Providence Center for Cardiovascular Analytics, Research + Data Science (CARDS) is dedicated to leveraging our data and research infrastructure to accelerate innovation and discovery in heart and vascular health for the betterment of patient care. To support Providence Heart Institute’s research and quality efforts, the CARDS center includes analytics, registries, biostatistics, publications, and clinical trials. CARDS investigates the treatments, technologies and processes that lead to the best patient outcomes in service to high-value cardiovascular care. CARDS conducts research ‘in the context of clinical practice’, asking and answering important questions that will shape patient care and influence how our health care delivery systems are organized. CARDS leverages Providence’s real-world health care experience to create new knowledge.

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Submissions from 2022

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Axillary transvalvular microaxial pump as extended bridge to transcatheter aortic valve replacement in cardiogenic shock with severe aortic stenosis., Jacob Abraham, Lian Wang, Vishesh Kumar, Eric B Kirker, and Kateri Spinelli

Controversial Debates in Pulmonary Hypertension. Invasive Hemodynamics are Essential for Risk Stratification in PAH (PRO), Sophia Airhart

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Drug-Drug Interactions With Paxlovid and Select CV Medications, Nicole Martin Bhave, Tyler J Gluckman, and Barbara S. Wiggins

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Temporal trends and predictors of surgical ablation for atrial fibrillation across a multistate healthcare system., Scott Brancato, Mansen Wang, Kateri Spinelli, Maheer Gandhavadi, Neil Worrall, Eric J Lehr, Zachary M DeBoard, Torin Fitton, Alison Leiataua, Jonathan P Piccini, and Tyler J Gluckman

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Impact of a Laboratory-Developed Phenotypic Rapid Susceptibility Test Directly From Positive Blood Cultures on Time to Narrowest Effective Therapy in Patients With Gram-Negative Bacteremia: A Prospective Randomized Trial., Alyssa B Christensen, Brent Footer, Tobias Pusch, Kim Heath, Maha Iqbal, Lian Wang, Gregory Tallman, Cameron J Cover, Jennifer Marfori, Brian A Kendall, Nicholas L Stucky, Meagan Greckel, Ivor Thomas, Katelynn Tran, Salena Yip, and Margret Oethinger

Case: Stent Thrombosis – Attacked on All Fronts, CH Davies

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Transcatheter Aortic Valve Replacement for Severe Aortic Regurgitation in Patients With a Left Ventricular Assist Device., Ashwat S Dhillon, Brandon Jones, Robert W. Hodson, and Ethan C Korngold

Accelerating Cardiovascular Outcomes/Health Services Research Within Community-Based Health Systems-Lessons Learned and Steps Moving Forward, Tyler J Gluckman

Accelerating Cardiovascular Outcomes/Health Services Research Within Community-Based Health Systems-Lessons Learned and Steps Moving Forward, Tyler J Gluckman

Accelerating Cardiovascular Outcomes/Health Services Research Within Community-Based Health Systems-Lessons Learned and Steps Moving Forward, Tyler J Gluckman

Cardiovascular Sequelae of COVID-19, Tyler J Gluckman

Cardiovascular Sequelae of COVID-19 (Long-COVID and Post-Acute Sequelae of SARS-CoV-2 Infection) CV Sequelae of COVID-19 in Adults: Myocarditis and Other Mycoardial Involvement, PASC, Tyler J Gluckman

Cost of Prevention—How Much is Too much?, Tyler J Gluckman

Do Registries Help Us or Cost Us, Tyler J Gluckman

Incorporating the 2021 AHA/ACC Chest Pain Guidelines Into My Clinical Practice, Tyler J Gluckman

Optimizing LDL-C: Individualizing Treatment Using Statins and Nonstatin Therapy, Tyler J Gluckman

Prevention and Treatment of COVID-19: A Review of the Current Data, Tyler J Gluckman

Treadmill, Nuclear Myocardial Perfusion Imaging (MPI), and Cardiac PET, Tyler J Gluckman

ACC Expert Consensus Decision Pathway of Bleeding Management in Patients on Oral Anticoagulant and Cost Implications, Tyler J Gluckman and See full list of authors in comments

