The Cancer Institute is a leader in cutting-edge treatments. Using a truly multidisciplinary approach, patients have access to advanced diagnostics, minimally invasive surgical interventions, and personalized genomic and immune-oncologic treatment options. Our team of cancer specialists – many of whom completed fellowships and specialty training at prestigious academic centers – offers comprehensive services for individuals with a cancer diagnosis.

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Submissions from 2017

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Second Primary Malignant Neoplasms and Survival in Adolescent and Young Adult Cancer Survivors., Theresa H M Keegan, Archie Bleyer, Aaron S Rosenberg, Qian Li, and Melanie Goldfarb

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In Reply: Endoscopic and Gravity-Assisted Resection of Medial Temporo-occipital Lesions Through a Supracerebellar Transtentorial Approach: Technical Notes With Case Illustrations., Daniel F Kelly and Garni Barkhoudarian

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Tumor-treating fields plus chemotherapy versus chemotherapy alone for glioblastoma at first recurrence: a post hoc analysis of the EF-14 trial., Santosh Kesari and Zvi Ram

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Brigatinib in Patients With Crizotinib-Refractory Anaplastic Lymphoma Kinase-Positive Non-Small-Cell Lung Cancer: A Randomized, Multicenter Phase II Trial., Dong-Wan Kim, Marcello Tiseo, Myung-Ju Ahn, Karen L Reckamp, Karin Holmskov Hansen, Sang-We Kim, Rudolf M Huber, Howard J. West, Harry J M Groen, Maximilian J Hochmair, Natasha B Leighl, Scott N Gettinger, Corey J Langer, Luis G Paz-Ares Rodríguez, Egbert F Smit, Edward S Kim, William Reichmann, Frank G Haluska, David Kerstein, and D Ross Camidge

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CCR4 is a determinant of melanoma brain metastasis., Anat Klein, Orit Sagi-Assif, Tsipi Meshel, Alona Telerman, Sivan Izraely, Shlomit Ben-Menachem, Jagadeesh Bayry, Diego M Marzese, Shuichi Ohe, Dave S B Hoon, Neta Erez, and Isaac P Witz

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A Comprehensive Patient-Derived Xenograft Collection Representing the Heterogeneity of Melanoma., Clemens Krepler, Katrin Sproesser, Patricia Brafford, Marilda Beqiri, Bradley Garman, Min Xiao, Batool Shannan, Andrea Watters, Michela Perego, Gao Zhang, Adina Vultur, Xiangfan Yin, Qin Liu, Ioannis N Anastopoulos, Bradley Wubbenhorst, Melissa A Wilson, Wei Xu, Giorgos Karakousis, Michael Feldman, Xiaowei Xu, Ravi Amaravadi, Tara C Gangadhar, David E Elder, Lauren E Haydu, Jennifer A Wargo, Michael A Davies, Yiling Lu, Gordon B Mills, Dennie T Frederick, Michal Barzily-Rokni, Keith T Flaherty, Dave S B Hoon, Michael Guarino, Joseph J Bennett, Randall W Ryan, Nicholas J Petrelli, Carol L Shields, Mizue Terai, Takami Sato, Andrew E Aplin, Alexander Roesch, David Darr, Steve Angus, Rakesh Kumar, Ensar Halilovic, Giordano Caponigro, Sebastien Jeay, Jens Wuerthner, Annette Walter, Matthias Ocker, Matthew B Boxer, Lynn Schuchter, Katherine L Nathanson, and Meenhard Herlyn

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Restriction Spectrum Imaging Improves Risk Stratification in Patients with Glioblastoma., A P Krishnan, R Karunamuni, K M Leyden, T M Seibert, R L Delfanti, J M Kuperman, H Bartsch, P Elbe, A Srikant, A M Dale, Santosh Kesari, D E Piccioni, J A Hattangadi-Gluth, N Farid, C R McDonald, and N S White

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Virtual Surgical Planning and Intraoperative Imaging in Management of Ballistic Facial and Mandibular Condylar Injuries., Philipp Kupfer, Allen Cheng, Ashish Patel, Melissa Amundson, Eric J Dierks, and R Bryan Bell

