The Cancer Institute is a leader in cutting-edge treatments. Using a truly multidisciplinary approach, patients have access to advanced diagnostics, minimally invasive surgical interventions, and personalized genomic and immune-oncologic treatment options. Our team of cancer specialists – many of whom completed fellowships and specialty training at prestigious academic centers – offers comprehensive services for individuals with a cancer diagnosis.

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Submissions from 2020

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Molecular genomic profiling of adrenocortical cancers in clinical practice., Sourat Darabi, David R Braxton, Burton L Eisenberg, and Michael J Demeure

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Predictive Biomarkers for Immunotherapy Response Beyond PD-1/PD-L1., Sourat Darabi, David R Braxton, Burton L Eisenberg, and Michael J Demeure

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Impact of geography and travel distance on outcomes in epithelial ovarian cancer: a national cancer database analysis., Ava Daruvala, F Lee Lucas, Jesse Sammon, Christopher Darus, and Leslie Bradford

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368 REVEAL: Phase 1 dose-escalation study of NKTR-262, a novel TLR7/8 agonist, plus bempegaldesleukin: local innate immune activation and systemic adaptive immune expansion for treating solid tumors, Adi Daub, Brendan Curti, Mehmet Bilen, Andrew Brohl, Evidio Domingo-Musibay, Erkut Borazanci, Christine Fanton, Cat Haglund, Mona Vimal, Mann Muhsin, Mario Marcondes, Anh Nguyen, Mary Tagliaferri, Wei Lin, Jonathan Zalevsky, and Sandra D'Angelo

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420 Progression-free survival and biomarker correlates of response with BEMPEG plus NIVO in previously untreated patients with metastatic melanoma: results from the PIVOT-02 study, Adi Daub, Scott Tykodi, Gregory Daniels, Michele Maio, Brendan Curti, Karl Lewis, Sekwon Jang, Ewa Kalinka, Igor Puzanov, Alexander Spira, Daneil Cho, Shanhong Guan, Erika Puente, Ute Hoch, Sue Currie, Tuan Nguyen, Wei Lin, Mary Tagliaferri, Jonathan Zalevsky, Mario Sznol, and Michael Hurwitz

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Olaparib for Metastatic Castration-Resistant Prostate Cancer., Johann de Bono, Joaquin Mateo, Karim Fizazi, Fred Saad, Neal Shore, Shahneen Sandhu, Kim N Chi, Oliver Sartor, Neeraj Agarwal, David Olmos, Antoine Thiery-Vuillemin, Przemyslaw Twardowski, Niven Mehra, Carsten Goessl, Jinyu Kang, Joseph Burgents, Wenting Wu, Alexander Kohlmann, Carrie A Adelman, and Maha Hussain

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Characterizing diversity in the tumor-immune microenvironment of distinct subclasses of gastroesophageal adenocarcinomas., S Derks, L K de Klerk, X Xu, T Fleitas, K X Liu, Y Liu, F Dietlein, C Margolis, A M Chiaravalli, A C Da Silva, S Ogino, F G Akarca, G J Freeman, S J Rodig, J L Hornick, E van Allen, B Li, S X Liu, V Thorsson, and A J Bass

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368 REVEAL: Phase 1 dose-escalation study of NKTR-262, a novel TLR7/8 agonist, plus bempegaldesleukin: local innate immune activation and systemic adaptive immune expansion for treating solid tumors, Abi Diab, Brendan Curti, Mehmet Bilen, Andrew Brohl, Evidio Domingo-Musibay, Erkut Borazanci, Christine Falon, Cat Haglund, Mona Vimal, Mann Muhsin, Mario Marcondes, Anh Nguyen, Mary Tagliaferri, Wei Lin, Jonathan Zalevsky, and Sandra D'Angelo

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Bempegaldesleukin (NKTR-214) plus Nivolumab in Patients with Advanced Solid Tumors: Phase I Dose-Escalation Study of Safety, Efficacy, and Immune Activation (PIVOT-02)., Adi Diab, Nizar M Tannir, Salah-Eddine Bentebibel, Patrick Hwu, Vassiliki Papadimitrakopoulou, Cara Haymaker, Harriet M Kluger, Scott N Gettinger, Mario Sznol, Scott S Tykodi, Brendan Curti, Mary A Tagliaferri, Jonathan Zalevsky, Alison L Hannah, Ute Hoch, Sandra Aung, Christie Fanton, Ahsan Rizwan, Ernesto Iacucci, Yijie Liao, Chantale Bernatchez, Michael E Hurwitz, and Daniel C Cho

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420 Progression-free survival and biomarker correlates of response with BEMPEG plus NIVO in previously untreated patients with metastatic melanoma: results from the PIVOT-02 study, Adi Diab, Scott Tykodi, Gregory Daniels, Michele Maio, Brendan Curti, Karl Lewis, Sekwon Jang, Ewa Kalinka, Igor Puzanov, Alexander Spira, Daniel Cho, Shanhong Guan, Erika Puente, Ute Hoch, Sue Currie, Tuan Nguyen, Wei Lin, Mary Tagliaferri, Jonathan Zalevsky, Mario Sznol, and Michael Hurwitz

