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Submissions from 2021

Immunotherapy Combos: LAG-3, TIM-3, TIGIT, OX-40, Rachel E Sanborn

OncLive Data Review: ESMO Congress 2021, Rachel E Sanborn

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A phase 1 dose-escalation study of a PD-L1xCD27 bispecific antibody CDX-527 in patients with advanced malignancies., Rachel E Sanborn, Rodolfo E. Bordoni, and See author list in comments

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Sanborn and Gaffar Share Clinical and Economic Treatment Insights in NSCLC, Rachel E Sanborn and Yousuf A. Gaffar

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CX-072 (pacmilimab), a Probody PD-L1 inhibitor, in combination with ipilimumab in patients with advanced solid tumors (PROCLAIM-CX-072): a first-in-human, dose-finding study., Rachel E Sanborn, Omid Hamid, Elisabeth Ge de Vries, Patrick A Ott, Javier Garcia-Corbacho, Valentina Boni, Johanna Bendell, Karen A Autio, Daniel C Cho, Ruth Plummer, Mark Stroh, Lawrence Lu, and Fiona Thistlethwaite

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398 neoIRX: a phase II trial of locoregional cytokine therapy to promote immunologic priming and clinical response to neoadjuvant pembrolizumab plus chemotherapy in triple negative breast cancer (TNBC), Katherine Sanchez, Alison Conlin, Parvin Peddi, Sasha Stanton, Janet Ruzich, Kelly S Perlewitz, Yaping Wu, Nikki Moxon, Staci Mellinger, Zhaoyu Sun, William L. Redmond, and David B Page

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OT1-18-03. The neoIRX trial:locoregional cytokine therapy to promote immunologic priming and enhanced response to neoadjuvant pembrolizumab plus chemotherapy in triple negative breast cancer (TNBC), Katherine Sanchez, Alison Conlin, Parvin Peddi, Sasha Stanton, Janet Ruzich, Kelly S Perlewitz, Yaping Wu, Nikki Moxon, Staci Mellinger, Zhaoyu Sun, William L. Redmond, and David B Page

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Multiplex immunofluorescence to measure dynamic changes in tumor-infiltrating lymphocytes and PD-L1 in early-stage breast cancer., Katherine Sanchez, Isaac Kim, Brie Chun, Joanna Pucilowska, William L. Redmond, Walter Urba, Maritza Martel, Yaping Wu, Mary Campbell, Zhaoyu Sun, Gary Grunkemeier, Shu-Ching Chang, Brady Bernard, and David B Page

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Increased Intracranial Pressure: The Use of an Individualized Ladder Approach., Marlon G Saria and Santosh Kesari

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Lifileucel, a Tumor-Infiltrating Lymphocyte Therapy, in Metastatic Melanoma., Amod A Sarnaik, Omid Hamid, Nikhil I Khushalani, Karl D Lewis, Theresa Medina, Harriet M Kluger, Sajeve S Thomas, Evidio Domingo-Musibay, Anna C Pavlick, Eric D Whitman, Salvador Martin-Algarra, Pippa Corrie, Brendan D Curti, Judit Oláh, Jose Lutzky, Jeffrey S Weber, James M G Larkin, Wen Shi, Toshimi Takamura, Madan Jagasia, Harry Qin, Xiao Wu, Cecile Chartier, Friedrich Graf Finckenstein, Maria Fardis, John M Kirkwood, and Jason A Chesney

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SmartPhrase: Development of an Electronic Health Record System to Promote Chemotherapy and Immunotherapy Safety., Mary Jo Sarver, Monica McManus, Amy Allen, Bethany Johnson, and Dennielle Padgett

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Development of a SmartPhrase in the electronic health record to promote chemotherapy and immunotherapy safety, Mary Jo Sarver, Monica McManus, Amy Allen, Bethany Johnson, Dennielle Padgett, and Elizabeth Ser

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Germline genetic contribution to the immune landscape of cancer., Rosalyn W Sayaman, Mohamad Saad, Vésteinn Thorsson, Donglei Hu, Wouter Hendrickx, Jessica Roelands, Eduard Porta-Pardo, Younes Mokrab, Farshad Farshidfar, Tomas Kirchhoff, Randy F Sweis, Oliver F Bathe, Carolina Heimann, Michael J Campbell, Cynthia Stretch, Scott Huntsman, Rebecca E Graff, Najeeb Syed, Laszlo Radvanyi, Simon Shelley, Denise Wolf, Francesco M Marincola, Michele Ceccarelli, Jérôme Galon, Elad Ziv, and Davide Bedognetti

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Testing the acceptability and feasibility of a tablet-based supportive cancer platform for patients with metastatic breast cancer., Kathryn H Schmitz, Erica Schleicher, Shawna Doerksen, Christina Truica, Leah Cream, Rena Kass, Michelle Farnan, Robin Suess, Brett Gordon, David S Zucker, and Michael Hayes

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Phase I trial of intranasal NEO100, highly purified perillyl alcohol, in adult patients with recurrent glioblastoma., Axel H Schönthal, David M Peereboom, Naveed Wagle, Rose Lai, Anna J Mathew, Kyle M Hurth, Vincent F Simmon, Steven P Howard, Lynne P Taylor, Frances Chow, Clovis O da Fonseca, and Thomas C Chen