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Mutational Landscapes of Smoking-Related Cancers in Caucasians and African Americans: Precision Oncology Perspectives at Wake Forest Baptist Comprehensive Cancer Center., Ville Kytola, Umit Topaloglu, Lance D Miller, Rhonda L Bitting, Michael M Goodman, Ralph B D Agostino, Rodwige J Desnoyers, Carol Albright, George Yacoub, Shadi A Qasem, Barry DeYoung, Vesteinn Thorsson, Ilya Shmulevich, Meng Yang, Anastasia Shcherban, Matthew Pagni, Liang Liu, Matti Nykter, Kexin Chen, Gregory A Hawkins, Stefan C Grant, W Jeffrey Petty, Angela Tatiana Alistar, Edward A Levine, Edgar D Staren, Carl D Langefeld, Vincent Miller, Gaurav Singal, Robin M Petro, Mac Robinson, William Blackstock, Bayard L Powell, Lynne I Wagner, Kristie L Foley, Edward Abraham, Boris Pasche, and Wei Zhang

Mycobacterium bovis Bacillus Calmette-Guérin Alters Melanoma Microenvironment Favoring Antitumor T Cell Responses and Improving M2 Macrophage Function, Ricardo D Lardone, Alfred A Chan, Agnes F Lee, Leland J Foshag, Mark B Faries, Peter A Sieling, and Delphine J Lee

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Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade., Dung T Le, Jennifer N Durham, Kellie N Smith, Hao Wang, Bjarne R Bartlett, Laveet K Aulakh, Steve Lu, Holly Kemberling, Cara Wilt, Brandon S Luber, Fay Wong, Nilofer S Azad, Agnieszka A Rucki, Dan Laheru, Ross Donehower, Atif Zaheer, George A Fisher, Todd S Crocenzi, James J Lee, Tim F Greten, Austin G Duffy, Kristen K Ciombor, Aleksandra D Eyring, Bao H Lam, Andrew Joe, S Peter Kang, Matthias Holdhoff, Ludmila Danilova, Leslie Cope, Christian Meyer, Shibin Zhou, Richard M Goldberg, Deborah K Armstrong, Katherine M Bever, Amanda N Fader, Janis Taube, Franck Housseau, David Spetzler, Nianqing Xiao, Drew M Pardoll, Nickolas Papadopoulos, Kenneth W Kinzler, James R Eshleman, Bert Vogelstein, Robert A Anders, and Luis A Diaz

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The Importance of Standardization on Analyzing Circulating RNA., Inyoul Lee, David Baxter, Min Young Lee, Kelsey Scherler, and Kai Wang

Right internal jugular access as an alternative to femoral access for CardioMEMS implantation​, Rebecca Lewis, Lian Wang, Kateri Spinelli, Joshua Remick, Jeff Paulson, Jay Chappell, and Jacob Abraham

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Emerging Utility of Urinary Cell-free Nucleic Acid Biomarkers for Prostate, Bladder, and Renal Cancers., Selena Y Lin, Jennifer A Linehan, Timothy G Wilson, and Dave S B Hoon

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Modulation of Bax and mTOR for Cancer Therapeutics., Rui Li, Chunyong Ding, Jun Zhang, Maohua Xie, Dongkyoo Park, Ye Ding, Guo Chen, Guojing Zhang, Melissa Gilbert-Ross, Wei Zhou, Adam I Marcus, Shi-Yong Sun, Zhuo G Chen, Gabriel L Sica, Suresh S Ramalingam, Andrew T Magis, Haian Fu, Fadlo R Khuri, Walter J Curran, Taofeek K Owonikoko, Dong M Shin, Jia Zhou, and Xingming Deng

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Is tissue the issue?, Brian E Louie

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A Phase II Clinical Trial of an Aromatase Inhibitor for Postmenopausal Women with Lymphangioleiomyomatosis., Calvin Lu, Hye-Seung Lee, George P Pappas, Daniel F Dilling, Charles D Burger, Adrian Shifren, Srihari Veeraraghavan, Jeffrey T Chapman, Joseph Parambil, Stephen J Ruoss, Lisa R Young, Stephen R Hammes, Elizabeth J Kopras, Tammy Roads, Jeffrey P Krischer, and Francis X McCormack

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Mechanisms of radiotherapy-associated cognitive disability in patients with brain tumours., Milan T Makale, Carrie R McDonald, Jona A Hattangadi-Gluth, and Santosh Kesari

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The need for a network to establish and validate predictive biomarkers in cancer immunotherapy., Giuseppe V Masucci, Alessandra Cesano, Alexander Eggermont, Bernard A Fox, Ena Wang, Francesco M Marincola, Gennaro Ciliberto, Kevin Dobbin, Igor Puzanov, Janis Taube, Jennifer Wargo, Lisa H Butterfield, Lisa Villabona, Magdalena Thurin, Michael A Postow, Paul M Sondel, Sandra Demaria, Sanjiv Agarwala, and Paolo A Ascierto

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Neuroinflammatory and cognitive consequences of combined radiation and immunotherapy in a novel preclinical model., Gwendolyn J McGinnis, David Friedman, Kristina H Young, Eileen Ruth S Torres, Charles R Thomas, Michael J Gough, and Jacob Raber