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Polyunsaturated fatty acids, omega-3 fatty acids, and eicosapentaenoic acid- mechanisms of action, Tyler J Gluckman and See full list of authors in comments

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Leveraging Healthcare System Data to Identify High-Risk Dyslipidemia Patients., Nayrana Griffith, Grace Bigham, Aparna Sajja, and Ty J Gluckman

Creation of an RN data coordinator role in a new heart transplant program results in improved data integrity and timeliness and promotes program improvement through tracking of quality and performance metrics., M Hite, S Verburg, Jill M Gelow, and P Higby

Population Health: Turning In-Basket Into ROI, X Huang and L Jones Larson

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Potential Impact of 2017 American College of Cardiology/American Heart Association Hypertension Guideline on Contemporary Practice: A Cross-Sectional Analysis From NCDR PINNACLE Registry., Aliza Hussain, Salim S Virani, Luke Zheng, Tyler J Gluckman, William B Borden, Frederick A Masoudi, and Thomas M Maddox

Assessing Barriers to Consistent Adult Congenital Heart Disease Care: When in Doubt, Ask the Patient, R Jin

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Comparison of 26-mm Evolut and 23-mm Sapien 3 Valves in TAVR for Small Aortic Annulus., Ruyun Jin, Emily J Cox, Branden Reynolds, Brydan Curtis, Robert W. Hodson, Michael Reed, Sameer Gafoor, Gary Grunkemeier, Matthew Forrester, and Michael Ring

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The CUSUM Slope Equals Observed Minus Expected Mortality and Can Be Visualized by a "Slope-Meter"., Ruyun Jin, Mansen Wang, Lian Wang, and Gary Grunkemeier

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PCM1-JAK2 Fusion Tyrosine Kinase Gene-Related Neoplasia: A Systematic Review of the Clinical Literature., Henry G Kaplan, Ruyun Jin, Carlo Bifulco, James M Scanlan, and David R Corwin

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Criteria for Defining Stages of Cardiogenic Shock Severity., Navin K Kapur, Manreet Kanwar, Shashank S Sinha, Katherine L Thayer, A Reshad Garan, Jaime Hernandez-Montfort, Yijing Zhang, Borui Li, Paulina Baca, Fatou Dieng, Neil M Harwani, Jacob Abraham, Gavin Hickey, Sandeep Nathan, Detlef Wencker, Shelley Hall, Andrew Schwartzman, Wissam Khalife, Song Li, Claudius Mahr, Ju H Kim, Esther Vorovich, Evan H Whitehead, Vanessa Blumer, and Daniel Burkhoff

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Intermittent Occlusion of the Superior Vena Cava to Improve Hemodynamics in Patients With Acutely Decompensated Heart Failure: The VENUS-HF Early Feasibility Study., Navin K Kapur, Michael S Kiernan, Irakli Gorgoshvili, Rayan Yousefzai, Esther E Vorovich, Ryan J Tedford, Andrew J Sauer, Jacob Abraham, Charles D Resor, Carey D Kimmelstiel, Keith H Benzuly, Daniel H Steinberg, Julie Messer, Daniel Burkhoff, and Richard H Karas

Single Acute Mechanical Circulatory Support Device Use is Associated with Reduced Mortality Compared to Multi-Agent Drug Therapy Alone for Cardiogenic Shock: An Analysis of the Cardiogenic Shock Working Group Registry, NK Kapur, B Li, Y Zhang, K Thayer, A Garan, J Hernandez-Montfort, M Kanwar, SS Sinha, C Mahr, and Jacob Abraham

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Clinical Factors and Outcomes When Real-World Heart Teams Overruled STS Risk Scores in TAVR Cases., Jackson M King, Morgan T Black, Ruyun Jin, Gary L Grunkemeier, Branden Reynolds, Brydan Curtis, Robert W. Hodson, Erika A Strehl, Sameer Gafoor, Matthew Forrester, Emily J Cox, and Michael Ring

The Multidisciplinary Management of NET Disease: Carcinoid Heart Disease, M E. Layoun