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420 Progression-free survival and biomarker correlates of response with BEMPEG plus NIVO in previously untreated patients with metastatic melanoma: results from the PIVOT-02 study, Adi Diab, Scott Tykodi, Gregory Daniels, Michele Maio, Brendan Curti, Karl Lewis, Sekwon Jang, Ewa Kalinka, Igor Puzanov, Alexander Spira, Daniel Cho, Shanhong Guan, Erika Puente, Ute Hoch, Sue Currie, Tuan Nguyen, Wei Lin, Mary Tagliaferri, Jonathan Zalevsky, Mario Sznol, and Michawl Hurwitz

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Autologous mastectomy reconstruction: Communication among the breast surgery team to maximize aesthetic and oncologic outcome., Brian P Dickinson, Dennis Holmes, Nikkie Vu-Huynh, Monica B Vu, Lincoln Snyder, Heather MacDonald, Lisa Guerra, Colleen Coleman, Crystal Fancher, Nahid Hamoui, Sadia Khan, Sadie Kim, January Lopez, Jennifer Overstreet, and Peter H Ashjian

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Disparities in Amputation Rates for Non-metastatic Extremity Soft Tissue Sarcomas and the Impact on Survival., Joshua C Dilday, Daniel W Nelson, Trevan D Fischer, and Melanie Goldfarb

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Genomic, proteomic, and immunologic associations with a durable complete remission of measurable metastatic melanoma induced by a patient-specific dendritic cell vaccine., Robert O Dillman, Gabriel I Nistor, and Aleksandra J Poole

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Glioblastoma Multiforme Stem Cell Cycle Arrest by Alkylaminophenol Through the Modulation of EGFR and CSC Signaling Pathways., Phuong Doan, Aliyu Musa, Akshaya Murugesan, Vili Sipilä, Nuno R Candeias, Frank Emmert-Streib, Pekka Ruusuvuori, Kirsi Granberg, Olli Yli-Harja, and Meenakshisundaram Kandhavelu

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Evolution of a 4-Benzyloxy-benzylamino Chemotype to Provide Efficacious, Potent, and Isoform Selective PPARα Agonists as Leads for Retinal Disorders., Xiaozheng Dou, Dinesh Nath, Henry Shin, Elmar Nurmemmedov, Philip C Bourne, Jian-Xing Ma, and Adam S Duerfeldt

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Scrotal and Penile Erythrodysesthesia Associated with Neoadjuvant Capecitabine Chemoradiation., Julie Dricken, Erica Pettke, John A Griffin, Henry Y Li, and Vivek Mehta

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CRI iAtlas: an interactive portal for immuno-oncology research., James A Eddy, Vésteinn Thorsson, Andrew E Lamb, David L Gibbs, Carolina Heimann, Jia Xin Yu, Verena Chung, Yooree Chae, Kristen Dang, Benjamin G Vincent, Ilya Shmulevich, and Justin Guinney

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A phase II, open-label study of tomivosertib (eFT508) added on to continued checkpoint inhibitor therapy in patients (pts) with insufficient response to single-agent treatment., Anthony B. El-Khoueiry, Nishan Tchekmedyian, Rachel E Sanborn, Julio Antonio Peguero, Kerry Pulver, Vekas Dembla, Jacob Stephen Thomas, Gary Gene Chiang, Mark Densel, Neil Sankar, Stephen Theodore Worland, Lyon L. Gleich, and Robert S. Sikorski

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418 A phase 1, dose escalation and dose expansion study of SQZ PBMC HPV as monotherapy and in combination with atezolizumab in HLA-A*02+ Patients with HPV16+ recurrent, or metastatic solid tumors, Cathy Eng, Joaquina Baranda, Matthew H Taylor, Michael Gordon, Ursula Matulonis, Filip Janku, Martin Kornacker, Asha Kamat, Oliver Rosen, and Antonio Jimeno

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418 A phase 1, dose escalation and dose expansion study of SQZ PBMC HPV as monotherapy and in combination with atezolizumab in HLA-A*02+ Patients with HPV16+ recurrent, or metastatic solid tumors, Cathy Eng, Joaquina Baranda, Matthew H Taylor, Michael Gordon, Ursula Matulonis, Filip Janku, Martin Kornacker, Asha Kamat, Oliver Rosen, and Antonio Jimeno

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Real-world burden of myelosuppression in patients with small cell lung cancer (SCLC): Retrospective, longitudinal data analysis., Robert S. Epstein, JoAnn Krenitsky, Roshanthi Weerasinghe, Amy S. Parrish, Rachel E Sanborn, and Tehseen Salimi

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Design of Development Candidate eFT226, a First in Class Inhibitor of Eukaryotic Initiation Factor 4A RNA Helicase., Justin T Ernst, Peggy A Thompson, Christian Nilewski, Paul A Sprengeler, Samuel Sperry, Garrick Packard, Theodore Michels, Alan Xiang, Chinh Tran, Christopher J Wegerski, Boreth Eam, Nathan P Young, Sarah Fish, Joan Chen, Haleigh Howard, Jocelyn Staunton, Jolene Molter, Jeff Clarine, Andres Nevarez, Gary G Chiang, Jim R Appleman, Kevin R Webster, and Siegfried H Reich

