Providence Center for Cardiovascular Analytics, Research + Data Science (CARDS) is dedicated to leveraging our data and research infrastructure to accelerate innovation and discovery in heart and vascular health for the betterment of patient care. To support Providence Heart Institute’s research and quality efforts, the CARDS center includes analytics, registries, biostatistics, publications, and clinical trials. CARDS investigates the treatments, technologies and processes that lead to the best patient outcomes in service to high-value cardiovascular care. CARDS conducts research ‘in the context of clinical practice’, asking and answering important questions that will shape patient care and influence how our health care delivery systems are organized. CARDS leverages Providence’s real-world health care experience to create new knowledge.

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Submissions from 2022

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Axillary transvalvular microaxial pump as extended bridge to transcatheter aortic valve replacement in cardiogenic shock with severe aortic stenosis., Jacob Abraham, Lian Wang, Vishesh Kumar, Eric B Kirker, and Kateri Spinelli

Controversial Debates in Pulmonary Hypertension. Invasive Hemodynamics are Essential for Risk Stratification in PAH (PRO), Sophia Airhart

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Temporal trends and predictors of surgical ablation for atrial fibrillation across a multistate healthcare system., Scott Brancato, Mansen Wang, Kateri Spinelli, Maheer Gandhavadi, Neil Worrall, Eric J Lehr, Zachary M DeBoard, Torin Fitton, Alison Leiataua, Jonathan P Piccini, and Tyler J Gluckman

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Transcatheter Aortic Valve Replacement for Severe Aortic Regurgitation in Patients With a Left Ventricular Assist Device., Ashwat S Dhillon, Brandon Jones, Robert W. Hodson, and Ethan C Korngold

Accelerating Cardiovascular Outcomes/Health Services Research Within Community-Based Health Systems-Lessons Learned and Steps Moving Forward, Tyler J Gluckman

Do Registries Help Us or Cost Us, Tyler J Gluckman

Incorporating the 2021 AHA/ACC Chest Pain Guidelines Into My Clinical Practice, Tyler J Gluckman

Optimizing LDL-C: Individualizing Treatment Using Statins and Nonstatin Therapy, Tyler J Gluckman

Prevention and Treatment of COVID-19: A Review of the Current Data, Tyler J Gluckman

ACC Expert Consensus Decision Pathway of Bleeding Management in Patients on Oral Anticoagulant and Cost Implications, Tyler J Gluckman and See full list of authors in comments

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Polyunsaturated fatty acids, omega-3 fatty acids, and eicosapentaenoic acid- mechanisms of action, Tyler J Gluckman and See full list of authors in comments

Creation of an RN data coordinator role in a new heart transplant program results in improved data integrity and timeliness and promotes program improvement through tracking of quality and performance metrics., M Hite, S Verburg, Jill M Gelow, and P Higby

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Potential Impact of 2017 American College of Cardiology/American Heart Association Hypertension Guideline on Contemporary Practice: A Cross-Sectional Analysis From NCDR PINNACLE Registry., Aliza Hussain, Salim S Virani, Luke Zheng, Tyler J Gluckman, William B Borden, Frederick A Masoudi, and Thomas M Maddox

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The CUSUM Slope Equals Observed Minus Expected Mortality and Can Be Visualized by a "Slope-Meter"., Ruyun Jin, Mansen Wang, Lian Wang, and Gary Grunkemeier

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PCM1-JAK2 Fusion Tyrosine Kinase Gene-Related Neoplasia: A Systematic Review of the Clinical Literature., Henry G Kaplan, Ruyun Jin, Carlo Bifulco, James M Scanlan, and David R Corwin

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Intermittent Occlusion of the Superior Vena Cava to Improve Hemodynamics in Patients With Acutely Decompensated Heart Failure: The VENUS-HF Early Feasibility Study., Navin K Kapur, Michael S Kiernan, Irakli Gorgoshvili, Rayan Yousefzai, Esther E Vorovich, Ryan J Tedford, Andrew J Sauer, Jacob Abraham, Charles D Resor, Carey D Kimmelstiel, Keith H Benzuly, Daniel H Steinberg, Julie Messer, Daniel Burkhoff, and Richard H Karas