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Evaluation of inter-observer variability regarding aortic and mitral valve findings on transesophageal echocardiograms ordered for suspected endocarditis., Kristina B Moon, Matthew C Tattersall, Maame Adoe, Fauzia Osman, and Peter S Rahko

The Effect of Center Transplant Rate and the Use of Temporary Mechanical Circulatory Support on Heart Transplant Outcomes, Vidang P. Nguyen, Jacob Abraham, Sophia Airhart, Jill M Gelow, J Kay, and Kevin Koomalsingh

Increased Drug Intoxications Seen in Heart Transplant Donors During COVID-19 Pandemic, Vidang P. Nguyen, Jacob Abraham, Jill M Gelow, Kevin Koomalsingh, and Daniel S. Oseran

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ASO Visual Abstract: Impact of Locoregional Treatment on Survival in Young Patients with Early-Stage Breast Cancer Undergoing Upfront Surgery., Javier I Orozco, Jennifer Keller, Shu-Ching Chang, Crystal E Fancher, and Janie Grumley

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Impact of Locoregional Treatment on Survival in Young Patients with Early-Stage Breast Cancer undergoing Upfront Surgery., Javier I Orozco, Jennifer Keller, Shu-Ching Chang, Crystal E Fancher, and Janie Grumley

Case Studies: Digital Ischemia, Alejandro Perez

Disorders that mimic PAD, Alejandro Perez

Medical Management of PAD, Alejandro Perez

Medical Management of Venous disease, Alejandro Perez

Monoplace Chamber Operations Walkthrough, Alejandro Perez

Screening and Physical Evaluation of CLTI/PAD Patients, Alejandro Perez

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Fulminant Myocarditis Following SARS-CoV-2 Infection:, Saurabh Rajpal, Rami Kahwash, Matthew S Tong, Kelly Paschke, Anjali A Satoskar, Beth Foreman, Larry A Allen, Nicole M Bhave, Tyler J Gluckman, and Valentin Fuster

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Fulminant Myocarditis Following SARS-CoV-2 Infection: JACC Patient Care Pathways., Saurabh Rajpal, Rami Kahwash, Matthew S Tong, Kelly Paschke, Anjali A Satoskar, Beth Foreman, Larry A Allen, Nicole M Bhave, Tyler J Gluckman, and Valentin Fuster

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Discordance Between Standard Equations for Determination of LDL Cholesterol in Patients With Atherosclerosis., Aparna Sajja, Hsin-Fang Li, Kateri Spinelli, Roger S Blumenthal, Salim S Virani, Seth S Martin, and Tyler J Gluckman

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Clinical Trial Participation and COVID-19: a Descriptive Analysis from the American Heart Association's Get With The Guidelines Registry., Kevin S Shah, Adriana E Reyes-Miranda, Steven M Bradley, Khadijah Breathett, Sandeep R Das, Tyler J Gluckman, Divya Gupta, Daniel T Leung, R Kannan Mutharasan, Pamela N Peterson, Emily S Spivak, and Rashmee U Shah

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Clinical Trial Participation and COVID-19: a Descriptive Analysis from the American Heart Association's Get With The Guidelines Registry., Kevin S Shah, Adriana E Reyes-Miranda, Steven M Bradley, Khadijah Breathett, Sandeep R Das, Tyler J Gluckman, Divya Gupta, Daniel T Leung, R Kannan Mutharasan, Pamela N Peterson, Emily S Spivak, and Rashmee U Shah

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Preoperative Risk Prediction for Pancreatectomy: A Comparative Analysis of Three Scoring Systems., Holly Spitzer, Ryan Yang, Phillip Kemp Bohan, Shu-Ching Chang, Gary Grunkemeier, Timothy Vreeland, and Daniel W Nelson

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The Impact of Remote Optimization of Guideline-Directed Medical Therapy in Patients with NYHA Stage II and III Heart Failure, Maurice N. Tran, Christine Doran, Trevor Laursen, Kellie Graybosch, and Jacob Abraham

