The Cancer Institute is a leader in cutting-edge treatments. Using a truly multidisciplinary approach, patients have access to advanced diagnostics, minimally invasive surgical interventions, and personalized genomic and immune-oncologic treatment options. Our team of cancer specialists – many of whom completed fellowships and specialty training at prestigious academic centers – offers comprehensive services for individuals with a cancer diagnosis.

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Submissions from 2021

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Minimal Residual Disease in Myeloma: Application for Clinical Care and New Drug Registration., Kenneth C Anderson, Daniel Auclair, Stacey J Adam, Amit Agarwal, Melissa Anderson, Herve Avet-Loiseau, Mark Bustoros, Jessica Chapman, Dana E Connors, Ajeeta Dash, Alessandra Di Bacco, Ling Du, Thierry Facon, Juan Flores-Montero, Francesca Gay, Irene M Ghobrial, Nicole J Gormley, Ira Gupta, Howard Higley, Jens Hillengass, Bindu Kanapuru, Dickran Kazandjian, Gary J Kelloff, Ilan R Kirsch, Brandon E Kremer, Ola Landgren, Elizabeth D Lightbody, Oliver C Lomas, Sagar Lonial, Maria Victoria Mateos, Rocio Montes de Oca, Lata Mukundan, Nikhil C Munshi, Elizabeth K O'Donnell, Alberto Orfao, Bruno Paiva, Reshma Patel, Trevor J Pugh, Karthik Ramasamy, Jill Ray, Mikhail Roshal, Jeremy A Ross, Caroline C Sigman, Katie L Thoren, Suzanne Trudel, Gary A Ulaner, Nancy Valente, Brendan M Weiss, Elena Zamagni, and Shaji K Kumar

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Persistent N2 Following Induction Is Not a Contraindication to Surgery for Lung Cancer., Weston G Andrews, Brian Louie, Massimo Castiglioni, Ankit Dhamija, Alexander S Farivar, Joshua Chansky, Peter T White, Ralph W Aye, Eric Vallieres, and Adam J Bograd

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Implications of Adverse Biological Factors and Management of Solitary Fibrous Tumors of the Pleura., Weston G Andrews and Eric Vallières

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Clinical Responses of Oncolytic Coxsackievirus A21 (V937) in Patients With Unresectable Melanoma., Robert H I Andtbacka, Brendan Curti, Gregory A Daniels, Sigrun Hallmeyer, Eric D Whitman, Jose Lutzky, Lynn E Spitler, Karl Zhou, Praveen K Bommareddy, Mark Grose, Meihua Wang, Cai Wu, and Howard L Kaufman

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Utilizing an interim futility analysis of the OVAL study (VB-111-701/GOG 3018) for potential reduction of risk: A phase III, double blind, randomized controlled trial of ofranergene obadenovec (VB-111) and weekly paclitaxel in patients with platinum resistant ovarian cancer., Rebecca C Arend, Bradley J Monk, Thomas J Herzog, Kathleen N Moore, Ronnie Shapira-Frommer, Jonathan A Ledermann, Krishnansu S Tewari, Angeles Alvarez Secord, Tamar Rachmilewitz Minei, Laurence S Freedman, Austin Miller, Shifra Fain Shmueli, Michal Lavi, and Richard T Penson

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iNetModels 2.0: an interactive visualization and database of multi-omics data., Muhammad Arif, Cheng Zhang, Xiangyu Li, Cem Güngör, Buğra Çakmak, Metin Arslantürk, Abdellah Tebani, Berkay Özcan, Oğuzhan Subaş, Wenyu Zhou, Brian Piening, Hasan Turkez, Linn Fagerberg, Nathan Price, Leroy Hood, Michael Snyder, Jens Nielsen, Mathias Uhlen, and Adil Mardinoglu

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Perspectives in immunotherapy: meeting report from the immunotherapy bridge (December 2nd-3rd, 2020, Italy)., Paolo A Ascierto, Carlo Bifulco, Fortunato Ciardiello, Sandra Demaria, Leisha A Emens, Robert Ferris, Silvia C Formenti, Jerome Galon, Samir N Khleif, Tomas Kirchhoff, Jennifer McQuade, Kunle Odunsi, Akash Patnaik, Chrystal M Paulos, Janis M Taube, John Timmerman, Bernard A Fox, Patrick Hwu, and Igor Puzanov

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Perspectives in Melanoma: meeting report from the Melanoma Bridge (December 3rd-5th, 2020, Italy)., Paolo A Ascierto, Christian Blank, Reinhard Dummer, Marc S Ernstoff, Soldano Ferrone, Bernard A Fox, Thomas F Gajewski, Claus Garbe, Patrick Hwu, Pawel Kalinski, Michelle Krogsgaard, Roger S Lo, Jason J Luke, Bart Neyns, Michael A Postow, Sergio A Quezada, Michele W L Teng, Giorgio Trinchieri, Alessandro Testori, Corrado Caracò, Iman Osman, Igor Puzanov, and Magdalena Thurin

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The "Great Debate" at Immunotherapy Bridge 2020, December 3rd, 2020., Paolo A Ascierto, Joshua Brody, Lisa H Butterfield, Olivera J Finn, John Goldberg, Francesco Perrone, Ryan J Sullivan, Bernard A Fox, Patrick Hwu, and Igor Puzanov