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Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes., James D McKay, Rayjean J Hung, Younghun Han, Xuchen Zong, Robert Carreras-Torres, David C Christiani, Neil E Caporaso, Mattias Johansson, Xiangjun Xiao, Yafang Li, Jinyoung Byun, Alison Dunning, Karen A Pooley, David C Qian, Xuemei Ji, Geoffrey Liu, Maria N Timofeeva, Stig E Bojesen, Xifeng Wu, Loic Le Marchand, Demetrios Albanes, Heike Bickeböller, Melinda C Aldrich, William S Bush, Adonina Tardon, Gad Rennert, M Dawn Teare, John K Field, Lambertus A Kiemeney, Philip Lazarus, Aage Haugen, Stephen Lam, Matthew B Schabath, Angeline S Andrew, Hongbing Shen, Yun-Chul Hong, Jian-Min Yuan, Pier Alberto Bertazzi, Angela C Pesatori, Yuanqing Ye, Nancy Diao, Li Su, Ruyang Zhang, Yonathan Brhane, Natasha Leighl, Jakob S Johansen, Anders Mellemgaard, Walid Saliba, Christopher A Haiman, Lynne R Wilkens, Ana Fernandez-Somoano, Guillermo Fernandez-Tardon, Henricus F M van der Heijden, Jin Hee Kim, Juncheng Dai, Zhibin Hu, Michael P A Davies, Michael W Marcus, Hans Brunnström, Jonas Manjer, Olle Melander, David C Muller, Kim Overvad, Antonia Trichopoulou, Rosario Tumino, Jennifer A Doherty, Matt P Barnett, Chu Chen, Gary E Goodman, Angela Cox, Fiona Taylor, Penella Woll, Irene Brüske, H-Erich Wichmann, Judith Manz, Thomas R Muley, Angela Risch, Albert Rosenberger, Kjell Grankvist, Mikael Johansson, Frances A Shepherd, Ming-Sound Tsao, Susanne M Arnold, Eric B Haura, Ciprian Bolca, Ivana Holcatova, Vladimir Janout, Milica Kontic, Jolanta Lissowska, Anush Mukeria, Simona Ognjanovic, Tadeusz M Orlowski, Ghislaine Scelo, Beata Swiatkowska, David Zaridze, Per Bakke, Vidar Skaug, Shanbeh Zienolddiny, Eric J Duell, Lesley M Butler, Woon-Puay Koh, Yu-Tang Gao, Richard S Houlston, John McLaughlin, Victoria L Stevens, Philippe Joubert, Maxime Lamontagne, David C Nickle, Ma'en Obeidat, Wim Timens, Bin Zhu, Lei Song, Linda Kachuri, María Soler Artigas, Martin D Tobin, Louise V Wain, Thorunn Rafnar, Thorgeir E Thorgeirsson, Gunnar W Reginsson, Kari Stefansson, Dana B Hancock, Laura J Bierut, Margaret R Spitz, Nathan C Gaddis, Sharon M Lutz, Fangyi Gu, Eric O Johnson, Ahsan Kamal, Claudio Pikielny, Dakai Zhu, Sara Lindströem, Xia Jiang, Rachel F Tyndale, Georgia Chenevix-Trench, Jonathan Beesley, Yohan Bossé, Stephen Chanock, Paul Brennan, Maria Teresa Landi, and Christopher I Amos

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Timing of PD-1 Blockade Is Critical to Effective Combination Immunotherapy with Anti-OX40., David J Messenheimer, Shawn M. Jensen, Michael E Afentoulis, Keith W Wegman, Zipei Feng, David J Friedman, Michael J. Gough, Walter Urba, and Bernard A Fox

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Curcumin and Turmeric Modulate the Tumor-Promoting Effects of Iron In Vitro., Donald J Messner, Todd Robinson, and Kris V Kowdley

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Effect of Infla-Kine supplementation on the gene expression of inflammatory markers in peripheral mononuclear cells and on C-reactive protein in blood., Nina A Mikirova, Santosh Kesari, Thomas E Ichim, and Neil H Riordan

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Pack-Year Cigarette Smoking History for Determination of Lung Cancer Screening Eligibility. Comparison of the Electronic Medical Record versus a Shared Decision-making Conversation., Hannah E Modin, Joelle T Fathi, Christopher R Gilbert, Candice L Wilshire, Andrew K Wilson, Ralph W Aye, Alexander S Farivar, Brian E Louie, Eric Vallières, and Jed A Gorden

