmen Ballesteros-Merino, Michael E Afentoulis, Christopher Dubay, Larry L David, and Bernard A Fox

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Pegzilarginase in combination with agonist anti-OX40 therapy enhances T cell priming and effector function leading to improved tumor regression and survival, Melissa Kasiewicz, Annah Rolig, Elizabeth Sturgill, Mark Badeaux, Scott Rowlinson, and William L. Redmond

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The Biaxial Double-Barrel Fibula Flap-A Simplified Technique for Fibula Maxillary Reconstruction., Baber Khatib, Ashish Patel, Eric J Dierks, R Bryan Bell, and Allen Cheng

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Novel frontiers in detecting cancer metastasis., Stanley P Leong, Carmen Ballesteros-Merino, Shawn M Jensen, Sebastian Marwitz, Carlo Bifulco, Bernard A Fox, and Mojca Skoberne

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SPIO Enhance the Cross-Presentation and Migration of DCs and Anionic SPIO Influence the Nanoadjuvant Effects Related to Interleukin-1β., Hui Liu, Heng Dong, Na Zhou, Shiling Dong, Lin Chen, Yanxiang Zhu, Hong-Ming Hu, and Yongbin Mou

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Open-source digital image analysis of whole-slide multiplex immunohistochemistry, Nikhil Lonberg, Carmen Ballesteros-Merino, Shawn Jensen, and Bernard A Fox

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PD-L1 expression with immune-infiltrate evaluation and outcome prediction in melanoma patients treated with ipilimumab., Gabriele Madonna, Carmen Ballesteros-Merino, Zipei Feng, Carlo Bifulco, Mariaelena Capone, Diana Giannarelli, Domenico Mallardo, Ester Simeone, Antonio M Grimaldi, Corrado Caracò, Gerardo Botti, Bernard A Fox, and Paolo A Ascierto

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Starting the Fight in the Tumor: Expert Recommendations for the Development of Human Intratumoral Immunotherapy (HIT-IT)., A Marabelle, R Andtbacka, K Harrington, I Melero, R Leidner, T de Baere, C Robert, P A Ascierto, J-F Baurain, M Imperiale, S Rahimian, D Tersago, E Klumper, M Hendriks, R Kumar, M Stern, K Öhrling, C Massacesi, I Tchakov, A Tse, J-Y Douillard, J Tabernero, J Haanen, and J Brody

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Preliminary evaluation of a novel whole slide multispectral assessment of seven markers: Potential to minimize bias in the characterization of the tumor immune environment, Carmen Ballesteros Merino, Shawn Jensen, Carla Coltharp, Kristin Roman, Chichung Wang, Nikhil Lonberg, Sebastian Marwitz, Tarsem Moudgil, William Miller, William Redmond, Yoshinobu Koguchi, Carlo Bifulco, Clifford Hoyt, and Bernard A. Fox

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Monosomy 17 in potentially curable HER2-amplified breast cancer: prognostic and predictive impact., David B Page, Hannah Wen, Edi Brogi, Dana Dure, Dara Ross, Kateri J Spinelli, Sujata Patil, Larry Norton, Clifford Hudis, and Heather L McArthur

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Updated efficacy of first or second-line pembrolizumab plus in metastatic triple negative breast cancer and correlations with baseline lymphocyte and naïve CD4+ T-cell count, David Page, Joanna Pucilowska, Laura Bennetts, I Kim, Katherine Sanchez, Maritza Martel, Alison Conlin, Nikki Moxon, Staci Mellinger, Anupama Acheson, K Kemmer, Z Mitri, J Vuky, J Ahn, C Abaya, T Manigault, R Basho, Walter Urba, and HL McArthur