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The Combative Language of Cancer: A Plea for an Armistice., Matthew J Farrell

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799 Durable responses and immune activation with intratumoral electroporation of pIL-12 plus pembrolizumab in actively progressing anti-PD-1 refractory advanced melanoma: KEYNOTE 695 interim data, Pablo Fernandez-Penas, Matteo Carlino, Katy Tsai, Victoria Atkinson, Monaster Shaheen, Sajeve Thomas, Catalin Mihalcioiu, Tom Van Hagen, Rachel Roberts-Thomson, Andrew Haydon, Andrew Mant, Marcus Butler, Gregory Daniels, Elizabeth Buchbinder, John Hyngstrom, Mecker Moller, Igor Puzanov, C Lance Cowey, Eric Whitman, Carmen Ballesteros-Merino, Shawn M. Jensen, Bernard A Fox, Emmett Schmidt, Clemens Krepler, Scott Diede, Erica Browning, Reneta Hermiz, Lauren Svenson, Jon Salazar, Jack Lee, Christopher Baker, Donna Bannavong, Jendy Sell, Kellie Malloy Foerter, David Canton, Sandra Aung, Christopher Twitty, Alain Algazi, and Adil Daud

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799 Durable responses and immune activation with intratumoral electroporation of pIL-12 plus pembrolizumab in actively progressing anti-PD-1 refractory advanced melanoma: KEYNOTE 695 interim data, Pablo Fernandez-Penas, Matteo Carlino, Katy Tsai, Victoria Atkinson, Monater Shaheen, Sajeve Thomas, Catalin Mihalcioiu, Tom Van Hagen, Rachel Roberts-Thomson, Andrew Haydon, Andrew Mant, Marcus Butler, Gregory Daniels, Elizabeth Buchbinder, John Hyngstrom, Mecker Moller, Igor Puzanov, C Lance Cowey, Eric Whitman, Carmen Ballesteros-Merino, Shawn M. Jensen, Bernard A Fox, Emmett Schmidt, Clemens Krepler, Scott Diede, Erica Browning, Reneta Hermiz, Lauren Svenson, Jon Salazar, Jack Lee, Christopher Baker, Donna Bannavong, Jendy Sell, Kellie Malloy Foerter, David Canton, Sandra Aung, Christopher Twitty, Alain Algazi, and Adil Daud

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A novel surgeon credentialing and quality assurance process using transoral surgery for oropharyngeal cancer in ECOG-ACRIN Cancer Research Group Trial E3311., Robert L Ferris, Yael Flamand, F Christopher Holsinger, Gregory S Weinstein, Harry Quon, Ranee Mehra, Joaquin J Garcia, Michael L Hinni, Neil D Gross, Erich M Sturgis, Umamaheswar Duvvuri, Eduardo Méndez, John A Ridge, J Scott Magnuson, Kerry A Higgins, Mihir R Patel, Russel B Smith, Daniel W Karakla, Michael E Kupferman, James P Malone, Benjamin L Judson, Jeremy Richmon, Jay O Boyle, Rodrigo Bayon, Bert W O'Malley, Enver Ozer, Giovana R Thomas, Wayne M Koch, Richard Bryan Bell, Nabil F Saba, Shuli Li, Elin R Sigurdson, and Barbara Burtness

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Transoral robotic surgical resection followed by randomization to low- or standard-dose IMRT in resectable p16+ locally advanced oropharynx cancer: A trial of the ECOG-ACRIN Cancer Research Group (E3311)., Robert L. Ferris, Yael Flamand, Gregory S. Weinstein, Shuli Li, Harry Quon, Ranee Mehra, Joaquin J. Garcia, Christine H. Chung, Maura L. Gillison, Umamaheswar Duvvuri, Bert W. O'Malley, Enver Ozer, Giovanna R. Thomas, Wayne Koch, Michael Elliot Kupferman, Richard Bryan Bell, Nabil F. Saba, Miriam Lango, Eduardo Mendez, and Barbara Burtness

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The Efficacy of Passive Valve Antimicrobial Swab Caps Against Existing Clabsi Prevention Bundle in an Adult Hematology Inpatient Population: A Quality Improvement Initiative, Joseph F. Ferry, Neil Bailey, Vanessa Dunleavy, Joanna Fesler, Judson Hall, Sonia Glennie, William Bensinger, Raya Mawad, Krish Patel, Daniel N Egan, John M Pagel, and Livia Hegerova

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Resolution of eicosanoid/cytokine storm prevents carcinogen and inflammation-initiated hepatocellular cancer progression., Anna Fishbein, Weicang Wang, Haixia Yang, Jun Yang, Victoria M Hallisey, Jianjun Deng, Sanne M L Verheul, Sung Hee Hwang, Allison Gartung, Yuxin Wang, Diane R Bielenberg, Sui Huang, Mark W Kieran, Bruce D Hammock, and Dipak Panigrahy