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Pegfilgrastim Biosimilars: Where Are We Now?, Christopher Selby, Breanne Peyton-Thomas, and Parnian Eslami

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Influence of Socioeconomic Status on Incident Medical Conditions in Two-Year Survivors of Adolescent or Young Adult Differentiated Thyroid Cancer., Thomas J Semrad, Qian Li, Melanie Goldfarb, Alison Semrad, Michael Campbell, D Gregory Farwell, and Theresa H M Keegan

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A Phase Ib/II Study of Pepinemab in Combination with Avelumab in Advanced Non-Small Cell Lung Cancer., Michael R Shafique, Terrence L Fisher, Elizabeth E Evans, John E Leonard, Desa Rae E Pastore, Crystal L Mallow, Ernest Smith, Vikas Mishra, Andreas Schröder, Kevin M Chin, Joseph T Beck, Megan A Baumgart, Ramaswamy Govindan, Nashat Y Gabrail, Alexander I Spira, Nagashree Seetharamu, Yanyan Lou, Aaron S Mansfield, Rachel E Sanborn, Jonathan W Goldman, and Maurice Zauderer

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KTE-X19 anti-CD19 CAR T-cell therapy in adult relapsed/refractory acute lymphoblastic leukemia: ZUMA-3 phase 1 results., Bijal D Shah, Michael R Bishop, Olalekan O Oluwole, Aaron C Logan, Maria R Baer, William B Donnellan, Kristen M O'Dwyer, Houston Holmes, Martha L Arellano, Armin Ghobadi, John M Pagel, Yi Lin, Ryan D Cassaday, Jae Park, Mehrdad Abedi, Januario Castro, Daniel J DeAngelo, Adriana K Malone, Raya Mawad, Gary Schiller, John Michael Rossi, Adrian Bot, Tong Shen, Lovely Goyal, Rajul K Jain, Remus Vezan, and William George Wierda

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Correction to: The Clinical Utility of DCISionRT, Chirag Shah, Troy Bremer, Charles Cox, Pat Whitworth, Rakesh Patel, Anushka Patel, Eric Brown, Linsey Gold, David Rock, Lee Riley, Christy Kesslering, Sheree Brown, Robert Gabordi, James Pellicane, Rachel Rabinovich, Sadia Khan, Sandra Templeton, Lonika Majithia, Shawna C Willey, Fredrik Wärnberg, Naamit K Gerber, Steve Shivers, and Frank A Vicini

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The Clinical Utility of DCISionRT, Chirag Shah, Troy Bremer, Charles Cox, Pat Whitworth, Rakesh Patel, Anushka Patel, Eric Brown, Linsey Gold, David Rock, Lee Riley, Christy Kesslering, Sheree Brown, Robert Gabordi, James Pellicane, Rachel Rabinovich, Sadia Khan, Sandra Templeton, Lonika Majithia, Shawna C Willey, Fredrik Wärnberg, Naamit K Gerber, Steve Shivers, and Frank A Vicini

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Perspectives and Impacts of the Pending US Radiation Oncology Alternative Payment Model., Chirag Shah and Jeffery C Ward

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Gelatin methacrylate hydrogels culture model for glioblastoma cells enriches for mesenchymal-like state and models interactions with immune cells., Nameeta Shah, Pavan M Hallur, Raksha A Ganesh, Pranali Sonpatki, Divya Naik, Komal Prasad Chandrachari, Ralph B Puchalski, and Aditya Chaubey

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Genomic and Molecular Profiling of Human Papillomavirus Associated Head and Neck Squamous Cell Carcinoma Treated with Immune Checkpoint Blockade Compared to Survival Outcomes., Hira Shaikh, Julie E McGrath, Brittany Hughes, Joanne Xiu, Pavel Brodskiy, Ammar Sukari, Sourat Darabi, Chukwuemeka Ikpeazu, Chadi Nabhan, Wolfgang Michael Korn, and Trisha M Wise-Draper

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Plasma MMP-2 and MMP-7 levels are elevated first month after surgery and may promote growth of residual metastases., Hmc Shantha Kumara, Hiromichi Miyagaki, Sajith A Herath, Erica Pettke, Xiaohong Yan, Vesna Cekic, and Richard L Whelan

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Supportive care for patients with brain metastases from lung cancer., Akanksha Sharma and Maciej M Mrugala

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Updates on Molecular Targeted Therapies for Intraparenchymal CNS Metastases., Akanksha Sharma, Lauren Singer, and Priya Kumthekar

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A platform for locoregional T-cell immunotherapy to control HNSCC recurrence following tumor resection., Shay Sharon, Jason R Baird, Shelly Bambina, Gwen Kramer, Tiffany C Blair, Shawn M Jensen, Rom S Leidner, R Bryan Bell, Nardy Casap, Marka R Crittenden, and Michael J Gough