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International validation of the consensus Immunoscore for the classification of colon cancer: a prognostic and accuracy study., Franck Pagès, Bernhard Mlecnik, Florence Marliot, Gabriela Bindea, Fang-Shu Ou, Carlo Bifulco, Alessandro Lugli, Inti Zlobec, Tilman T Rau, Martin D Berger, Iris D Nagtegaal, Elisa Vink-Börger, Arndt Hartmann, Carol Geppert, Julie Kolwelter, Susanne Merkel, Robert Grützmann, Marc Van den Eynde, Anne Jouret-Mourin, Alex Kartheuser, Daniel Léonard, Christophe Remue, Julia Y Wang, Prashant Bavi, Michael H A Roehrl, Pamela S Ohashi, Linh T Nguyen, SeongJun Han, Heather L MacGregor, Sara Hafezi-Bakhtiari, Bradly G Wouters, Giuseppe V Masucci, Emilia K Andersson, Eva Zavadova, Michal Vocka, Jan Spacek, Lubos Petruzelka, Bohuslav Konopasek, Pavel Dundr, Helena Skalova, Kristyna Nemejcova, Gerardo Botti, Fabiana Tatangelo, Paolo Delrio, Gennaro Ciliberto, Michele Maio, Luigi Laghi, Fabio Grizzi, Tessa Fredriksen, Bénédicte Buttard, Mihaela Angelova, Angela Vasaturo, Pauline Maby, Sarah E Church, Helen K Angell, Lucie Lafontaine, Daniela Bruni, Carine El Sissy, Nacilla Haicheur, Amos Kirilovsky, Anne Berger, Christine Lagorce, Jeffrey P Meyers, Christopher Paustian, Zipei Feng, Carmen Ballesteros-Merino, Jeroen Dijkstra, Carlijn van de Water, Shannon van Lent-van Vliet, Nikki Knijn, Ana-Maria Mușină, Dragos-Viorel Scripcariu, Boryana Popivanova, Mingli Xu, Tomonobu Fujita, Shoichi Hazama, Nobuaki Suzuki, Hiroaki Nagano, Kiyotaka Okuno, Toshihiko Torigoe, Noriyuki Sato, Tomohisa Furuhata, Ichiro Takemasa, Kyogo Itoh, Prabhu S Patel, Hemangini H Vora, Birva Shah, Jayendrakumar B Patel, Kruti N Rajvik, Shashank J Pandya, Shilin N Shukla, Yili Wang, Guanjun Zhang, Yutaka Kawakami, Francesco M Marincola, Paolo A Ascierto, Daniel J Sargent, Bernard A Fox, and Jérôme Galon

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Efficacy and toxicity of therapy immediately after treatment with nivolumab in relapsed multiple myeloma., Matthew J Pianko, Samuel A Funt, David B Page, Deepika Cattry, Emma C Scott, Stephen M Ansell, Ivan M Borrello, Martin Gutierrez, Nikoletta Lendvai, Hani Hassoun, C Ola Landgren, and Alexander M Lesokhin

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New Clues to Human Longevity, Brian D. Piening

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Impact of Specimen Heterogeneity on Biomarkers in Repository Samples from Patients with Acute Myeloid Leukemia: A SWOG Report., Era L Pogosova-Agadjanyan, Anna Moseley, Megan Othus, Frederick R Appelbaum, Thomas R Chauncey, I-Ming L Chen, Harry P Erba, John E Godwin, Min Fang, Kenneth J Kopecky, Alan F List, Galina L Pogosov, Jerald P Radich, Cheryl L Willman, Brent L Wood, Soheil Meshinchi, and Derek L Stirewalt

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Late stage tumor regression after PD-L1 blockade with a concurrent OX40 agonist., Fanny Polesso, Andrew D Weinberg, and Amy E Moran

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Tumor infiltrating lymphocyte recruitment after peri-lymphatic IRX-2 cytokine immunotherapy in resectable breast cancer and head and neck carcinoma, Joanna Pucilowska, Venkatesh Rajamanickam, Nikki Moxon, Monil Shah, Maritza Martel, Alison Conlin, James E. Egan, and David B. Page

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Perilymphatic IRX-2 cytokine therapy to enhance tumor infiltrating lymphocytes and PD-L1 expression preceding curative-intent therapy in early stage breast cancer, Joanna Pucilowska, Venkatesh Rajamanickam, Katherine Sanchez, Valerie Conrad, Alison Conlin, Shagheyegh Aliabadi-Wahle, Shu-Ching Chang, Gary Grunkemeier, Nikki Moxon, Staci Mellinger, Maritza Martel, James Egan, Monil Shah, and David B Page

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In Defense of Lady Windermere Syndrome., Jerome M Reich

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Reservations Regarding Lung Cancer Screening Guidelines., Jerome M Reich

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The Curious Omission of Treatment as a Predictor of Pulmonary Sarcoidosis Mortality., Jerome M Reich