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Cetuximab in Patients with Breast Cancer, Non-Small Cell Lung Cancer, and Ovarian Cancer Without KRAS, NRAS, or BRAF Mutations: Results from the Targeted Agent and Profiling Utilization Registry (TAPUR) Study., Julie G Fisher, David Tait, Elizabeth Garrett-Mayer, Susan Halabi, Pam K Mangat, Julian C Schink, Ricardo H Alvarez, Dan Veljovich, Timothy L Cannon, Pamela A Crilley, Theodore Pollock, Carmen J Calfa, Tareq Al Baghdadi, Ramya Thota, Nicole Fleming, Jared A Cotta, Andrew L Rygiel, Sasha L Warren, and Richard L Schilsky

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Colon and Rectal Surgery Robotic Training Programs: An Evaluation of Gender Disparities., Katherine E Foley, Kevin M Izquierdo, Madrigal G von Muchow, Amir Bastawrous, Robert K Cleary, and Mark K Soliman

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A profile on the FoundationFocus CDxBRCA tests., Lindsey Ford, Juliet E Wolford, Sandra Brown, and Leslie M Randall

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The combination of ibrutinib and rituximab demonstrates activity in first-line follicular lymphoma., Nathan H Fowler, Loretta Nastoupil, Sven De Vos, Mark Knapp, Ian W Flinn, Robert Chen, Ranjana H Advani, Sumeet Bhatia, Peter Martin, Raul Mena, Richard Eric Davis, Sattva S Neelapu, Karl Eckert, Jerry Ping, Melannie Co, Darrin M Beaupre, Jutta K Neuenburg, and M Lia Palomba

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Cancer vaccines yesterday, today, and tomorrow: Cinderella no more?, Bernard A Fox

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Immunotherapy-induced anti-cancer responses, Bernard A Fox

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Immunotherapy-Induced Anti-Cancer Responses, Bernard A Fox

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443 An immunotherapy trio in advanced HNSCC for coordinated B and T cell antigen response, Bernard A Fox, Tarsem Moudgil, Traci Hilton, Noriko Iwamoto, Christopher Paustian, Adi Mehta, Fridtjof Lund-Johansen, Rachel E Sanborn, Richard Bryan Bell, Madeleine Laws, Glenna McDonnell, Yoshinobu Koguchi, Carlo Bifulco, Brian D. Piening, Carmen Ballesteros-Merino, Shawn M. Jensen, Takashi Shimada, Hong-Ming Hu, Walter Urba, Rom Leidner, and Marcus Couey

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443 An immunotherapy trio in advanced HNSCC for coordinated B and T cell antigen response, Bernard A Fox, Tarsem Moudgil, Traci Hilton, Noriko Iwamoto, Christopher Paustian, Adi Mehta, Fridtjof Lund-Johansen, Rachel E Sanborn, Richard Bryan Bell, Madeline Laws, Glenna McDonnell, Yoshinobu Koguchi, Carlo Bifulco, Brian D. Piening, Carmen Ballesteros-Merino, Shawn M. Jensen, Takashi Shimada, Hong-Ming Hu, Walter Urba, Rom Leidner, and Marcus Couey

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Immunoscore as a parameter predicting time to recurrence and disease-free survival in T4N0 stage II colon cancer patients., Jerome Galon, Fabienne Hermitte, Bernhard Mlecnik, Alessandro Lugli, Carlo Bifulco, Iris D. Nagtegaal, Arndt Hartmann, Florence Marliot, Marc Van Den Eynde, Michael H.A. Roehrl, Pamela S. Ohashi, Eva Zavadova, Toshihiko Torigoe, Prabhudas S. Patel, Yili Wang, Yutaka Kawakami, Francesco Marincola, Paolo Antonio Ascierto, Bernard A Fox, and Franck Pages

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Prognostic Impact and Utility of Immunoprofiling in the Selection of Patients with Colorectal Peritoneal Carcinomatosis for Cytoreductive Surgery (CRS) and Heated Intraperitoneal Chemotherapy (HIPEC)., Mary Garland-Kledzik, Abhineet Uppal, Yalda Naeini, Stacey L Stern, Richard Erali, Anthony J Scholer, Adam Khader, Juan A Santamaria-Barria, Kathleen Cummins-Perry, Yi Zhou, Konstantinos I Votanopoulos, Perry Shen, Edward A Levine, and Anton J Bilchik

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Prior tonsillectomy is associated with an increased risk of esophageal adenocarcinoma., Katherine S Garman, Teminioluwa A Ajayi, Harold J Boutte, Shih-Ting Chiu, Richard J von Furstenberg, Benjamin R Lloyd, Cecelia Zhang, Mark W Onaitis, Shein-Chung Chow, and Shannon J McCall

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1074TiP SGNTGT-001: A phase I study of SGN-TGT, an effector-function enhanced monoclonal antibody (mAb), in advanced malignancies, E Garralda, Rachel E Sanborn, AR Minchom, D Davar, G Curigliano, V Ribrag, A Mehta, F Foss, P Garfin, and S Ansell