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The Effect of Superparamagnetic Iron Oxide Nanoparticle Surface Charge on Antigen Cross-Presentation., Yongbin Mou, Yun Xing, Hongyan Ren, Zhihua Cui, Yu Zhang, Guangjie Yu, Walter J Urba, Qingang Hu, and Hongming Hu

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LINE-1 hypomethylation status of circulating cell-free DNA in plasma as a biomarker for colorectal cancer., Yuzo Nagai, Eiji Sunami, Yoko Yamamoto, Keisuke Hata, Satoshi Okada, Koji Murono, Koji Yasuda, Kensuke Otani, Takeshi Nishikawa, Toshiaki Tanaka, Tomomichi Kiyomatsu, Kazushige Kawai, Hiroaki Nozawa, Soichiro Ishihara, Dave S B Hoon, and Toshiaki Watanabe

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SMARCB1 is required for widespread BAF complex-mediated activation of enhancers and bivalent promoters., Robert T Nakayama, John L Pulice, Alfredo M Valencia, Matthew J McBride, Zachary M McKenzie, Mark A Gillespie, Wai Lim Ku, Mingxiang Teng, Kairong Cui, Robert T Williams, Seth H Cassel, He Qing, Christian J Widmer, George D Demetri, Rafael A Irizarry, Keji Zhao, Jeffrey A Ranish, and Cigall Kadoch

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Sex-specific associations of maternal birthweight with offspring birthweight in the Omega study., Collette N Ncube, Amelia R Gavin, Michelle A Williams, Chunfang Qiu, Tanya K Sorensen, and Daniel A Enquobahrie

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Impact of Time Between Diagnosis and SLNB on Outcomes in Cutaneous Melanoma., Daniel W Nelson, Stacey Stern, David E Elashoff, Robert Elashoff, John F Thompson, Nicola Mozzillo, Omgo E Nieweg, Harald J Hoekstra, Alistair J Cochran, and Mark B Faries

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Toxoplasma Modulates Signature Pathways of Human Epilepsy, Neurodegeneration & Cancer., Huân M Ngô, Ying Zhou, Hernan Lorenzi, Kai Wang, Taek-Kyun Kim, Yong Zhou, Kamal El Bissati, Ernest Mui, Laura Fraczek, Seesandra V Rajagopala, Craig W Roberts, Fiona L Henriquez, Alexandre Montpetit, Jenefer M Blackwell, Sarra E Jamieson, Kelsey Wheeler, Ian J Begeman, Carlos Naranjo-Galvis, Ney Alliey-Rodriguez, Roderick G Davis, Liliana Soroceanu, Charles Cobbs, Dennis A Steindler, Kenneth Boyer, A Gwendolyn Noble, Charles N Swisher, Peter T Heydemann, Peter Rabiah, Shawn Withers, Patricia Soteropoulos, Leroy Hood, and Rima McLeod

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The diagnostic challenge of low-grade ductal carcinoma in situ., Tracy Onega, Donald L Weaver, Paul D Frederick, Kimberly H Allison, Anna N A Tosteson, Patricia A Carney, Berta M Geller, Gary M Longton, Heidi D Nelson, Natalia V Oster, Margaret S Pepe, and Joann G Elmore

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RRx-001: a systemically non-toxic M2-to-M1 macrophage stimulating and prosensitizing agent in Phase II clinical trials., Bryan Oronsky, Ramasamy Paulmurugan, Kira Foygel, Jan Scicinski, Susan J Knox, Donna Peehl, Hongjuan Zhao, Shoucheng Ning, Pedro Cabrales, Thomas A Summers, Tony R Reid, William L Fitch, Michelle M Kim, Jane B Trepel, Min-Jung Lee, Santosh Kesari, Nacer D Abrouk, Regina M Day, Arnold Oronsky, Carolyn M Ray, and Corey A Carter

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The prognostic importance of scalp location in primary head and neck melanoma., Junko Ozao-Choy, Daniel W Nelson, Jason Hiles, Stacey L Stern, Jeong Lim Yoon, Myung Shin Sim, and Mark Faries

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Emergence of EGFR G724S mutation in EGFR-mutant lung adenocarcinoma post progression on osimertinib., A Oztan, S Fischer, A B Schrock, R L Erlich, C M Lovly, P J Stephens, J S Ross, V Miller, S M Ali, S-H I Ou, and L E Raez

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A Richter transformation PD-1 block party., John M Pagel

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Contemporary minimally invasive surgery for adrenal masses: it's not all about (pure) laparoscopy., Nicola Pavan, Ithaar Derweesh, Jens Rassweiler, Benjamin Challacombe, Homayoun Zargar, James Porter, Evangelos Liatsikos, Jihad Kaouk, Francesco Porpiglia, and Riccardo Autorino