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Erratum to inequivalence of non-aggressiveness in clinically diagnosed lung cancers and overdiagnosis in lung cancer screening trials., Jerome M Reich and Jong S Kim

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NKTR-214 (CD122-biased agonist) and NKTR-262 (TLR7/8 agonist) combination treatment pairs local innate immune activation with systemic CD8+ T cell expansion to enhance anti-tumor immunity, Annah S. Rolig, Daniel Rose, Saul Kivimäe, Deborah Charych, Werner Rubas, Jonathan Zalevsky, and William L. Redmond

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MHC class I loaded ligands from breast cancer cell lines: A potential HLA-I-typed antigen collection., Dmitri V Rozanov, Nikita D Rozanov, Kami E Chiotti, Ashok Reddy, Phillip A Wilmarth, Larry L David, Seung W Cha, Sunghee Woo, Pavel Pevzner, Vineet Bafna, Gregory G Burrows, Juha K Rantala, Trevor Levin, Pavana Anur, Katie Johnson-Camacho, Shaadi Tabatabaei, Daniel J Munson, Tullia C Bruno, Jill E Slansky, John W Kappler, Naoto Hirano, Sebastian Boegel, Bernard A Fox, Colt Egelston, Diana L Simons, Grecia Jimenez, Peter P Lee, Joe W Gray, and Paul T Spellman

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The Epigenomic Landscape of Pituitary Adenomas Reveals Specific Alterations and Differentiates Among Acromegaly, Cushing's Disease and Endocrine-Inactive Subtypes., Matthew P Salomon, Xiaowen Wang, Diego M Marzese, Sandy C Hsu, Nellie Nelson, Xin Zhang, Chikako Matsuba, Yuki Takasumi, Carmen Ballesteros-Merino, Bernard A Fox, Garni Barkhoudarian, Daniel F Kelly, and Dave S B Hoon

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Preliminary results from a first-in-human phase 1 study of the CD40 agonist monoclonal antibody (mAb) CDX-1140, Rachel Sanborn, Michael S. Gordon, Mark O'Hara, Nina Bhardwaj, Yi He, Tracey Rawls, Tibor Keler, and Michael Yellin

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Combined anti-PD-1 and anti-LAG-3 checkpoint blockade enhances CD8+ TIL effector function while reducing Tregs leading to reduced immune suppression and improved overall survival, Elizabeth Sturgill, Courtney Mick, David Jenkins, Johanna Kaufmann, and William L. Redmond

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An update on the Society for Immunotherapy of Cancer consensus statement on tumor immunotherapy for the treatment of cutaneous melanoma: version 2.0., Ryan J Sullivan, Michael B Atkins, John M Kirkwood, Sanjiv S Agarwala, Joseph I Clark, Marc S Ernstoff, Leslie Fecher, Thomas F Gajewski, Brian Gastman, David H Lawson, Jose Lutzky, David F McDermott, Kim A Margolin, Janice M Mehnert, Anna C Pavlick, Jon M Richards, Krista M Rubin, William Sharfman, Steven Silverstein, Craig L Slingluff, Vernon K Sondak, Ahmad A Tarhini, John A Thompson, Walter J Urba, Richard L White, Eric D Whitman, F Stephen Hodi, and Howard L Kaufman

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Association of Immunologic Markers With Survival in Upfront Resectable Pancreatic Cancer., Ephraim S Tang, Philippa H Newell, Ronald F Wolf, Paul Daniel Hansen, Benjamin Cottam, Carmen Ballesteros-Merino, and Michael J Gough

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Tumor mutational burden is a determinant of immune-mediated survival in breast cancer., Alexandra Thomas, Eric D Routh, Ashok Pullikuth, Guangxu Jin, Jing Su, Jeff W Chou, Katherine A Hoadley, Cristin Print, Nick Knowlton, Michael A Black, Sandra Demaria, Ena Wang, Davide Bedognetti, Wendell D Jones, Gaurav A Mehta, Michael L Gatza, Charles M Perou, David B Page, Pierre Triozzi, and Lance D Miller

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Mertk is a therapeutic target in combination with radiation to promote adaptive immune tumor responses, Garth Tormoen, Jason R Baird, Gwen Kramer, Shelly Bambina, Marka R Crittenden, and Michael J. Gough

Role of the immunosuppressive microenvironment in immunotherapy., Garth W Tormoen, Marka R Crittenden, and Michael J. Gough