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Explant Modeling of the Immune Environment of Head and Neck Cancer., Shay Sharon, Thomas Duhen, Shelly Bambina, Jason Baird, Rom Leidner, Bryan Bell, Nardy Casap, Marka Crittenden, Swetha Vasudevan, Maria Jubran, Nataly Kravchenko-Balasha, and Michael Gough

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Open-label, phase II study of ladiratuzumab vedotin (LV) for castration-resistant prostate cancer (SGNLVA-005, trial-in-progress)., Amna Falak Sher, Justine Yang Bruce, Nashat Y. Gabrail, Ian Churchill Anderson, Anna Patrikidou, Rachel E Sanborn, Jae Yong Cho, Arielle Shebay Lee, Jong-Seok Lee, Louise M. Nott, Do-Youn Oh, Sang Cheul Oh, Sung Yong Oh, Yinghui Wang, Zejing Wang, and Troy H. Guthrie

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Current status of gastrointestinal tract cancer brain metastasis and the use of blood-based cancer biomarker biopsy., Yoshiaki Shoji, Satoru Furuhashi, Daniel F Kelly, Anton J Bilchik, Dave S B Hoon, and Matias A Bustos

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Impact of Comorbidities on Outcomes and Toxicity in Patients Treated with CAR T-Cell Therapy for Diffuse Large B Cell Lymphoma (DLBCL): A Multicenter Rwe Study, Geoffrey Shouse, Neil Bailey, Krish Patel, and See all authors in comments

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1193MO - Amivantamab plus lazertinib in post-osimertinib, post-platinum chemotherapy EGFR-mutant non-small cell lung cancer (NSCLC): Preliminary results from CHRYSALIS-2, CA Shu, K Goto, Y Ohe, B Besse, K Park, Y Wang, F Griesinger, JC Yang, E Felip, Rachel E Sanborn, R Bernabe Caro, JM Bauml, J Chen, E Fennema, J Mahoney, L Trani, RE Knoblauch, M Thayu, and BC Chou

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523 Preliminary clinical experience with XmAb20717, a PD-1 x CTLA-4 bispecific antibody, in patients with advanced solid tumors, Elaine Shum, Rom Leidner, and See full list of authors in comments

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Multicenter, double-blind, placebo-controlled trial of seviprotimut-L polyvalent melanoma vaccine in patients with post-resection melanoma at high risk of recurrence., Craig L Slingluff, Karl D Lewis, Robert Andtbacka, John Hyngstrom, Mohammed Milhem, Svetomir N Markovic, Tawnya Bowles, Omid Hamid, Leonel Hernandez-Aya, Joel Claveau, Sekwon Jang, Prejesh Philips, Shernan G Holtan, Montaser F Shaheen, Brendan Curti, William Schmidt, Marcus O Butler, Juan Paramo, Jose Lutzky, Arvinda Padmanabhan, Sajeve Thomas, Daniel Milton, Andrew Pecora, Takami Sato, Eddy Hsueh, Suprith Badarinath, John Keech, Sujith Kalmadi, Pallavi Kumar, Robert Weber, Edward Levine, Adam Berger, Anna Bar, J Thaddeus Beck, Jeffrey B Travers, Catalin Mihalcioiu, Brian Gastman, Peter Beitsch, Suthee Rapisuwon, John Glaspy, Edward C McCarron, Vinay Gupta, Deepti Behl, Brent Blumenstein, and Joanna J Peterkin

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Psychometric Characteristics and Validity of the PROMIS Cancer Function Brief 3D Profile., Sean R Smith, Mary Vargo, David Zucker, Samman Shahpar, Lynn Gerber, Maryanne Henderson, Gina Jay, Minji Lee, and Andrea Cheville

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Small molecules inhibitors of the heterogeneous ribonuclear protein A18 (hnRNP A18): a regulator of protein translation and an immune checkpoint., Eduardo Solano-Gonzalez, Katherine M Coburn, Wenbo Yu, Gerald M Wilson, Elmar Nurmemmedov, Santosh Kesari, Elizabeth T Chang, Alexander D MacKerell, David J Weber, and France Carrier

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Small molecules inhibitors of the heterogeneous ribonuclear protein A18 (hnRNP A18): a regulator of protein translation and an immune checkpoint., Eduardo Solano-Gonzalez, Katherine M Coburn, Wenbo Yu, Gerald M Wilson, Elmar Nurmemmedov, Santosh Kesari, Elizabeth T Chang, Alexander D MacKerell, David J Weber, and France Carrier

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Corrigendum to 'An Introduction to the Cyrcadia Breast Monitor: A Wearable Breast Health Monitoring Device'[Computer Methods and Programs in Biomedicine 197: 105758]., Vinitha Sree S, Rob Royea, Kevin J Buckman, Matt Benardis, Jim Holmes, Ronald L Fletcher, Ng Eyk, U Rajendra Acharya, and Joshua D I Ellenhorn

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Response to mRNA vaccination for COVID-19 among patients with multiple myeloma., Samuel D Stampfer, Marissa-Skye Goldwater, Scott Jew, Sean Bujarski, Bernard Regidor, David Daniely, Haiming Chen, Ning Xu, Mingjie Li, Tracy Green, Eddie Fung, Elias Aquino, Regina Swift, Shahrooz Eshaghian, Kurt Preugschat, Aaron J Feinstein, Tanya M Spektor, and James R Berenson