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Management of early hepatocellular carcinoma: results of the Delphi consensus process of the Americas Hepato-Pancreato-Biliary Association., Sepideh Gholami, Lauren M Perry, Jason W Denbo, Kenneth Chavin, Philippa H Newell, Quan Ly, Charles St Hill, Gareth Morris-Stiff, Jonathan Kessler, Timothy L Frankel, Neehar D Parikh, Prejesh Philips, George Salti, Toms Augustin, Federico Aucejo, Meelie Debroy, Natalie Coburn, and Susanne G Warner

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Life Is Really Simple, but We Insist on Making It Complicated-Lessons From Confucius on Ultrasound Use in the ICU., Christopher R Gilbert, Fabien Maldonado, Lonny B Yarmus, Jason A Akulian, Candice Wilshire, and Jed A Gorden

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Life Is Really Simple, but We Insist on Making It Complicated-Lessons From Confucius on Ultrasound Use in the ICU., Christopher R Gilbert, Fabien Maldonado, Lonny B Yarmus, Jason A Akulian, Candice Wilshire, and Jed A Gorden

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Poor Monitor Screen Height Positioning by Pulmonologists During Flexible Bronchoscopy: A Nested, Prospective Observational Trial., Christopher R Gilbert, Jeffrey Thiboutot, Alexander Chen, A Christine Argento, Nicholas J Pastis, Hans J Lee, Andrew D Lerner, and Lonny B Yarmus

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Assessment of Ergonomic Strain and Positioning During Bronchoscopic Procedures: A Feasibility Study., Christopher R Gilbert, Jeffrey Thiboutot, Christopher Mallow, Alexander Chen, Nicholas J Pastis, A Christine Argento, Jennifer Millar, Robert A Lavin, Andrew D Lerner, Diana H Yu, Ben Salwen, Daniel Lunz, Hans J Lee, and Lonny B Yarmus

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Management of Indwelling Tunneled Pleural Catheters: A Modified Delphi Consensus Statement., Christopher R Gilbert, Momen M Wahidi, Richard W Light, M Patricia Rivera, Daniel H Sterman, Rajesh Thomas, Samira Shojaee, Shmuel Shoham, Ionnis Psallidas, David E Ost, Daniela Molena, Nick Maskell, Fabien Maldonado, Moishe Liberman, Y C Gary Lee, Hans Lee, Felix J F Herth, Horiana Grosu, Jed A Gorden, Edward T H Fysh, John P Corcoran, A Christine Argento, Jason A Akulian, Najib M Rahman, and Lonny B Yarmus

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Part One: 2. Screening and Early Detection, Jaya M. Gill Ed.

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Disparities in the Occurrence of Late Effects following Treatment among Adolescent and Young Adult Melanoma Survivors., Alicia A Gingrich, Candice A M Sauder, Melanie Goldfarb, Qian Li, Ted Wun, and Theresa H M Keegan

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Safety and Clinical Activity of MEDI0562, a Humanized OX40 Agonist Monoclonal Antibody, in Adult Patients with Advanced Solid Tumors., Bonnie S Glisson, Rom Leidner, Robert L Ferris, John Powderly, Naiyer A Rizvi, Bhumsuk Keam, Reva Schneider, Sanjay Goel, James P Ohr, Jennifer Burton, Yanan Zheng, Steven Eck, Matthew Gribbin, Katie Streicher, Danielle M Townsley, and Sandip Pravin Patel

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Outcomes of Treatment with the Chimeric Antigen Receptor (CAR) T Cell Therapy Lisocabtagene Maraleucel (liso-cel) in the Nonuniversity Setting: Initial Results from the Outreach Study, John E Godwin, Cesar O. Freytes, Michael Maris, Don A. Stevens, Daanish Hoda, Bassam Mattar, Juan C. Varela, Mohamad Cherry, James Essell, Jay Courtright, Suzanne R. Fanning, Habte A. Yimer, Nikolaus S. Trede, Marina Youssef, James Lymp, and Carlos Bachier

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Blood test shows high accuracy in detecting stage I non-small cell lung cancer., Cherylle Goebel, Christopher L Louden, Robert McKenna, Osita Onugha, Andrew Wachtel, and Thomas Long

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Recent advances in the understanding and management of primary hyperparathyroidism., Melanie Goldfarb and Frederick R Singer

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Safety and tolerability of MEDI0562 in combination with durvalumab or tremelimumab in patients with advanced solid tumors., Jonathan Wade Goldman, Sarina Anne Piha-Paul, Brendan Curti, Katrina Pedersen, Todd Michael Bauer, Stefanie L. Groenland, Richard D. Carvajal, Vaishali Chhaya, Scott A. Hammond, Katie Streicher, Danielle Michelle Townsley, Young Kwang Chae, Jens Voortman, Aurelien Marabelle, and John D. Powderly