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Glatiramer Acetate Enhances Myeloid-Derived Suppressor Cell Function via Recognition of Paired Ig-like Receptor B., William van der Touw, Kyeongah Kang, Yi Luan, Ge Ma, Sunny Mai, Lihui Qin, Guanglin Bian, Ruihua Zhang, Sathish Kumar Mungamuri, Hong-Ming Hu, Cheng Cheng Zhang, Stuart A Aaronson, Marc Feldmann, Wen-Chin Yang, Shu-Hsia Chen, and Ping-Ying Pan

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Autophagosome-based strategy to monitor apparent tumor-specific CD8 T cells in patients with prostate cancer., Rieneke van de Ven, Traci L Hilton, Hong-Ming Hu, Christopher J Dubay, Daniel Haley, Christopher Paustian, Sachin Puri, Walter Urba, Brendan Curti, Sandra Aung, and Bernard A Fox

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Autophagosome-based strategy to monitor apparent tumor-specific CD8 T cells in patients with prostate cancer, Rieneke van de Ven, Traci L. Hilton, Hong-Ming Hu, Christopher J. Dubay, Daniel Haley, Christopher Paustian, Sachin Puri, Walter J. Urba, Brendan D. Curti, Sandra Aung, and Bernard A. Fox

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Tumor cell-released autophagosomes (TRAPs) promote immunosuppression through induction of M2-like macrophages with increased expression of PD-L1., Zhi-Fa Wen, Hongxiang Liu, Rong Gao, Meng Zhou, Jie Ma, Yue Zhang, Jinjin Zhao, Yongqiang Chen, Tianyu Zhang, Fang Huang, Ning Pan, Jinping Zhang, Bernard A Fox, Hong-Ming Hu, and Li-Xin Wang

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ALT-803, an IL-15 superagonist, in combination with nivolumab in patients with metastatic non-small cell lung cancer: a non-randomised, open-label, phase 1b trial., John M Wrangle, Vamsidhar Velcheti, Manish R Patel, Elizabeth Garrett-Mayer, Elizabeth G Hill, James G Ravenel, Jeffrey S Miller, Mohammad Farhad, Kate Anderton, Kathryn Lindsey, Michele Taffaro-Neskey, Carol Sherman, Samantha Suriano, Marzena Swiderska-Syn, Amy Sion, Joni Harris, Andie R Edwards, Julie A Rytlewski, Catherine M Sanders, Erik C Yusko, Mark D Robinson, Carsten Krieg, William L Redmond, Jack O Egan, Peter R Rhode, Emily K Jeng, Amy D Rock, Hing C Wong, and Mark P Rubinstein

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Whole-mount Confocal Microscopy for Adult Ear Skin: A Model System to Study Neuro-vascular Branching Morphogenesis and Immune Cell Distribution., Tomoko Yamazaki, Wenling Li, and Yoh-Suke Mukouyama

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Whole-Mount Adult Ear Skin Imaging Reveals Defective Neuro-Vascular Branching Morphogenesis in Obese and Type 2 Diabetic Mouse Models., Tomoko Yamazaki, Wenling Li, Ling Yang, Ping Li, Haiming Cao, Sei-Ichiro Motegi, Mark C Udey, Elise Bernhard, Takahisa Nakamura, and Yoh-Suke Mukouyama

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Tissue Specific Origin, Development, and Pathological Perspectives of Pericytes., Tomoko Yamazaki and Yoh-Suke Mukouyama

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Enhanced detection of neoantigen-reactive T cells targeting unique and shared oncogenes for personalized cancer immunotherapy., Rami Yossef, Eric Tran, Drew C Deniger, Alena Gros, Anna Pasetto, Maria R Parkhurst, Jared J Gartner, Todd D Prickett, Gal Cafri, Paul F Robbins, and Steven A Rosenberg

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Vx3-Functionalized Alumina Nanoparticles Assisted Enrichment of Ubiquitinated Proteins from Cancer Cells for Enhanced Cancer Immunotherapy., Jinjin Zhao, Ning Pan, Fang Huang, Mohanad Aldarouish, Zhifa Wen, Rong Gao, Yuye Zhang, Hong-Ming Hu, Yanfei Shen, and Li-Xin Wang

Submissions from 2016

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Earle A. Chiles Research Institute 2015 Year In Review, Earle A. Chiles Research Institute