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Tumor-associated autoantibodies from mouse breast cancer models are found in serum of breast cancer patients., Sasha Stanton, Ekram Gad, Erik Ramos, Lauren Corulli, James Annis, Jennifer Childs, Hiroyuki Katayama, Samir Hanash, Jeffrey Marks, and Mary L Disis

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1556 - Retinoid X receptor agonists enhances Th1 antigen-specific and polyfunctional T cells with the HER2-IGFBP2-IGF1R vaccine, Sasha Stanton, Erin Rodmaker, Nicholas Drovetto, Lauren Corulli, Flonia Levy, Venkatram Atigadda, Clinton Grubbs, Romaine Fernando, Shizuko Sei, and Mary L. Disis

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The importance of low-dose CT screening to identify emphysema in asymptomatic participants with and without a prior diagnosis of COPD., David Steiger, M Faisal Siddiqi, Rowena Yip, David F Yankelevitz, Claudia I Henschke, I-ELCAP investigators, Ralph W Aye (I-ELCAP investigator), and Kristin Manning (I-ELCAP investigator)

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Global Proteomic Profiling Identifies Novel Prognostic Factors in Undifferentiated Leukemia Blasts from Patients with NPM1 Mutations: A Previously Unreported Approach to Biomarker Discovery from the Fred Hutch and SWOG, Derek Stirewalt, John E Godwin, and See full list of authors in comments

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Galectin-3 inhibition with belapectin combined with anti-OX40 therapy reprograms the tumor microenvironment to favor anti-tumor immunity., Elizabeth Sturgill, Annah S Rolig, Stefanie N Linch, Courtney Mick, Melissa Kasiewicz, Zhaoyu Sun, Peter G Traber, Harold Shlevin, and William L. Redmond

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Pralsetinib for patients with advanced or metastatic RET-altered thyroid cancer (ARROW): a multi-cohort, open-label, registrational, phase 1/2 study., Vivek Subbiah, Mimi I Hu, Lori J Wirth, Martin Schuler, Aaron S Mansfield, Giuseppe Curigliano, Marcia S Brose, Viola W Zhu, Sophie Leboulleux, Daniel W Bowles, Christina S Baik, Douglas Adkins, Bhumsuk Keam, Ignacio Matos, Elena Garralda, Justin F Gainor, Gilberto Lopes, Chia-Chi Lin, Yann Godbert, Debashis Sarker, Stephen G Miller, Corinne Clifford, Hui Zhang, Christopher D Turner, and Matthew H Taylor

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Developing an enhanced 7-color multiplex IHC protocol to dissect immune infiltration in human cancers., Zhaoyu Sun, Richard Nyberg, Yaping Wu, Brady Bernard, and William L. Redmond

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Intraoperative autologous transfusion and oncologic outcomes in liver transplantation for hepatocellular carcinoma: a propensity matched analysis., Thomas L Sutton, Jennifer Pasko, Gabrielle Kelly, Erin Maynard, Christopher Connelly, Susan Orloff, and C Kristian Enestvedt

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Assessment of Residual Cancer Burden and Event-Free Survival in Neoadjuvant Treatment for High-risk Breast Cancer: An Analysis of Data From the I-SPY2 Randomized Clinical Trial., W Fraser Symmans, Christina Yau, Yunn-Yi Chen, Ron Balassanian, Molly E Klein, Lajos Pusztai, Rita Nanda, Barbara A Parker, Brian Datnow, Gregor Krings, Shi Wei, Michael D Feldman, Xiuzhen Duan, Beiyun Chen, Husain Sattar, Laila Khazai, Jay C Zeck, Sharon Sams, Paulette Mhawech-Fauceglia, Mara Rendi, Sunati Sahoo, Idris Tolgay Ocal, Fang Fan, Lauren Grasso LeBeau, Tuyethoa Vinh, Megan L Troxell, A Jo Chien, Anne M Wallace, Andres Forero-Torres, Erin D Ellis, Kathy S Albain, Rashmi K Murthy, Judy C Boughey, Minetta C Liu, Barbara B Haley, Anthony D Elias, Amy S Clark, Kathleen Kemmer, Claudine Isaacs, Julie E Lang, Hyo S Han, Kirsten Edmiston, Rebecca K Viscusi, Donald W Northfelt, Qamar J Khan, Brian Leyland-Jones, Sara J Venters, Sonal Shad, Jeffrey B Matthews, Smita M Asare, Meredith Buxton, Adam L Asare, Hope S Rugo, Richard B Schwab, Teresa Helsten, Nola M Hylton, Laura van 't Veer, Jane Perlmutter, Angela M DeMichele, Douglas Yee, Donald A Berry, and Laura J Esserman