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Robot assisted lymphadenectomy in urology: pelvic, retroperitoneal and inguinal., Giovannalberto Pini, Surena F Matin, Nazareno Suardi, Mihir Desai, Inderbir Gill, James Porter, Robert J Stein, Rene Sotelo, Franco Gaboardi, and Francesco Porpiglia

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Differentiated State of Initiating Tumor Cells Is Key to Distinctive Immune Responses Seen in H-Ras, Michael A Podolsky, Jacob T Bailey, Andrew J Gunderson, Carrie J Oakes, Kyle Breech, and Adam B Glick

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Ion channel expression patterns in glioblastoma stem cells with functional and therapeutic implications for malignancy., Julia Pollak, Karan G Rai, Cory C Funk, Sonali Arora, Eunjee Lee, Jun Zhu, Nathan D Price, Patrick J Paddison, Jan-Marino Ramirez, and Robert C Rostomily

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Multiscale mutation clustering algorithm identifies pan-cancer mutational clusters associated with pathway-level changes in gene expression., William Poole, Kalle Leinonen, Ilya Shmulevich, Theo A Knijnenburg, and Brady Bernard

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The Role of Lymphadenectomy for Renal Cell Carcinoma: Are we any Closer to an Answer?, James R Porter

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Anomalies in the dominant sarcoidosis paradigm justify its displacement., Jerome M Reich

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In Memoriam: Laurence E. Karp (1939-2016)., Robert Resta

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The ISB Cancer Genomics Cloud: A Flexible Cloud-Based Platform for Cancer Genomics Research., Sheila M Reynolds, Michael Miller, Phyliss Lee, Kalle Leinonen, Suzanne M Paquette, Zack Rodebaugh, Abigail Hahn, David L Gibbs, Joseph Slagel, William J Longabaugh, Varsha Dhankani, Madelyn Reyes, Todd Pihl, Mark Backus, Matthew Bookman, Nicole Deflaux, Jonathan Bingham, David Pot, and Ilya Shmulevich

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Tumor and Microenvironment Evolution during Immunotherapy with Nivolumab., Nadeem Riaz, Jonathan J Havel, Vladimir Makarov, Alexis Desrichard, Walter Urba, Jennifer S Sims, F Stephen Hodi, Salvador Martín-Algarra, Rajarsi Mandal, William H Sharfman, Shailender Bhatia, Wen-Jen Hwu, Thomas F Gajewski, Craig L Slingluff, Diego Chowell, Sviatoslav M Kendall, Han Chang, Rachna Shah, Fengshen Kuo, Luc G T Morris, John-William Sidhom, Jonathan P Schneck, Christine E Horak, Nils Weinhold, and Timothy A Chan

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Breast Malignancies in Children: Presentation, Management, and Survival., Morgan K Richards, Adam B Goldin, Elizabeth A Beierle, John J Doski, Melanie Goldfarb, Monica Langer, Jed G Nuchtern, Sanjeev Vasudevan, Kenneth W Gow, and Sara H Javid

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The association between nephroblastoma-specific outcomes and high versus low volume treatment centers., Morgan K Richards, Adam B Goldin, Alexandra Savinkina, John Doski, Melanie Goldfarb, Jed Nuchtern, Monica Langer, Elizabeth A Beierle, Sanjeev Vasudevan, Kenneth W Gow, and Mehul V Raval

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Integrative Analysis Identifies Four Molecular and Clinical Subsets in Uveal Melanoma., A Gordon Robertson, Juliann Shih, Christina Yau, Ewan A Gibb, Junna Oba, Karen L Mungall, Julian M Hess, Vladislav Uzunangelov, Vonn Walter, Ludmila Danilova, Tara M Lichtenberg, Melanie Kucherlapati, Patrick K Kimes, Ming Tang, Alexander Penson, Ozgun Babur, Rehan Akbani, Christopher A Bristow, Katherine A Hoadley, Lisa Iype, Matthew T Chang, Andrew D Cherniack, Christopher Benz, Gordon B Mills, Roel G W Verhaak, Klaus G Griewank, Ina Felau, Jean C Zenklusen, Jeffrey E Gershenwald, Lynn Schoenfield, Alexander J Lazar, Mohamed H Abdel-Rahman, Sergio Roman-Roman, Marc-Henri Stern, Colleen M Cebulla, Michelle D Williams, Martine J Jager, Sarah E Coupland, Bita Esmaeli, Cyriac Kandoth, and Scott E Woodman

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A community affair in the tumor microenvironment., Jeffrey J Rodvold, Santosh Kesari, and Maurizio Zanetti