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2022 ACC Expert Consensus Decision Pathway on Cardiovascular Sequelae of COVID-19 in Adults: Myocarditis and Other Myocardial Involvement, Post-Acute Sequelae of SARS-CoV-2 Infection, and Return to Play: A Report of the American College of Cardiology Solution Set Oversight Committee., Writing Committee, Tyler J Gluckman, Nicole M Bhave, Larry A Allen, Eugene H Chung, Erica S Spatz, Enrico Ammirati, Aaron L Baggish, Biykem Bozkurt, William K Cornwell, Kimberly G Harmon, Jonathan H Kim, Anuradha Lala, Benjamin D Levine, Matthew W Martinez, Oyere Onuma, Dermot Phelan, Valentina O Puntmann, Saurabh Rajpal, Pam R Taub, and Amanda K Verma

Submissions from 2021

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Mechanical Circulatory Support Devices in the Intensive Care Unit: Post-Implant Care and Management, Jacob Abraham (Ed) and Joseph E. Parrillo (Ed)

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Chapter: Blood compatibility/hemolysis, Jacob Abraham

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Heart Failure-Related Cardiogenic Shock: Pathophysiology, Evaluation and Management Considerations: Review of Heart Failure-Related Cardiogenic Shock., Jacob Abraham, Vanessa Blumer, Dan Burkhoff, Mohit Pahuja, Shashank S Sinha, Carolyn Rosner, Esther Vorovich, Gillian Grafton, Aaron Bagnola, Jaime A Hernandez-Montfort, and Navin K Kapur

Cardiogenic Shock Working Group Global Summit: Case Presentation, Jacob Abraham and Vidang P. Nguyen

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Axillary transvalvular microaxial pump as bridge to transcatheter aortic valve replacement in cardiogenic shock, Jacob Abraham, Lian Wang, V Kumar, Eric B Kirker, and Kateri Spinelli

Portopulmonary rhapsody: everything you need to know about portopulmonary hypertension, Sophia Airhart

Recognizing and treating HFpEF: the biggest pulmonary arterial hypertension imitator!, Sophia Airhart

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Assessing hemodynamic response to submaximal exercise in pulmonary arterial hypertension patients using an implantable hemodynamic monitor., Sophia Airhart, Nima Badie, Mark Doyle, Priscilla Correa-Jacque, Curt Daniels, and Raymond Benza

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Reply: Transcarotid trumps transapical/direct aortic access for transcatheter aortic valve replacement-It's a no brainer!, Keith B Allen, Adnan K Chhatriwalla, John Saxon, James Hermiller, David Heimansohn, Sina Moainie, Raymond G McKay, Mohiuddin Cheema, Brandon Jones, Robert W Hodson, Ethan Korngold, and Eric Kirker

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THE BLEEDING RISK TREATMENT PARADOX AT THE PHYSICIAN 1 AND HOSPITAL LEVEL: IMPLICATIONS FOR REDUCING BLEEDING IN PATIENTS UNDERGOING PCI., Amit P Amin, Nathan Frogge, Hemant Kulkarni, Gene Ridolfi, Gregory Ewald, Rachel Miller, Bruce Hall, Susan Rogers, Tyler J Gluckman, Jeptha Curtis, Frederick A Masoudi, and Sunil V Rao

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Transradial Access for High-Risk Percutaneous Coronary Intervention: Implications of the Risk-Treatment Paradox., Amit P Amin, Sunil V Rao, Arnold H Seto, Manoj Thangam, Richard G Bach, Samir Pancholy, Ian C Gilchrist, Prashant Kaul, Binita Shah, Mauricio G Cohen, Ty J Gluckman, Anna Bortnick, James T DeVries, Hemant Kulkarni, and Frederick A Masoudi

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Tips and tricks for invasive assessment of aortic stenosis, Tamara Atkinson, Jayant Bagai, and Crispin Davies

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Repeated cross-sectional analysis of hydroxychloroquine deimplementation in the AHA COVID-19 CVD Registry., Steven M Bradley, Sophia Emmons-Bell, R Kannan Mutharasan, Fatima Rodriguez, Divya Gupta, Gregory Roth, Ty J Gluckman, Rashmee U Shah, Tracy Y Wang, Rohan Khera, Pamela N Peterson, and Sandeep Das