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Safety and Efficacy of Pembrolizumab in Combination with Acalabrutinib in Advanced Head and Neck Squamous Cell Carcinoma: Phase 2 Proof-of-Concept Study., Matthew H Taylor, Courtney B Betts, Lauren Maloney, Eric Nadler, Alain Algazi, Michael J Guarino, John Nemunaitis, Antonio Jimeno, Priti Patel, Veerendra Munugalavadla, Lin Tao, Douglas Adkins, Jerome H Goldschmidt, Ezra E W Cohen, and Lisa M Coussens

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Encorafenib and binimetinib with or without nivolumab in treating patients with metastatic radioiodine refractory BRAF V600 mutant thyroid cancer., Matthew H Taylor, Rom Leidner, Richard Bryan Bell, Bernard A Fox, and See full authors list in comments

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The LEAP program: lenvatinib plus pembrolizumab for the treatment of advanced solid tumors., Matthew H Taylor, Emmett V Schmidt, Corina Dutcus, Elaine M Pinheiro, Yasuhiro Funahashi, Gregory Lubiniecki, and Drew Rasco

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Correlation of Performance Status and Neutrophil-Lymphocyte Ratio With Efficacy in Radioiodine-Refractory Differentiated Thyroid Cancer Treated With Lenvatinib., Matthew H Taylor, Shunji Takahashi, Jaume Capdevila, Makoto Tahara, Sophie Leboulleux, Naomi Kiyota, Corina E Dutcus, Ran Xie, Bruce Robinson, Steven I Sherman, Mouhammed Amir Habra, Rossella Elisei, and Lori J Wirth

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Intratumoral Plasmid IL12 Expands CD8, Melinda L Telli, Hiroshi Nagata, Irene Wapnir, Chaitanya R Acharya, Kaitlin Zablotsky, Bernard A Fox, Carlo Bifulco, Shawn M. Jensen, Carmen Ballesteros-Merino, Mai Hope Le, Robert H Pierce, Erica Browning, Reneta Hermiz, Lauren Svenson, Donna Bannavong, Kim Jaffe, Jendy Sell, Kellie Malloy Foerter, David A Canton, Christopher G Twitty, Takuya Osada, H Kim Lyerly, and Erika J Crosby

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Can All of Us Reach that Peripheral Nodule: Potential Approaches to Electromagnetic Navigation CT-body Divergence., Jeffrey Thiboutot and Christopher R Gilbert

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Outcomes of Chronic Lymphocytic Leukemia and Richter Transformation Following Discontinuation of Non-Covalent Bruton's Tyrosine Kinase Inhibitors, Meghan C. Thompson, Neil Bailey, and See full list of authors in comments

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Addressing a New Challenge in Chronic Lymphocytic Leukemia: Outcomes of Therapies after Exposure to Both a Covalent Bruton's Tyrosine Kinase Inhibitor and Venetoclax, Meghan C. Thompson, John M Pagel, Neil Bailey, and See all authors in comments

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A Caenorhabditis elegans behavioral assay distinguishes early stage prostate cancer patient urine from controls, Morgan Thompson, Noemi Sarabia Feria, Ally Yoshioka, Eugene Tu, Fehmi Civitci, Suzanne Estes, and Josiah T Wagner

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Functional characterization of HIC, a P2Y1 agonist, as a p53 stabilizer for prostate cancer cell death induction., Hien Thi Thu Le, Akshaya Murugesan, Nuno R Candeias, Olli Yli-Harja, and Meenakshisundaram Kandhavelu

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Abemaciclib in Combination With Endocrine Therapy for Patients With Hormone Receptor-Positive, HER2-Negative Metastatic Breast Cancer: A Phase 1b Study., Sara M Tolaney, Muralidhar Beeram, J Thaddeus Beck, Alison Conlin, E Claire Dees, Shannon L Puhalla, Brent N Rexer, Howard A Burris, Komal Jhaveri, Teresa Helsten, Carlos Becerra, Kevin Kalinsky, Kathleen N Moore, Allison M Manuel, Andrew Lithio, Gregory L Price, Sonya C Chapman, Lacey M Litchfield, and Matthew P Goetz

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A Histopathologic Scoring System for Perineural Invasion Correlates With Adverse Outcomes in Patients With Cutaneous Squamous Cell Carcinoma., Mariam B Totonchy, Jennifer M McNiff, Kathleen C Suozzi, David J Leffell, and Sean R Christensen

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Assessment of Cell-Free microRNA by NGS Whole-Transcriptome Analysis in Cutaneous Melanoma Patients' Blood., Kevin Tran, Rebecca Gross, Negin Rahimzadeh, Shanthy Chenathukattil, Dave Hoon, and Matias A Bustos

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583 Exploring the potential of T cell acute lymphoblastic leukemia (T-ALL) for generating leukemia-specific T cell responses that can be therapeutically harnessed with immunotherapy, Todd Triplett, Andrew D Weinberg, and See full list of authors in comments

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Supportive Management of Patients with Advanced Pheochromocytomas and Paragangliomas Receiving PRRT., Erica S Tsang, Gayle Funk, Janet Leung, Grace Kalish, and Hagen F Kennecke

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18F-FDG-Avid Lymph Nodes After COVID-19 Vaccination on 18F-FDG PET/CT., Gary A Ulaner and Peter Giuliano