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miR-144 attenuates the host response to influenza virus by targeting the TRAF6-IRF7 signaling axis., Carrie M Rosenberger, Rebecca L Podyminogin, Alan H Diercks, Piper M Treuting, Jacques J Peschon, David Rodriguez, Madhumati Gundapuneni, Mitchell J Weiss, and Alan Aderem

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The RhoJ-BAD signaling network: An Achilles' heel for BRAF mutant melanomas., Rolando Ruiz, Sohail Jahid, Melissa Harris, Diego M Marzese, Francisco Espitia, Priya Vasudeva, Chi-Fen Chen, Sebastien de Feraudy, Jie Wu, Daniel L Gillen, Tatiana B Krasieva, Bruce J Tromberg, William J Pavan, Dave S B Hoon, and Anand K Ganesan

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Surgical implications and variability in the use of the flat epithelial atypia diagnosis on breast biopsy specimens., Laura S Samples, Mara H Rendi, Paul D Frederick, Kimberly H Allison, Heidi D Nelson, Thomas R Morgan, Donald L Weaver, and Joann G Elmore

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A pilot study of an autologous tumor-derived autophagosome vaccine with docetaxel in patients with stage IV non-small cell lung cancer., Rachel E Sanborn, Helen J Ross, Sandra Aung, Anupama Acheson, Tarsem Moudgil, Sachin Puri, Traci Hilton, Brenda Fisher, Todd Coffey, Christopher Paustian, Michael Neuberger, Edwin Walker, Hong-Ming Hu, Walter Urba, and Bernard A Fox

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Cognitive dysfunction in patients with brain metastases: influences on caregiver resilience and coping., Marlon Garzo Saria, Natasia Courchesne, Lorraine Evangelista, Joshua Carter, Daniel A MacManus, Mary Kay Gorman, Adeline M Nyamathi, Linda R Phillips, David Piccioni, Santosh Kesari, and Sally Maliski

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The Hidden Morbidity of Cancer: Burden in Caregivers of Patients with Brain Metastases., Marlon Garzo Saria, Adeline Nyamathi, Linda R Phillips, Annette L Stanton, Lorraine Evangelista, Santosh Kesari, and Sally Maliski

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Persuasive Interventions for Controversial Cancer Screening Recommendations: Testing a Novel Approach to Help Patients Make Evidence-Based Decisions., Barry Saver, Kathleen M Mazor, Roger Luckmann, Sarah L Cutrona, Marcela Hayes, Tatyana Gorodetsky, Nancy Esparza, and Gonzalo Bacigalupe

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Differential phenotypes of memory CD4 and CD8 T cells in the spleen and peripheral tissues following immunostimulatory therapy., Gail D Sckisel, Annie Mirsoian, Christine M Minnar, Marka R Crittenden, Brendan Curti, Jane Q Chen, Bruce R Blazar, Alexander D Borowsky, Arta M Monjazeb, and William J Murphy

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Margin Analysis: Squamous Cell Carcinoma of the Oropharynx., Felix W Sim, Hong D Xiao, and R Bryan Bell

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Hypothermic Cooling Measured by Thermal Magnetic Resonance Imaging; Feasibility and Implications for Virtual Imaging in the Urogenital Pelvis., Douglas Skarecky, Hon Yu, Jennifer Linehan, Blanca Morales, Min-Ying Su, Peter Fwu, and Thomas Ahlering

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Cellular immunotherapy of cancer: an overview and future directions., Ziqi Tao, Shuang Li, Thomas E Ichim, Junbao Yang, Neil Riordan, Venkata Yenugonda, Ivan Babic, and Santosh Kesari

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Outcomes of octogenarians undergoing gastrectomy performed for malignancy., Annabelle Teng, Geoffrey Bellini, Erica Pettke, Michael Passeri, David Y Lee, Keith Rose, Anton J Bilchik, and Fadi Attiyeh

nab-paclitaxel/carboplatin induction in squamous NSCLC: longitudinal quality of life while on chemotherapy, Michael Thomas, David R Spigel, Robert M Jotte, Michael McCleod, Mark A Socinski, Ray D Page, Laurent Gressot, Jeanna Knoble, Oscar Juan, Daniel Morgensztern, Dolores Isla, Edward S Kim, Howard West, Amy Ko, Teng Jin Ong, Nataliya Trunova, and Cesare Gridelli

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The influence of tumor regression, solar elastosis, and patient age on pathologists' interpretation of melanocytic skin lesions., Linda Titus, Raymond L Barnhill, Jason P Lott, Michael W Piepkorn, David E Elder, Paul D Frederick, Heidi D Nelson, Patricia A Carney, Stevan R Knezevich, Martin A Weinstock, and Joann G Elmore