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Temporal trends and predictors of surgical ablation for atrial fibrillation in a large western US healthcare system, Scott Brancato, Mansen Wang, Kateri Spinelli, Alison Leiataua, James Brevig, Zachary M DeBoard, Torin Fitton, Maheer Gandhavadi, Jonathan P. Piccini, Neil Worrall, and Tyler J Gluckman

Experience in a blood conservation initiative in cardiac surgery, James Brevig, Ruyun Jin, and Matthew Ducsik

Pulmonary Hypertension And Exercise Intolerance: A Novel Use Of Cardiomems To Measure Hemodynamic Changes In Exercise, Andrew Cheng, Rola Khedraki, Carmen Wheeler, Samantha Bagsic, Orvar Jonsson, Maya Guglin, Mosi Bennett, Jacob Abraham, Ashrith Guha, and Thomas Heywood

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Major disparities in COVID-19 test positivity for patients with non-English preferred language even after accounting for race and social factors in the United States in 2020., Hannah Cohen-Cline, Hsin-Fang Li, Monique Gill, Fatima Rodriguez, Tina Hernandez-Boussard, Harry Wolberg, Jacob Lippa, and Keri B Vartanian

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The Cardiovascular Quality Improvement and Care Innovation Consortium: Inception of a Multicenter Collaborative to Improve Cardiovascular Care., CV-QUIC Collaborators, Steven M Bradley, Srinath Adusumalli, Amit P Amin, William B Borden, Sandeep R Das, William E Downey, Joseph E Ebinger, Joy Gelbman, Tyler J Gluckman, Abhinav Goyal, Divya Gupta, Umesh N Khot, Andrew E Levy, R Kannan Mutharasan, Pam Rush, Craig E Strauss, Satya Shreenivas, and P Michael Ho

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Surge effects and survival to hospital discharge in critical care patients with COVID-19 during the early pandemic: a cohort study., Chris Dale, Rachael Starcher, Shu-Ching Chang, Ari Robicsek, Guilford Parsons, Jason D Goldman, Andre Vovan, David Hotchkin, and Tyler J Gluckman

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Echocardiographic Ischemic Memory Molecular Imaging for Point-of-Care Detection of Myocardial Ischemia., Brian P Davidson, James Hodovan, Michael Layoun, Harsh Golwala, Firas Zahr, and Jonathan R Lindner

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Echocardiographic Ischemic Memory Molecular Imaging for Point-of-Care Detection of Myocardial Ischemia., Brian P Davidson, James Hodovan, Michael Layoun, Harsh Golwala, Firas Zahr, and Jonathan R Lindner

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Remdesivir and Mortality in Patients with COVID-19., George A Diaz, Alyssa B Christensen, Tobias Pusch, Delaney Goulet, Shu-Ching Chang, Gary L Grunkemeier, Paul A McKelvey, Ari Robicsek, Tom French, Guilford T Parsons, Glenn Doherty, Charles Laurenson, Ryan Roper, Jennifer Hadlock, Cameron J Cover, Brent Footer, Philip Robinson, Mary Micikas, Jennifer E Marfori, Charlotte Cronenweth, Yogavedya Mukkamala, Jamie Mackiewicz, Ekra Rai, Martha Dickinson Matson, Jodie Davila, Justin Rueda, Reda Tipton, Heather Algren, Brittney C Ward, Stephen Malkoski, Tyler Gluckman, Gregory B Tallman, Henry Arguinchona, Terese C Hammond, Steven Standaert, Joshua Christensen, Jose F Echaiz, Robert Choi, Daniel McClung, Albert Pacifico, Martin Fee, Farjad Sarafian, William R Berrington, and Jason D Goldman

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Hypertrophic cardiomyopathy: diagnosis and therapeutic options., Ty J Gluckman

Cardiovascular care in unusual places—delivering value beyond bricks and mortar, Tyler J Gluckman

Cardiovascular involvement in COVID-19: The good, the bad, and the unknown, Tyler J Gluckman

Clinical care in a post-pandemic world: what we learned and where we go from here, Tyler J Gluckman