Single Acute Mechanical Circulatory Support Device Use is Associated with Reduced Mortality Compared to Multi-Agent Drug Therapy Alone for Cardiogenic Shock: An Analysis of the Cardiogenic Shock Working Group Registry, NK Kapur, B Li, Y Zhang, K Thayer, A Garan, J Hernandez-Montfort, M Kanwar, SS Sinha, C Mahr, and Jacob Abraham

The Effect of Center Transplant Rate and the Use of Temporary Mechanical Circulatory Support on Heart Transplant Outcomes, Vidang P. Nguyen, Jacob Abraham, Sophia Airhart, Jill M Gelow, J Kay, and Kevin Koomalsingh

Increased Drug Intoxications Seen in Heart Transplant Donors During COVID-19 Pandemic, Vidang P. Nguyen, Jacob Abraham, Jill M Gelow, Kevin Koomalsingh, and Daniel S. Oseran

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Discordance Between Standard Equations for Determination of LDL Cholesterol in Patients With Atherosclerosis., Aparna Sajja, Hsin-Fang Li, Kateri Spinelli, Roger S Blumenthal, Salim S Virani, Seth S Martin, and Tyler J Gluckman

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Clinical Trial Participation and COVID-19: a Descriptive Analysis from the American Heart Association's Get With The Guidelines Registry., Kevin S Shah, Adriana E Reyes-Miranda, Steven M Bradley, Khadijah Breathett, Sandeep R Das, Tyler J Gluckman, Divya Gupta, Daniel T Leung, R Kannan Mutharasan, Pamela N Peterson, Emily S Spivak, and Rashmee U Shah

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Clinical Trial Participation and COVID-19: a Descriptive Analysis from the American Heart Association's Get With The Guidelines Registry., Kevin S Shah, Adriana E Reyes-Miranda, Steven M Bradley, Khadijah Breathett, Sandeep R Das, Tyler J Gluckman, Divya Gupta, Daniel T Leung, R Kannan Mutharasan, Pamela N Peterson, Emily S Spivak, and Rashmee U Shah

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The Impact of Remote Optimization of Guideline-Directed Medical Therapy in Patients with NYHA Stage II and III Heart Failure, Maurice N. Tran, Christine Doran, Trevor Laursen, Kellie Graybosch, and Jacob Abraham

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2022 ACC Expert Consensus Decision Pathway on Cardiovascular Sequelae of COVID-19 in Adults: Myocarditis and Other Myocardial Involvement, Post-Acute Sequelae of SARS-CoV-2 Infection, and Return to Play: A Report of the American College of Cardiology Solution Set Oversight Committee., Writing Committee, Tyler J Gluckman, Nicole M Bhave, Larry A Allen, Eugene H Chung, Erica S Spatz, Enrico Ammirati, Aaron L Baggish, Biykem Bozkurt, William K Cornwell, Kimberly G Harmon, Jonathan H Kim, Anuradha Lala, Benjamin D Levine, Matthew W Martinez, Oyere Onuma, Dermot Phelan, Valentina O Puntmann, Saurabh Rajpal, Pam R Taub, and Amanda K Verma

Submissions from 2021

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Mechanical Circulatory Support Devices in the Intensive Care Unit: Post-Implant Care and Management, Jacob Abraham (Ed) and Joseph E. Parrillo (Ed)

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Chapter: Blood compatibility/hemolysis, Jacob Abraham

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Heart Failure-Related Cardiogenic Shock: Pathophysiology, Evaluation and Management Considerations: Review of Heart Failure-Related Cardiogenic Shock., Jacob Abraham, Vanessa Blumer, Dan Burkhoff, Mohit Pahuja, Shashank S Sinha, Carolyn Rosner, Esther Vorovich, Gillian Grafton, Aaron Bagnola, Jaime A Hernandez-Montfort, and Navin K Kapur

Cardiogenic Shock Working Group Global Summit: Case Presentation, Jacob Abraham and Vidang P. Nguyen

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Axillary transvalvular microaxial pump as bridge to transcatheter aortic valve replacement in cardiogenic shock, Jacob Abraham, Lian Wang, V Kumar, Eric B Kirker, and Kateri Spinelli

Portopulmonary rhapsody: everything you need to know about portopulmonary hypertension, Sophia Airhart