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A Milestone for CAR T Cells., Eric Tran, Dan L Longo, and Walter Urba

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Unresectable hepatoblastoma: current perspectives., Angela D Trobaugh-Lotrario, Rebecka L Meyers, Allison F O'Neill, and James H Feusner

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Early stage small cell lung cancer: very rare, but a surgical disease!, Eric Vallières

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Neurological improvement of perineural and leptomeningeal spread of squamous cell carcinoma treated with intrathecal chemotherapy and systemic EGFR inhibition., Vincent Alexander van Vugt, Marlon Garzo Saria, Andres Javier, Navin Kesari, Tiffany Turpin, and Santosh Kesari

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Proceedings of the first international state-of-the-art conference on minimally-invasive pancreatic resection (MIPR)., Charles M Vollmer, Horacio J Asbun, Jeffrey Barkun, Marc G Besselink, Ugo Boggi, Kevin C P Conlon, Ho-Seong Han, Paul D Hansen, Michael L Kendrick, Andre L Montagnini, C Palanivelu, Bård I Røsok, Shailesh V Shrikhande, Go Wakabayashi, Herbert J Zeh, and David A Kooby

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Induction and characterization of anti-tumor endothelium immunity elicited by ValloVax therapeutic cancer vaccine., Samuel C Wagner, Thomas E Ichim, Vladimir Bogin, Wei-Ping Min, Francisco Silva, Amit N Patel, and Santosh Kesari

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A phase Ib/II study of cabozantinib (XL184) with or without erlotinib in patients with non-small cell lung cancer., Heather A Wakelee, Scott Gettinger, Jeffrey Engelman, Pasi A Jänne, Howard J. West, Deepa S Subramaniam, Joseph Leach, Michael Wax, Yifah Yaron, Dale R Miles, and Primo N Lara

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P-REX1 amplification promotes progression of cutaneous melanoma via the PAK1/P38/MMP-2 pathway., Jinhua Wang, Hajime Hirose, Guanhua Du, Kelly Chong, Eiji Kiyohara, Isaac P Witz, and Dave S B Hoon

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FOXC1 is associated with estrogen receptor alpha and affects sensitivity of tamoxifen treatment in breast cancer., Jinhua Wang, Yali Xu, Li Li, Lin Wang, Ru Yao, Qiang Sun, and Guanhua Du

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Meta-analysis of five genome-wide association studies identifies multiple new loci associated with testicular germ cell tumor., Zhaoming Wang, Katherine A McGlynn, Ewa Rajpert-De Meyts, D Timothy Bishop, Charles C Chung, Marlene D Dalgaard, Mark H Greene, Ramneek Gupta, Tom Grotmol, Trine B Haugen, Robert Karlsson, Kevin Litchfield, Nandita Mitra, Kasper Nielsen, Louise C Pyle, Stephen M Schwartz, Vésteinn Thorsson, Saran Vardhanabhuti, Fredrik Wiklund, Clare Turnbull, Stephen J Chanock, Peter A Kanetsky, and Katherine L Nathanson

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Physician Aid in Dying: Caught Between the Extremes., Jeffery Ward

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Chemotherapy-Induced Hair Loss (Alopecia)., Howard J. West

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Insights into Local Tumor Microenvironment Immune Factors Associated with Regression of Cutaneous Melanoma Metastases by, Junbao Yang, Maris S Jones, Romela Irene Ramos, Alfred A Chan, Agnes F Lee, Leland J Foshag, Peter A Sieling, Mark Faries, and Delphine J Lee

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A novel small molecule inhibitor of p32 mitochondrial protein overexpressed in glioma., Venkata Yenugonda, Natsuko Nomura, Valentina Kouznetsova, Igor Tsigelny, Valentina Fogal, Elmar Nurmemmedov, Santosh Kesari, and Ivan Babic

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Beyond cancer genes: colorectal cancer as robust intrinsic states formed by molecular interactions., Ruoshi Yuan, Suzhan Zhang, Jiekai Yu, Yanqin Huang, Demin Lu, Runtan Cheng, Sui Huang, Ping Ao, Shu Zheng, Leroy Hood, and Xiaomei Zhu

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A Phase I, Dose Escalation Study of Oral ASP8273 in Patients with Non-small Cell Lung Cancers with Epidermal Growth Factor Receptor Mutations., Helena A Yu, Alexander Spira, Leora Horn, Jared Weiss, Howard J. West, Giuseppe Giaccone, Tracey Evans, Ronan J Kelly, Bhardwaj Desai, Andrew Krivoshik, Diarmuid Moran, Srinivasu Poondru, Fei Jie, Kouji Aoyama, Anne Keating, and Geoffrey R Oxnard