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Safety and tolerability of MEDI0562 in combination with durvalumab or tremelimumab in patients with advanced solid tumors., Jonathan Wade Goldman, Sarina Anne Piha-Paul, Brendan Curti, Katrina Pedersen, Todd Michael Bauer, Stefanie L. Groenland, Richard D. Carvajal, Vaishali Chhaya, Scott A. Hammond, Katie Streicher, Danielle Michelle Townsley, Young Kwang Chae, Jens Voortman, Aurelien Marabelle, and John D. Powderly

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CT191 - Interim results from CLASSICAL-Lung, phase 1b/2 study of pepinemab (VX15/2503) in combination with avelumab in advanced NSCLC, Jonathan W. Goldman, Terrence L. Fisher, Elizabeth Evans, John E. Leonard, Desa Rae Pastore, Crystal Mallow, Ernest Smith, Andreas Schroder, Kevin Chin, Michael Shafique, Thaddeus Beck, Megan A. Baumgart, Ramaswamy Govindan, Nashat Gabrail, Rachel E Sanborn, Alexander Spira, Nagashree Seetharamu, Yanyan Lou, Aaron S. Mansfield, and Maurice Zauderer

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Abstract CT191: Interim results from CLASSICAL-Lung, phase 1b/2 study of pepinemab (VX15/2503) in combination with avelumab in advanced NSCLC, Jonathan W. Goldman, Terrence L. Fisher, Elizabeth Evans, John E. Leonard, Desa Rae Pastore, Crystal Mallow, Ernest Smith, Andreas Schroeder, Kevin Chin, Michael Shafique, Thaddeaus Beck, Megan A. Baumgart, Ramaswamy Govindan, Nashat Gabrail, Rachel E Sanborn, Alexander I. Spira, Nagashree Seetharamu, Yanyan Lou, Aaron S. Mansfield, and Maurice Zauderer

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Utilization of Claims Data in Research: Are We Missing the Forest and the Trees?, Jed A Gorden, Candice Wilshire, and Christopher R Gilbert

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Using Preclinical Data to Design Combination Clinical Trials of Radiation Therapy and Immunotherapy., Michael J. Gough, Shay Sharon, Marka R Crittenden, and Kristina H Young

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Using Preclinical Data to Design Combination Clinical Trials of Radiation Therapy and Immunotherapy., Michael J. Gough, Shay Sharon, Marka R Crittenden, and Kristina H Young

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Prospective Study of Use of Edmonton Symptom Assessment Scale Versus Routine Symptom Management During Weekly Radiation Treatment Visits., Uma D Goyal, Kristen Riegert, Rajayogesh Davuluri, Shawn Ong, Sun K Yi, Shona T Dougherty, and Charles C Hsu

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Pembrolizumab immunotherapy for relapsed CNS Lymphoma., Jerome J Graber, Benjamin Plato, Raya Mawad, and Daniel J Moore

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A phase II single-arm study of pembrolizumab with enzalutamide in men with metastatic castration-resistant prostate cancer progressing on enzalutamide alone., Julie N Graff, Tomasz M Beer, Joshi J Alumkal, Rachel E Slottke, William L. Redmond, George V Thomas, Reid F Thompson, Mary A Wood, Yoshinobu Koguchi, Yiyi Chen, Emile Latour, Raymond C Bergan, Charles G Drake, and Amy E Moran

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Conserved Interferon-γ Signaling Drives Clinical Response to Immune Checkpoint Blockade Therapy in Melanoma., Catherine S Grasso, Jennifer Tsoi, Mykola Onyshchenko, Gabriel Abril-Rodriguez, Petra Ross-Macdonald, Megan Wind-Rotolo, Ameya Champhekar, Egmidio Medina, Davis Y Torrejon, Daniel Sanghoon Shin, Phuong Tran, Yeon Joo Kim, Cristina Puig-Saus, Katie Campbell, Agustin Vega-Crespo, Michael Quist, Christophe Martignier, Jason J Luke, Jedd D Wolchok, Douglas B Johnson, Bartosz Chmielowski, F Stephen Hodi, Shailender Bhatia, William Sharfman, Walter Urba, Craig L Slingluff, Adi Diab, John B A G Haanen, Salvador Martin Algarra, Drew M Pardoll, Valsamo Anagnostou, Suzanne L Topalian, Victor E Velculescu, Daniel E Speiser, Anusha Kalbasi, and Antoni Ribas

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Comprehensive guidance on the diagnosis and management of primary mesenchymal tumours of the thyroid gland., Sriram Gubbi, Shilpa Thakur, Shirisha Avadhanula, Katherine A Araque, Armando C Filie, Mark Raffeld, James Welch, Jaydira Del Rivero, Electron Kebebew, Kenneth D Burman, Leonard Wartofsky, and Joanna Klubo-Gwiezdzinska

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Germinal centers in tertiary lymphoid structures distinguish long-term pancreatic cancer survivors associated with neoantigen expression and immune memory, Andrew J Gunderson