Recognizing and treating HFpEF: the biggest pulmonary arterial hypertension imitator!, Sophia Airhart

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Assessing hemodynamic response to submaximal exercise in pulmonary arterial hypertension patients using an implantable hemodynamic monitor., Sophia Airhart, Nima Badie, Mark Doyle, Priscilla Correa-Jacque, Curt Daniels, and Raymond Benza

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Reply: Transcarotid trumps transapical/direct aortic access for transcatheter aortic valve replacement-It's a no brainer!, Keith B Allen, Adnan K Chhatriwalla, John Saxon, James Hermiller, David Heimansohn, Sina Moainie, Raymond G McKay, Mohiuddin Cheema, Brandon Jones, Robert W Hodson, Ethan Korngold, and Eric Kirker

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THE BLEEDING RISK TREATMENT PARADOX AT THE PHYSICIAN 1 AND HOSPITAL LEVEL: IMPLICATIONS FOR REDUCING BLEEDING IN PATIENTS UNDERGOING PCI., Amit P Amin, Nathan Frogge, Hemant Kulkarni, Gene Ridolfi, Gregory Ewald, Rachel Miller, Bruce Hall, Susan Rogers, Tyler J Gluckman, Jeptha Curtis, Frederick A Masoudi, and Sunil V Rao

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Transradial Access for High-Risk Percutaneous Coronary Intervention: Implications of the Risk-Treatment Paradox., Amit P Amin, Sunil V Rao, Arnold H Seto, Manoj Thangam, Richard G Bach, Samir Pancholy, Ian C Gilchrist, Prashant Kaul, Binita Shah, Mauricio G Cohen, Ty J Gluckman, Anna Bortnick, James T DeVries, Hemant Kulkarni, and Frederick A Masoudi

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Tips and tricks for invasive assessment of aortic stenosis, Tamara Atkinson, Jayant Bagai, and Crispin Davies

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Repeated cross-sectional analysis of hydroxychloroquine deimplementation in the AHA COVID-19 CVD Registry., Steven M Bradley, Sophia Emmons-Bell, R Kannan Mutharasan, Fatima Rodriguez, Divya Gupta, Gregory Roth, Ty J Gluckman, Rashmee U Shah, Tracy Y Wang, Rohan Khera, Pamela N Peterson, and Sandeep Das

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Temporal trends and predictors of surgical ablation for atrial fibrillation in a large western US healthcare system, Scott Brancato, Mansen Wang, Kateri Spinelli, Alison Leiataua, James Brevig, Zachary M DeBoard, Torin Fitton, Maheer Gandhavadi, Jonathan P. Piccini, Neil Worrall, and Tyler J Gluckman

Experience in a blood conservation initiative in cardiac surgery, James Brevig, Ruyun Jin, and Matthew Ducsik

Pulmonary Hypertension And Exercise Intolerance: A Novel Use Of Cardiomems To Measure Hemodynamic Changes In Exercise, Andrew Cheng, Rola Khedraki, Carmen Wheeler, Samantha Bagsic, Orvar Jonsson, Maya Guglin, Mosi Bennett, Jacob Abraham, Ashrith Guha, and Thomas Heywood

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Major disparities in COVID-19 test positivity for patients with non-English preferred language even after accounting for race and social factors in the United States in 2020., Hannah Cohen-Cline, Hsin-Fang Li, Monique Gill, Fatima Rodriguez, Tina Hernandez-Boussard, Harry Wolberg, Jacob Lippa, and Keri B Vartanian

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The Cardiovascular Quality Improvement and Care Innovation Consortium: Inception of a Multicenter Collaborative to Improve Cardiovascular Care., CV-QUIC Collaborators, Steven M Bradley, Srinath Adusumalli, Amit P Amin, William B Borden, Sandeep R Das, William E Downey, Joseph E Ebinger, Joy Gelbman, Tyler J Gluckman, Abhinav Goyal, Divya Gupta, Umesh N Khot, Andrew E Levy, R Kannan Mutharasan, Pam Rush, Craig E Strauss, Satya Shreenivas, and P Michael Ho