COVID-19’s impact on common cardiovascular quality metrics, Tyler J Gluckman

Evolving treatment approaches for hypertrophic cardiomyopathy, Tyler J Gluckman

How will selected 2021 ACC clinical trial findings change our practice?, Tyler J Gluckman

Optimal LDL-cholesterol: Individualizing treatment using statins and nonstatin therapy, Tyler J Gluckman

Peer-to-peer quality programs that actually work, Tyler J Gluckman

Quality of care, appropriate use criteria, the ACC-NCDR Registry and professional code of ethics, Tyler J Gluckman

Same day discharge- what opportunities exist and why should I be doing it?, Tyler J Gluckman

Same day discharge- what opportunities exist and why should I be doing it?, Tyler J Gluckman

What did we learn from COVID-19?, Tyler J Gluckman

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Evolving Treatment Approaches for Hypertrophic Cardiomyopathy: Essential Updates for Specialty Pharmacy, Tyler J Gluckman, Martin S. Maron, Ryan J. Atkinson, Donna M. Chiefari, Judith R. Sands, and Henry A. Solomon

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Clinical Outcomes Associated With Acute Mechanical Circulatory Support Utilization in Heart Failure Related Cardiogenic Shock., Jaime Hernandez-Montfort, Shashank S Sinha, Katherine L Thayer, Evan H Whitehead, Mohit Pahuja, Arthur Reshad Garan, Claudius Mahr, Jillian L Haywood, Neil M Harwani, August Schaeffer, Detlef Wencker, Manreet Kanwar, Esther Vorovich, Jacob Abraham, Daniel Burkhoff, and Navin K Kapur

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Right Ventricular Dysfunction Is Common and Identifies Patients at Risk of Dying in Cardiogenic Shock., Pankaj Jain, Katherine L Thayer, Jacob Abraham, Kay D Everett, Mohit Pahuja, Evan H Whitehead, Benjamin P Schwartz, Anuradha Lala, Shashank S Sinha, Manreet K Kanwar, A Reshad Garan, Jaime A Hernandez-Monfort, Claudius Mahr, Esther Vorovich, Detlef Wencker, James M McCabe, Tara Jones, Maithri Goud, Paulina Baca, Neil Harwani, Daniel Burkhoff, and Navin K Kapur

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Continuous Monitoring of Risk-Adjusted Outcomes: Excess Deaths vs. Lives Saved., Ruyun Jin, Gary L Grunkemeier, and Anthony P Furnary

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Comparable Outcomes for Transcarotid and Transfemoral Transcatheter Aortic Valve Replacement at a High Volume US Center., Brandon Jones, V Kumar, Shih-Ting Chiu, Ethan C Korngold, Robert W. Hodson, Kateri Spinelli, and Eric B Kirker

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Rapid, successful adoption of virtual outpatient cardiology care during the COVID-19 pandemic, Lesley Jones Larson, D Christensen, S Long, Lian Wang, Kateri Spinelli, and Xiaoyan Huang

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Impact of Age on Outcomes in Patients With Cardiogenic Shock., Manreet Kanwar, Katherine L Thayer, Arthur Reshad Garan, Jaime Hernandez-Montfort, Evan Whitehead, Claudius Mahr, Shashank S Sinha, Esther Vorovich, Neil M Harwani, Elric Zweck, Jacob Abraham, Daniel Burkhoff, and Navin K Kapur

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Impact of age on outcomes in patients with cardiogenic shock, M Kanwar, KL Thayer, A Garan, J Hernandez-Montfort, EH Whitehead, C Mahr, S Sinha, E Vorovich, NM Harwani, E Zweck, Jacob Abraham, and D Burkhoff

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The Benefits of Transcarotid Access for Transcatheter Aortic Valve Replacement: When will we stop being so surprised?, Eric B Kirker and Brandon Jones

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Hospital Procedure Volume Not Associated with 30-day Stroke Rate for Transcarotid or Transaxillary/Subclavian TAVR., Eric Kirker and Brandon Jones

Alternative access: Transcarotid, Ethan C Korngold

Cardiovascular risk assessment and disease management in patients with cancer, Michael Layoun

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Chapter: Cardiovascular complications, Michael Layoun and M Ferencik