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Early mutation bursts in colorectal tumors., Junsong Zhao, Matthew P Salomon, Darryl Shibata, Christina Curtis, Kimberly Siegmund, and Paul Marjoram

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Susceptibility loci of CNOT6 in the general mRNA degradation pathway and lung cancer risk-A re-analysis of eight GWASs., Fei Zhou, Yanru Wang, Hongliang Liu, Neal Ready, Younghun Han, Rayjean J Hung, Yonathan Brhane, John McLaughlin, Paul Brennan, Heike Bickeböller, Albert Rosenberger, Richard S Houlston, Neil Caporaso, Maria Teresa Landi, Irene Brüske, Angela Risch, Yuanqing Ye, Xifeng Wu, David C Christiani, Gary Goodman, Chu Chen, Christopher I Amos, and Qingyi Wei

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Extracting Intercellular Signaling Network of Cancer Tissues using Ligand-Receptor Expression Patterns from Whole-tumor and Single-cell Transcriptomes., Joseph X Zhou, Roberto Taramelli, Edoardo Pedrini, Theo Knijnenburg, and Sui Huang

Submissions from 2016

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Donald L. Morton, MD.... A Legendary Surgical Oncologist and Consummate Investigator., Charles M Balch and Dave S B Hoon

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Characterization of the microbiome of nipple aspirate fluid of breast cancer survivors., Alfred A Chan, Mina Bashir, Magali N Rivas, Karen Duvall, Peter A Sieling, Thomas R Pieber, Parag A Vaishampayan, Susan M Love, and Delphine J Lee

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Earle A. Chiles Research Institute 2015 Year In Review, Earle A. Chiles Research Institute

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Donald L. Morton, MD 1934-2014., Dave S B Hoon

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Preface: The Living Legacy of Donald L. Morton., Dave S B Hoon

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Logic models to predict continuous outputs based on binary inputs with an application to personalized cancer therapy., Theo A Knijnenburg, Gunnar W Klau, Francesco Iorio, Mathew J Garnett, Ultan McDermott, Ilya Shmulevich, and Lodewyk F A Wessels

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Navigating your career path in pediatric hematology/oncology: On and off the beaten track., Patrick A Zweidler-McKay, Mary-Jane Staba Hogan, Rima Jubran, Vandy Black, Jacqueline Casillas, James Harper, Suman Malempati, Judith Margolin, Judy Felgenhauer, Kathleen M Sakamoto, Janet Franklin, Mona Shah, Nita Seibel, George Buchanan, Sarah R Vaiselbuh, Caroline Hastings, Joanne Hilden, and Linda C Stork

Submissions from 2015

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Allogeneic autophagosome-enriched composition for the treatment of disease, Traci Hilton, Sandra Aung, Rieneke van de Ven, Christopher Paustian, Tarsem Moudgil, Christopher Dubay, Christopher Twitty, Hong-Ming Hu, and Bernard A Fox

Submissions from 2014

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Cancer treatment and monitoring methods using OX40 agonists, Brendan Curti, Magdalena Kovacsovics-Bankowski, Ed Walker, Josh Walker, and Andy Weinberg

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Ubiquitinylated proteins, Christopher Twitty, Erik LeShane, Bernard A Fox, Hong-Ming Hu, and Guangjie Yu

Submissions from 2013

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Allogeneic autophagosome-enriched composition for the treatment of disease, Traci Hilton, Sandra Aung, Rieneke van de Ven, Christopher Paustian, Tarsem Moudgil, Christopher Dubay, Christopher Twitty, Hong-Ming Hu, and Bernard A. Fox

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Methods for diagnosis, prognosis and treatment of primary and metastatic basal-like breast cancer and other cancer types, Partha S. Ray, Sanjay Bagaria, Xiaojiang Cui, and Jinhua Wang

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Method for enhancing specific immunotherapies in cancer treatment, Peter G. Traber, William L. Redmond, Eliezer Zomer, Anatole Klyosov, and Stefanie N. Linch

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Molecular malignancy in melanocytic lesions, Hui Wang, Christopher Roberts, Krishna Maddula, Zhenquiang Lu, Tom Vasicek, BJ Kerns, Bruce E. Seligmann, and Dave S B Hoon

Submissions from 2012

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Utility of B-RAF DNA mutation in diagnosis and treatment of cancer, Dave S B Hoon

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Long noncoding RNA (lncRNA) as a biomarker and therapeutic marker in cancer, Dave S B Hoon and Laurent Lessard

Submissions from 2011

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Treatment of cancer and compositions, Richard Essner