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Surge effects and survival to hospital discharge in critical care patients with COVID-19 during the early pandemic: a cohort study., Chris Dale, Rachael Starcher, Shu-Ching Chang, Ari Robicsek, Guilford Parsons, Jason D Goldman, Andre Vovan, David Hotchkin, and Tyler J Gluckman

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Echocardiographic Ischemic Memory Molecular Imaging for Point-of-Care Detection of Myocardial Ischemia., Brian P Davidson, James Hodovan, Michael Layoun, Harsh Golwala, Firas Zahr, and Jonathan R Lindner

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Echocardiographic Ischemic Memory Molecular Imaging for Point-of-Care Detection of Myocardial Ischemia., Brian P Davidson, James Hodovan, Michael Layoun, Harsh Golwala, Firas Zahr, and Jonathan R Lindner

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Remdesivir and Mortality in Patients with COVID-19., George A Diaz, Alyssa B Christensen, Tobias Pusch, Delaney Goulet, Shu-Ching Chang, Gary L Grunkemeier, Paul A McKelvey, Ari Robicsek, Tom French, Guilford T Parsons, Glenn Doherty, Charles Laurenson, Ryan Roper, Jennifer Hadlock, Cameron J Cover, Brent Footer, Philip Robinson, Mary Micikas, Jennifer E Marfori, Charlotte Cronenweth, Yogavedya Mukkamala, Jamie Mackiewicz, Ekra Rai, Martha Dickinson Matson, Jodie Davila, Justin Rueda, Reda Tipton, Heather Algren, Brittney C Ward, Stephen Malkoski, Tyler Gluckman, Gregory B Tallman, Henry Arguinchona, Terese C Hammond, Steven Standaert, Joshua Christensen, Jose F Echaiz, Robert Choi, Daniel McClung, Albert Pacifico, Martin Fee, Farjad Sarafian, William R Berrington, and Jason D Goldman

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Hypertrophic cardiomyopathy: diagnosis and therapeutic options., Ty J Gluckman

Cardiovascular care in unusual places—delivering value beyond bricks and mortar, Tyler J Gluckman

Cardiovascular involvement in COVID-19: The good, the bad, and the unknown, Tyler J Gluckman

Clinical care in a post-pandemic world: what we learned and where we go from here, Tyler J Gluckman

COVID-19’s impact on common cardiovascular quality metrics, Tyler J Gluckman

Evolving treatment approaches for hypertrophic cardiomyopathy, Tyler J Gluckman

How will selected 2021 ACC clinical trial findings change our practice?, Tyler J Gluckman

Optimal LDL-cholesterol: Individualizing treatment using statins and nonstatin therapy, Tyler J Gluckman

Peer-to-peer quality programs that actually work, Tyler J Gluckman

Quality of care, appropriate use criteria, the ACC-NCDR Registry and professional code of ethics, Tyler J Gluckman

Same day discharge- what opportunities exist and why should I be doing it?, Tyler J Gluckman

Same day discharge- what opportunities exist and why should I be doing it?, Tyler J Gluckman

What did we learn from COVID-19?, Tyler J Gluckman

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Evolving Treatment Approaches for Hypertrophic Cardiomyopathy: Essential Updates for Specialty Pharmacy, Tyler J Gluckman, Martin S. Maron, Ryan J. Atkinson, Donna M. Chiefari, Judith R. Sands, and Henry A. Solomon

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Clinical Outcomes Associated With Acute Mechanical Circulatory Support Utilization in Heart Failure Related Cardiogenic Shock., Jaime Hernandez-Montfort, Shashank S Sinha, Katherine L Thayer, Evan H Whitehead, Mohit Pahuja, Arthur Reshad Garan, Claudius Mahr, Jillian L Haywood, Neil M Harwani, August Schaeffer, Detlef Wencker, Manreet Kanwar, Esther Vorovich, Jacob Abraham, Daniel Burkhoff, and Navin K Kapur

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Right Ventricular Dysfunction Is Common and Identifies Patients at Risk of Dying in Cardiogenic Shock., Pankaj Jain, Katherine L Thayer, Jacob Abraham, Kay D Everett, Mohit Pahuja, Evan H Whitehead, Benjamin P Schwartz, Anuradha Lala, Shashank S Sinha, Manreet K Kanwar, A Reshad Garan, Jaime A Hernandez-Monfort, Claudius Mahr, Esther Vorovich, Detlef Wencker, James M McCabe, Tara Jones, Maithri Goud, Paulina Baca, Neil Harwani, Daniel Burkhoff, and Navin K Kapur