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Head-to-Head Evaluation of, Gary A Ulaner, Komal Jhaveri, Sarat Chandarlapaty, Vaios Hatzoglou, Christopher C Riedl, Jason S Lewis, and Audrey Mauguen

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Long-Term Outcomes of Intra-Arterial Chemotherapy for Progressive or Unresectable Pilocytic Astrocytomas: Case Studies., Kutluay Uluc, Dominic A Siler, Ricardo Lopez, Csanad Varallyay, Joao Prola Netto, Jenny Firkins, Cindy Lacy, Amy Huddleston, Prakash Ambady, and Edward A Neuwelt

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The impact of obesity on minimally invasive colorectal surgery: A report from the Surgical Care Outcomes Assessment Program collaborative., Kenley R Unruh, Amir Bastawrous, Jennifer A Kaplan, Ravi Moonka, Laila Rashidi, and Vlad V Simianu

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New clinical and biological insights from the international TARGIT-A randomised trial of targeted intraoperative radiotherapy during lumpectomy for breast cancer., Jayant S Vaidya, Max Bulsara, Michael Baum, Frederik Wenz, Samuele Massarut, Steffi Pigorsch, Michael Alvarado, Michael Douek, Christobel Saunders, Henrik Flyger, Wolfgang Eiermann, Chris Brew-Graves, Norman R Williams, Ingrid Potyka, Nicholas Roberts, Marcelle Bernstein, Douglas Brown, Elena Sperk, Siobhan Laws, Marc Sütterlin, Tammy Corica, Steinar Lundgren, Dennis Holmes, Lorenzo Vinante, Fernando Bozza, Montserrat Pazos, Magali Le Blanc-Onfroy, Günther Gruber, Wojciech Polkowski, Konstantin J Dedes, Marcus Niewald, Jens Blohmer, David McReady, Richard Hoefer, Pond Kelemen, Gloria Petralia, Mary Falzon, David Joseph, and Jeffrey S Tobias

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TARGIT-IORT during lumpectomy for breast cancer - better for patients than other PBI approaches., Jayant S Vaidya, Max Bulsara, Elena Sperk, Samuele Massarut, Michael Douek, Michael Alvarado, Steffi Pigorsch, Dennis R Holmes, Marcelle Bernstein, Christobel Saunders, Henrik Flyger, David Joseph, Frederik Wenz, and Jeffrey S Tobias

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Associations of Uncertainty With Psychological Health and Quality of Life in Older Adults With Advanced Cancer., Haydee C Verduzco-Aguirre, Dilip Babu, Supriya G Mohile, Javier Bautista, Huiwen Xu, Eva Culakova, Beverly Canin, Yingzi Zhang, Megan Wells, Ronald M Epstein, Paul Duberstein, Colin McHugh, William Dale, Alison Conlin, James Bearden, Jeffrey Berenberg, Mohamedtaki Tejani, and Kah Poh Loh

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CTNI-32. CASE SERIES OF BRAF INHIBITORS FOR THE TREATMENT OF BRAFV600E GLIOBLASTOMA, Naveed Wagle, Jose Carrillo, Akanksha Sharma, Minhdan Nguyen, Judy D Truong, Jared Chow, Evie Landa, Annie Heng, Jaya Mini Gill, Garni Barkhoudarian, Daniel F Kelly, and Santosh Kesari

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Genetic program activity delineates risk, relapse, and therapy responsiveness in multiple myeloma., Matthew A Wall, Serdar Turkarslan, Wei-Ju Wu, Samuel A Danziger, David J Reiss, Mike J Mason, Andrew P Dervan, Matthew W B Trotter, Douglas Bassett, Robert M Hershberg, Adrián López García de Lomana, Alexander V Ratushny, and Nitin S Baliga

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Circulating activated immune cells as a potential blood biomarkers of non-small cell lung cancer occurrence and progression., Yingyi Wang, Na Zhou, Rui Zhu, Xiaoyuan Li, Zhao Sun, Yang Gao, Wei Liu, Changting Meng, Yuping Ge, Chunmei Bai, Taisheng Li, and Hongsheng Liu

OX40 agonists enhance tumor Ag-specific T cell responses in cancer patients, Andrew D Weinberg

Enriching for Tumor-Reactive CD8 TIL with CD39/103 Markers: Implications for TIL Therapy, Andrew D. Weinberg

Adipocytes as Anticancer Drug Delivery Depot, D Wen, J Wang, and Z Gu

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Tumor Microenvironment, HLA Class I and APM Expression in HPV-Negative Oral Squamous Cell Carcinoma., Claudia Wickenhauser, Daniel Bethmann, Matthias Kappler, Alexander Walter Eckert, André Steven, Jürgen Bukur, Bernard Aloysius Fox, Jana Beer, and Barbara Seliger