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TGFβ suppresses CD8+ T cell expression of CXCR3 and tumor trafficking., Andrew J Gunderson, Tomoko Yamazaki, Kayla McCarty, Nathaniel E Fox, Michaela Phillips, Alejandro F Alice, Tiffany Blair, Mark Whiteford, David O'Brien, Rehan Ahmad, Maria X Kiely, Amanda Hayman, Todd Crocenzi, Michael J. Gough, Marka R. Crittenden, and Kristina H Young

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Novel application of vinylpolysiloxane hearing aid impression mold as patient-specific bolus for head and neck cancer radiotherapy., Anne Elizabeth Gunter, John Burgoyne, Min Park, Namou Kim, Daliang Cao, and Vivek Mehta

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Initial and Consolidation Therapy for Younger Patients with Mantle Cell Lymphoma., Daniel Guy and Brad S Kahl

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Surveillance for second breast cancer events in women with a personal history of breast cancer using breast MRI: a systematic review and meta-analysis., Cameron B Haas, Larissa Nekhlyudov, Janie M Lee, Sara H Javid, Mary Bush, Dianne Johnson, Timothy Gleason, Cary Kaufman, Jennifer Specht, Sean Stitham, and Karen J Wernli

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The importance of age as prognostic factor for the outcome of patients with hepatoblastoma: Analysis from the Children's Hepatic tumors International Collaboration (CHIC) database., Beate Haeberle, Arun Rangaswami, Mark Krailo, Piotr Czauderna, Eiso Hiyama, Rudolf Maibach, Dolores Lopez-Terrada, Daniel C Aronson, Rita Alaggio, Marc Ansari, Marcio H Malogolowkin, Giorgio Perilongo, Allison F O'Neill, Angela Trobaugh-Lotrario, Kenichiro Watanabe, Irene Schmid, Dietrich von Schweinitz, Sarangarajan Ranganathan, Kenichi Yoshimura, Tomoro Hishiki, Yukichi Tanaka, Jin Piao, Yurong Feng, Eugenia Rinaldi, Davide Saraceno, Marisa Derosa, and Rebecka L Meyers

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Organ Preservation in the Treatment of Stage II and III Rectal Cancer., Ed Hagen and Robert K Cleary

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Perianal basal cell carcinoma: a common cancer in an uncommon location., Ed Hagen, Nathan Hite, John A Griffin, and Rodney Kratz

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Laparoscopic Transhiatal Esophagectomy for Invasive Esophageal Adenocarcinoma., Kelly R Haisley, Walaa F Abdelmoaty, and Christy M Dunst

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Results of Lung Cancer Screening in the Community., John R Handy, Michael Skokan, Erika Rauch, Steven Zinck, Rachel E Sanborn, Svetlana Kotova, and Mansen Wang

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Results of Lung Cancer Screening in the Community., John R Handy, Michael Skokan, Erika Rauch, Steven Zinck, Rachel E Sanborn, Svetlana Kotova, and Mansen Wang

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How we treat left-sided vs right-sided colon cancer., Diana L Hanna and Heinz-Josef Lenz

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INDUCE-3: A randomized, double-blind study of GSK3359609 (GSK609), an inducible T-cell co-stimulatory (ICOS) agonist antibody, plus pembrolizumab (PE) versus placebo (PL) plus PE for first-line treatment of PD-L1-positive recurrent/metastatic head and neck squamous cell carcinoma (R/M HNSCC)., Aaron Richard Hansen, Thomas Stanton, Min Hee Hong, Ezra EW Cohen, Hisham Mohamed Mehanna, Michael Jon Chisamore, David Turner, Sapna Yadavilli, Kelly Bell, Carlos Baccan, Rosalida Leone, Helen Chen, Helen Zhou, Catherine Elizabeth Ellis, Marc S. Ballas, Axel Hoos, and Danny Rischin

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Three-Dimensional Computer-Assisted Surgical Planning, Manufacturing, and Intraoperative Navigation in Oncologic Surgery., Phillip Harrison, Ashish Patel, Allen C Cheng, and Richard Bryan Bell

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The Effects of Music Medicine on Reducing Distress, Anxiety, and Pain During Bone Marrow Biopsy Procedures, Betsy Hartman, Sharon Mast, and Judy Delismon

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Use of Convalescent Plasma in Hospitalized Patients with Covid-19 - Case Series., Livia Hegerova, Ted Gooley, Kelly A Sweerus, Cynthia L Maree, Neil Bailey, Megumi Bailey, Vanessa Dunleavy, Krish Patel, Kirsten Alcorn, N Rebecca Haley, Jill M Johnsen, Barbara A Konkle, Annamarie C Lahti, Morgan L Alexander, Jason D Goldman, Anne B Lipke, Sun-Jung Lim, Mark David Sullivan, John S Pauk, and John M Pagel

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An atypical case of necrotizing fasciitis secondary to perforated cecal cancer., Laura S Heidelberg, Erica Pettke, Teresa E Wagner, and Lauren Angotti

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Simultaneously spatial and temporal Higher-Order Total Variations for noise suppression and motion reduction in DCE and IVIM., Renjie He, Yao Ding, Abdallah S R Mohamed, Sweet Ping Ng, Rachel B Ger, Hesham Elhalawani, Baher A Elgohari, Kristina H Young, Katherine A Hutcheson, Clifton D Fuller, and Stephen Y Lai