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Continuous Monitoring of Risk-Adjusted Outcomes: Excess Deaths vs. Lives Saved., Ruyun Jin, Gary L Grunkemeier, and Anthony P Furnary

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Comparable Outcomes for Transcarotid and Transfemoral Transcatheter Aortic Valve Replacement at a High Volume US Center., Brandon Jones, V Kumar, Shih-Ting Chiu, Ethan C Korngold, Robert W. Hodson, Kateri Spinelli, and Eric B Kirker

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Rapid, successful adoption of virtual outpatient cardiology care during the COVID-19 pandemic, Lesley Jones Larson, D Christensen, S Long, Lian Wang, Kateri Spinelli, and Xiaoyan Huang

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Impact of Age on Outcomes in Patients With Cardiogenic Shock., Manreet Kanwar, Katherine L Thayer, Arthur Reshad Garan, Jaime Hernandez-Montfort, Evan Whitehead, Claudius Mahr, Shashank S Sinha, Esther Vorovich, Neil M Harwani, Elric Zweck, Jacob Abraham, Daniel Burkhoff, and Navin K Kapur

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Impact of age on outcomes in patients with cardiogenic shock, M Kanwar, KL Thayer, A Garan, J Hernandez-Montfort, EH Whitehead, C Mahr, S Sinha, E Vorovich, NM Harwani, E Zweck, Jacob Abraham, and D Burkhoff

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The Benefits of Transcarotid Access for Transcatheter Aortic Valve Replacement: When will we stop being so surprised?, Eric B Kirker and Brandon Jones

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Hospital Procedure Volume Not Associated with 30-day Stroke Rate for Transcarotid or Transaxillary/Subclavian TAVR., Eric Kirker and Brandon Jones

Alternative access: Transcarotid, Ethan C Korngold

Cardiovascular risk assessment and disease management in patients with cancer, Michael Layoun

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Chapter: Cardiovascular complications, Michael Layoun and M Ferencik

Dry Field Closure of Large-Bore Access With Iliac Artery Angioplasty Through the Ipsilateral Sheath: The Single-Access Dry-Closure Technique., Hady Lichaa, Jason R Wollmuth, and Rajiv Tayal

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Plasma Lipidomic Patterns in Patients with Symptomatic Coronary Microvascular Dysfunction., Jonathan R Lindner, Brian P Davidson, Zifeng Song, Claudia S Maier, Jessica Minnier, Jan Frederick Stevens, Maros Ferencik, Sahar Taqui, J Todd Belcik, Federico Moccetti, Michael Layoun, Paul Spellman, Mitchell S Turker, Hagai Tavori, Sergio Fazio, Jacob Raber, and Gerd Bobe

Impella 5.5 as a bridge to repair in a post-infarct ventricular septal defect, Vidang P. Nguyen, Ethan C Korngold, and Jacob Abraham

Hyperbaric oxygen therapy: monoplace chamber, A Perez

Cardiac disease and vascular imaging, Alejandro Perez

Coding changes for wound care clinician-2021 updates, Alejandro Perez

Demographics and cost of venous leg ulcers, Alejandro Perez

Efforts and progress on key vascular quality measures, Alejandro Perez

Hyperbaric oxygen therapy: treatment indications, Alejandro Perez

Peripheral arterial disease: diagnosis and medical management, Alejandro Perez

Peripheral artery disease: basic principles for the wound care clinician, Alejandro Perez

Scanning below the knee arteries- how to determine stenosis when there no validated criteria?, Alejandro Perez

Venous purple toe syndrome: a variant of acrocyanosis, Alejandro Perez

Wound care local coverage determination, Alejandro Perez

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A standardized optical coherence tomography workflow improves procedural efficiency and safety during percutaneous coronary intervention: insights from the LightLab Initiative, Judah Rauch, Michael Johnson, Aziz Maksoud, Daniel Spoon, Frank Zidar, Ethan C Korngold, Jana Buccola, Hector Garcia Cabrera, Richard Rapoza, Nick West, and Eric Osborn