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Ibrutinib Plus Venetoclax for First-Line Treatment of Chronic Lymphocytic Leukemia: Primary Analysis Results From the Minimal Residual Disease Cohort of the Randomized Phase II CAPTIVATE Study., William G Wierda, John N Allan, Tanya Siddiqi, Thomas J Kipps, Stephen Opat, Alessandra Tedeschi, Xavier C Badoux, Bryone J Kuss, Sharon Jackson, Carol Moreno, Ryan Jacobs, John M Pagel, Ian Flinn, Yvonne Pak, Cathy Zhou, Edith Szafer-Glusman, Joi Ninomoto, James P Dean, Danelle F James, Paolo Ghia, and Constantine S Tam

Distance between Indian health affiliated clinics and lung cancer screening sites suggest structural barriers in access to lung cancer screening in American Indian and Alaska Native communities in Washington State The American Thoracic Society San Diego, Californ, CL Wilshire

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Phase I/II study of nivolumab plus vorolanib in patients with thoracic malignancies: Interim efficacy of the SCLC and primary refractory NSCLC cohorts, and safety data across all cohorts., Selina K. Wong, Jennifer G. Whisenant, Rachel E Sanborn, and See list of authors in comments

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Exploration of Lipid Metabolism in Gastric Cancer: A Novel Prognostic Genes Expression Profile., Zhen Xiong, Yao Lin, Yan Yu, Xianghui Zhou, Jun Fan, Colin J Rog, Kailin Cai, Zheng Wang, Zhijie Chang, Guobin Wang, Kaixiong Tao, and Ming Cai

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Molecularly targeted treatment of recurrent anaplastic astrocytoma - a case report., Ashna Yalamanchi, Jaya Mini Gill, Judy Truong, Minhdan Nguyen, Jose Carrillo, Naveed Wagle, Akanksha Sharma, and Santosh Kesari

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Successful and durable response of primary CNS T-cell lymphoma to upfront temozolomide monotherapy., Meghna Yalamanchi, Akanksha Sharma, Minh Nguyen, Judy Truong, Jose A Carrillo, Naveed Wagle, Jaya M Gill, and Santosh Kesari

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Effects of radiation on tumor vasculature., Tomoko Yamazaki and Kristina H Young

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Hexokinase 2 discerns a novel circulating tumor cell population associated with poor prognosis in lung cancer patients., Liu Yang, Xiaowei Yan, Jie Chen, Qiong Zhan, Yingqi Hua, Shili Xu, Ziming Li, Zhuo Wang, Yu Dong, Dongqing Zuo, Min Xue, Yin Tang, Harvey R Herschman, Shun Lu, Qihui Shi, and Wei Wei

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Ganitumab and metformin plus standard neoadjuvant therapy in stage 2/3 breast cancer., Douglas Yee, Claudine Isaacs, Denise M Wolf, Christina Yau, Paul Haluska, Karthik V Giridhar, Andres Forero-Torres, A Jo Chien, Anne M Wallace, Lajos Pusztai, Kathy S Albain, Erin D Ellis, Heather Beckwith, Barbara B Haley, Anthony D Elias, Judy C Boughey, Kathleen Kemmer, Rachel L Yung, Paula R Pohlmann, Debu Tripathy, Amy S Clark, Hyo S Han, Rita Nanda, Qamar J Khan, Kristen K Edmiston, Emanuel F Petricoin, Erica Stringer-Reasor, Carla I Falkson, Melanie Majure, Rita A Mukhtar, Teresa L Helsten, Stacy L Moulder, Patricia A Robinson, Julia D Wulfkuhle, Lamorna Brown-Swigart, Meredith Buxton, Julia L Clennell, Melissa Paoloni, Ashish Sanil, Scott Berry, Smita M Asare, Amy Wilson, Gillian L Hirst, Ruby Singhrao, Adam L Asare, Jeffrey B Matthews, Nola M Hylton, Angela DeMichele, Michelle Melisko, Jane Perlmutter, Hope S Rugo, W Fraser Symmans, Laura J Van't Veer, Donald A Berry, and Laura J Esserman

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Adjuvant Radiation Field Extent and Sites of Failure in Node Positive Endometrioid Endometrial Cancer., D Yerramilli, Y H Chen, V Venkatachalam, G M Alban, D L Buscariollo, T Cheng, M King, J Pretz, A L Russo, and L J Lee

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Interleukin enhancer-binding factor 2 promotes cell proliferation and DNA damage response in metastatic melanoma., Xiaoqing Zhang, Matias A Bustos, Rebecca Gross, Romela Irene Ramos, Teh-Ling Takeshima, Gordon B Mills, Qiang Yu, and Dave S B Hoon

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Acetylated DNMT1 Downregulation and Related Regulatory Factors Influence Metastatic Melanoma Patients Survival., Xiaoqing Zhang, Matias A Bustos, Yoshiaki Shoji, Romela Irene Ramos, Yuuki Iida, Rebecca Gross, Teh-Ling Takeshima, and Dave Hoon

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Immune checkpoint inhibitor induced thyroid dysfunction is a frequent event post-treatment in NSCLC., Nanruoyi Zhou, Maria A Velez, Benjamin Bachrach, Jaklin Gukasyan, Charlene M Fares, Amy L Cummings, Jackson P Lind-Lebuffe, Wisdom O Akingbemi, Debory Y Li, Paige M Brodrick, Nawal M Yessuf, Sarah Rettinger, Tristan Grogan, Philippe Rochigneux, Jonathan W Goldman, Edward B Garon, and Aaron Lisberg