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Cellular thermal shift analysis for interrogation of CRISPR-assisted proteomic changes., Nam-Gu Her, Ivan Babic, Venkata Yenugonda, Santosh Kesari, and Elmar Nurmemmedov

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Thrombospondin-1 counteracts the p97 inhibitor CB-5083 in colon carcinoma cells., Nam-Gu Her, Santosh Kesari, and Elmar Nurmemmedov

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Stapled Diaphragmatic Plication: Is It Better Than Suture Plication?, Terra M Hill and Osita Onugha

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Allogeneic autophagosome-enriched composition for the treatment of disease, Traci Hilton, Sandra Aung, Rieneke van de Ven, Christopher Paustian, Tarsem Moudgil, Christopher Dubay, Christopher Twitty, Hong-Ming Hu, and Bernard A Fox

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Allogeneic autophagosome-enriched composition for the treatment of disease, Traci Hilton, Sandra Aung, Rieneke van de Ven, Christopher Paustian, Tarsem Moudgil, Christopher Dubay, Christopher Twitty, Hong-Ming Hu, and Bernard A Fox

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Allogeneic autophagosome-enriched composition for the treatment of disease, Traci Hilton, Sandra Aung, Rieneke van de Ven, Christopher Paustian, Tarsem Moudgil, Christopher Dubay, Christopher Twitty, Hong-Ming Hu, and Bernard A Fox

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Allogeneic autophagosome-enriched composition for the treatment of disease, Traci Hilton, Sandra Aung, Rieneke van de Ven, Christopher Paustian, Tarsem Moudgil, Christopher Dubay, Christopher Twitty, Hong-Ming Hu, and Bernard A Fox

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Simultaneous Isolation of Circulating Nucleic Acids and EV-Associated Protein Biomarkers From Unprocessed Plasma Using an AC Electrokinetics-Based Platform., Juan Pablo Hinestrosa, David J Searson, Jean M Lewis, Alfred Kinana, Orlando Perrera, Irina Dobrovolskaia, Kevin Tran, Robert Turner, Heath I Balcer, Iryna Clark, David Bodkin, Dave Hoon, and Rajaram Krishnan

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Breast cancer care during a pandemic: an opportune time for cryoablation?, Dennis R Holmes

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Patients With Natural Killer (NK) Cell Chronic Active Epstein-Barr Virus Have Immature NK Cells and Hyperactivation of PI3K/Akt/mTOR and STAT1 Pathways., Matthew K Howe, Kennichi Dowdell, Hye Sun Kuehn, Qingxue Li, Geoffrey T Hart, Doreen Garabedian, Kelly Liepshutz, Amy P Hsu, Hua Su, Julie E Niemela, Jennifer L Stoddard, Gulbu Uzel, Evan Shereck, Laura Schulz, Tatyana Feldman, Sergio D Rosenzweig, Eric O Long, Lesia Dropulic, and Jeffrey I Cohen

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Complete response with talimogene laherparepvec in recurrent melanoma of the ear: A case report., Ashley C Hsu, Niels C Kokot, Burton L Eisenberg, and Jacob S Thomas

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SITC cancer immunotherapy resource document: a compass in the land of biomarker discovery., Siwen Hu-Lieskovan, Srabani Bhaumik, Kavita Dhodapkar, Jean-Charles J B Grivel, Sumati Gupta, Brent A Hanks, Sylvia Janetzki, Thomas O Kleen, Yoshinobu Koguchi, Amanda W Lund, Cristina Maccalli, Yolanda D Mahnke, Ruslan D Novosiadly, Senthamil R Selvan, Tasha Sims, Yingdong Zhao, and Holden T Maecker

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Cumulative suppressive index as a predictor of relapse free survival and overall survival in Human Papilloma Virus-negative oral squamous cell carcinomas with negative resection margins., Lauren Hum, Daniel Bethmann, Zipei Feng, Shu-Ching Chang, Alexander Eckert, Carmen Ballesteros-Merino, Claudia Keschke, Matthias Kappler, Carlo Bifulco, Claudia Wickenhauser, Barbara Seliger, Bernard A Fox, and Richard Bryan Bell

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Survival with Olaparib in Metastatic Castration-Resistant Prostate Cancer., Maha Hussain, Joaquin Mateo, Karim Fizazi, Fred Saad, Neal Shore, Shahneen Sandhu, Kim N Chi, Oliver Sartor, Neeraj Agarwal, David Olmos, Antoine Thiery-Vuillemin, Przemyslaw Twardowski, Guilhem Roubaud, Mustafa Özgüroğlu, Jinyu Kang, Joseph Burgents, Christopher Gresty, Claire Corcoran, Carrie A Adelman, and Johann de Bono

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Building a circular RNA centered gene regulation network associated with cervical squamous cell carcinoma., Wei Hu, Qingqing Li, Xiaoyi He, Ming Gao, Zhanfu Zheng, Yuanlin Ding, Kai Wang, and Yuqing He