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Successful pivot of a community exercise program to virtual during the COVID-19 pandemic, LeTracia Rose and James G Beckerman

Heart to heart: cardiology and nephrology discuss heart failure management, A Ross and C Kassakian

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Excess Mortality Among Patients Hospitalized During the COVID-19 Pandemic., Amber K Sabbatini, Ari Robicsek, Shih-Ting Chiu, and Ty J Gluckman

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A simplified approach to identification of risk status in patients with atherosclerotic cardiovascular disease, Aparna Sajja, Hsin-Fang Li, Kateri Spinelli, Amir Ali, Salim S. Virani, Seth S. Martin, and Tyler J Gluckman

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Concordance of LDL-cholesterol levels between the Friedewald, Martin/Hopkins, and Sampson equations in patients with atherosclerotic cardiovascular disease, Aparna Sajja, Hsin-Fang Li, Kateri Spinelli, Salim S. Virani, Seth S. Martin, and Tyler J Gluckman

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CardioMEMS guided treatment of chronic HF patients supported with a HeartMate LVAD: INTELLECT 2-HF study, V Thohan, Jacob Abraham, A Burdof, DJ Farrar, N Dirckx, AT Baker, and SG Drakos

Strategic interventional approach to femoropopliteal occlusive disease, Brant Ullery

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Cryoballoon Ablation as Initial Therapy for Atrial Fibrillation., Oussama M Wazni, Gopi Dandamudi, Nitesh Sood, Robert Hoyt, Jaret Tyler, Sarfraz Durrani, Mark Niebauer, Kevin Makati, Blair Halperin, Andre Gauri, Gustavo Morales, Mingyuan Shao, Jeffrey Cerkvenik, Rachelle E Kaplon, Steven E Nissen, and STOP AF First Trial Investigators

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A Comparison of statistical methods for hospital performance assessment, Xiaoting Wu, Min Zhang, Ruyun Jin, Gary Grunkemeier, Charles Maynard, Ravi S. Hira, Todd Mackenzie, Morley Herbert, Chang He, Sari D. Holmes, Michael P. Thompson, and Donald S. Likosky

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Cardiovascular Procedural Deferral and Outcomes over COVID-19 Pandemic Phases: A Multi-Center Study., Celina M Yong, Kateri J Spinelli, Shih Ting Chiu, Brandon Jones, Brian Penny, Santosh Gummidipundi, Shire Beach, Alex Perino, Mintu Turakhia, Paul Heidenreich, and Ty J Gluckman

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Phenotyping Cardiogenic Shock., Elric Zweck, Katherine L Thayer, Ole K L Helgestad, Manreet Kanwar, Mohyee Ayouty, A Reshad Garan, Jaime Hernandez-Montfort, Claudius Mahr, Detlef Wencker, Shashank S Sinha, Esther Vorovich, Jacob Abraham, William O'Neill, Song Li, Gavin W Hickey, Jakob Josiassen, Christian Hassager, Lisette O Jensen, Lene Holmvang, Henrik Schmidt, Hanne B Ravn, Jacob E Møller, Daniel Burkhoff, and Navin K Kapur

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Compatibility of novel cardiogenic shock phenotypes from the Cardiogenic Shock Working Group (CSWG) with the SCAI staging system, E Zweck, KL Thayer, OK Helgestad, M Kanwar, M Ayouty, A Garan, J Hernandez-Montfort, C Mahr, D Wencker, S Sinha, E Vorovich, Jacob Abraham, W O'Neill, S Li, GW Hickey, J Jossiasen, C Hassager, LO Jensen, L Holmvang, H Schmidt, HB Ravn, JE Moeller, D Burkhoff, and NK Kapur

Submissions from 2020

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Management of the Patient with Heart Failure and an Implantable Pulmonary Artery Hemodynamic Sensor, Jacob Abraham, Patrick J. McCann, Maya E. Guglin, Arvind Bhimaraj, Terrie-Ann S. Benjamin, Monique R. Robinson, Orvar T. Jonsson, Scott C. Feitell, Kunjan A. Bhatt, Mosi K. Bennett, JT Heywood, and Hemodynamic Frontiers in Heart Failure (HF2) Investigators