Submissions from 2020

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Pemigatinib for previously treated, locally advanced or metastatic cholangiocarcinoma: a multicentre, open-label, phase 2 study., Ghassan K Abou-Alfa, Vaibhav Sahai, Antoine Hollebecque, Gina Vaccaro, Davide Melisi, Raed Al-Rajabi, Andrew S Paulson, Mitesh J Borad, David Gallinson, Adrian G Murphy, Do-Youn Oh, Efrat Dotan, Daniel V Catenacci, Eric Van Cutsem, Tao Ji, Christine F Lihou, Huiling Zhen, Luis Féliz, and Arndt Vogel

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Epigenetic reprogramming at estrogen-receptor binding sites alters 3D chromatin landscape in endocrine-resistant breast cancer., Joanna Achinger-Kawecka, Fatima Valdes-Mora, Phuc-Loi Luu, Katherine A Giles, C Elizabeth Caldon, Wenjia Qu, Shalima Nair, Sebastian Soto, Warwick J Locke, Nicole S Yeo-Teh, Cathryn M Gould, Qian Du, Grady C Smith, Irene R Ramos, Kristine F Fernandez, Dave S B Hoon, Julia M W Gee, Clare Stirzaker, and Susan J Clark

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Cytotoxic T cell depletion with increasing epithelial abnormality in women with benign breast disease., Sabina Adhikary, Tanya L Hoskin, Melody L Stallings-Mann, Muhammad Arshad, Marlene H Frost, Stacey J Winham, Alvaro Peña, Delphine J Lee, Linda M Murphy, Michele Rakoff, Lori A Denison, Keith L Knutson, Derek C Radisky, Daniel W Visscher, and Amy C Degnim

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A generalizable data-driven multicellular model of pancreatic ductal adenocarcinoma., Boris Aguilar, David L Gibbs, David J Reiss, Mark McConnell, Samuel A Danziger, Andrew Dervan, Matthew Trotter, Douglas Bassett, Robert Hershberg, Alexander V Ratushny, and Ilya Shmulevich

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Preoperative imaging characteristics predict poor survival and inadequate resection for left-sided pancreatic adenocarcinoma: a multi-institutional analysis., Farzad Alemi, Zeljka Jutric, George R Marshall, Elliot J Scott, Jan Grendar, Alexandra M Roch, Lucio L Pereira, An-Lin Cheng, Paul D Hansen, Eugene P Ceppa, Horacio J Asbun, Susanne Warner, and Adnan A Alseidi

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Intratumoral delivery of tavokinogene telseplasmid yields systemic immune responses in metastatic melanoma patients., A Algazi, S Bhatia, S Agarwala, M Molina, K Lewis, M Faries, L Fong, L P Levine, M Franco, A Oglesby, C Ballesteros-Merino, C B Bifulco, B A Fox, D Bannavong, R Talia, E Browning, M H Le, R H Pierce, S Gargosky, K K Tsai, C Twitty, and A I Daud

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Phase II Trial of IL-12 Plasmid Transfection and PD-1 Blockade in Immunologically Quiescent Melanoma., Alain P Algazi, Christopher G Twitty, Katy K Tsai, Mai Le, Robert Pierce, Erica Browning, Reneta Hermiz, David A Canton, Donna Bannavong, Arielle Oglesby, Murray Francisco, Lawrence Fong, Mikael J Pittet, Sean P Arlauckas, Christopher Garris, Lauren P Levine, Carlo Bifulco, Carmen Ballesteros-Merino, Shailender Bhatia, Sharron Gargosky, Robert H I Andtbacka, Bernard A Fox, Michael D Rosenblum, and Adil I Daud

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Phase II Trial of IL-12 Plasmid Transfection and PD-1 Blockade in Immunologically Quiescent Melanoma., Alain P Algazi, Christopher G Twitty, Katy K Tsai, Mai Le, Robert Pierce, Erica Browning, Reneta Hermiz, David A Canton, Donna Bannavong, Arielle Oglesby, Murray Francisco, Lawrence Fong, Mikael J Pittet, Sean P Arlauckas, Christopher Garris, Lauren P Levine, Carlos Bifulco, Carmen Ballesteros-Merino, Shailender Bhatia, Sharron Gargosky, Robert H I Andtbacka, Bernard A Fox, Michael D Rosenblum, and Adil I Daud

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Estrogen and Progesterone Receptor Testing in Breast Cancer: American Society of Clinical Oncology/College of American Pathologists Guideline Update., Kimberly H Allison, M Elizabeth H Hammond, Mitchell Dowsett, Shannon E McKernin, Lisa A Carey, Patrick L Fitzgibbons, Daniel F Hayes, Sunil R Lakhani, Mariana Chavez-MacGregor, Jane Perlmutter, Charles M Perou, Meredith M Regan, David L Rimm, W Fraser Symmans, Emina E Torlakovic, Leticia Varella, Giuseppe Viale, Tracey F Weisberg, Lisa M McShane, and Antonio C Wolff