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The State of Melanoma: Emergent Challenges and Opportunities., Michael B Atkins, Clara Curiel-Lewandrowski, David E Fisher, Susan M Swetter, Hensin Tsao, Julio A Aguirre-Ghiso, Maria S Soengas, Ashani T Weeraratna, Keith T Flaherty, Meenhard Herlyn, Jeffrey A Sosman, Hussein A Tawbi, Anna C Pavlick, Pamela B Cassidy, Sunandana Chandra, Paul B Chapman, Adil Daud, Zeynep Eroglu, Laura K Ferris, Bernard A Fox, Jeffrey E Gerhsenwald, Geoffrey T Gibney, Douglas Grossman, Brent A Hanks, Douglas Hanniford, Eva Hernando, Joanne M Jeter, Douglas B Johnson, Samir N Khleif, John M Kirkwood, Sancy A Leachman, Darren Mays, Kelly C Nelson, Vernon K Sondak, Ryan J Sullivan, and Glenn Merlino

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DREAMseq (Doublet, Randomized Evaluation in Advanced Melanoma Sequencing): A phase III trial—ECOG-ACRIN EA6134, Michael B. Atkins, Brendan Curti, and See full list of authors in comments

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Phase I Trial of Cemiplimab, Radiotherapy, Cyclophosphamide, and Granulocyte Macrophage Colony-Stimulating Factor in Patients with Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma., Hani Babiker, Irene Brana, Daruka Mahadevan, Taofeek Owonikoko, Emiliano Calvo, Danny Rischin, Victor Moreno, Kyriakos P Papadopoulos, Marka Crittenden, Silvia Formenti, Jordi Giralt, Pilar Garrido, Ainara Soria, Asunción Hervás-Morón, Kosalai Kal Mohan, Matthew Fury, Israel Lowy, Melissa Mathias, Minjie Feng, Jingjin Li, and Elizabeth Stankevich

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Arginase therapy combines effectively with checkpoint blockade or agonist anti-OX40 immunotherapy to control tumor growth., Mark D Badeaux, Annah S Rolig, Giulia Agnello, Danlee Enzler, Melissa Kasiewicz, Leslie Priddy, Jason F Wiggins, Alexander Muir, Mark R Sullivan, Jessica Van Cleef, Christopher Daige, Matthew G Vander Heiden, Venkatesh Rajamanickam, James Wooldridge, William L. Redmond, and Scott W Rowlinson

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CXCL11 and SMICA as predictive biomarkers for efficacy of anti-CTLA4 immunotherapy, Keith Sadoon Bahjat, Helena Maria Hoen, Yoshinobu Koguchi, and Alan J. Korman

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CXCL11 and SMICA as predictive biomarkers for efficacy of anti-CTLA4 immunotherapy, Keith Sandoon Bahjat, Helena Maria Hoen, Yoshinobu Koguchi, and Alan J. Korman

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Initial Safety Results from a Phase II Study of Acalabrutinib Plus RICE Followed By Autologous Hematopoietic Cell Transplantation and/or Acalabrutinib Maintenance Therapy for Patients with Relapsed/Refractory Diffuse Large B-Cell Lymphoma, Neil Bailey, Tenzin Tsomo, Tori Braun, Jennie Szeto, William Bensinger, Daniel N Egan, Raya Mawad, Livia Hegerova, Gayle Funk, Joanna Fesler, Megumi Bailey, John M Pagel, and Krish Patel

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Immune-based mutation classification enables neoantigen prioritization and immune feature discovery in cancer immunotherapy., Peng Bai, Yongzheng Li, Qiuping Zhou, Jiaqi Xia, Peng-Cheng Wei, Hexiang Deng, Min Wu, Sanny K Chan, John W Kappler, Yu Zhou, Eric Tran, Philippa Marrack, and Lei Yin

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Prevalence and Correlates of Successful Smoking Cessation in Bladder Cancer Survivors., Jeffrey C Bassett, Richard S Matulewicz, Lorna Kwan, William J McCarthy, John L Gore, and Christopher S Saigal

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A national database propensity score-matched comparison of minimally invasive and open colectomy for long-term opioid use., Amir L Bastawrous, Kara K Brockhaus, Melissa I Chang, Gediwon Milky, I-Fan Shih, Yanli Li, and Robert K Cleary

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Amivantamab in combination with lazertinib for the treatment of osimertinib-relapsed, chemotherapy-naïve EGFR mutant (EGFRm) non-small cell lung cancer (NSCLC) and potential biomarkers for response., Joshua Bauml, Byoung Chul Cho, Rachel E Sanborn, and See full author list in comments

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Adjuvant Therapy for Stage II Colon Cancer: ASCO Guideline Update., Nancy N Baxter, Erin B Kennedy, Emily Bergsland, Jordan Berlin, Thomas J George, Sharlene Gill, Philip J Gold, Alex Hantel, Lee Jones, Christopher Lieu, Najjia Mahmoud, Arden M Morris, Erika Ruiz-Garcia, Y Nancy You, and Jeffrey A Meyerhardt

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Identifying breast cancer recurrence histories via patient-reported outcomes., J David Beatty, Qin Sun, Daniel Markowitz, Jessica Chubak, Bin Huang, and Ruth Etzioni

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The miR-181a-SFRP4 axis regulates Wnt activation to drive stemness and platinum resistance in ovarian cancer., Anil Belur Nagaraj, Matthew Knarr, Sreeja Sekhar, R Shae Connor, Peronne Joseph, Olga Kovalenko, Alexis Fleming, Arshia Surti, Elmar Nurmemmedov, Luca Beltrame, Sergio Marchini, Michael Kahn, and Analisa DiFeo

The virtual molecular tumor board as a tool for the delivery of precision oncology, Carlo Bifulco

10. Dendritic cell migration is required for the immunological responsiveness of tumors to radiation therapy, TC Blair, G Kramer, S Bambina, A Dowdell, AF Alice, Brian D. Piening, Marka R Crittenden, and MJ Gough

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Minimally invasive esophagectomy., Adam J Bograd and Daniela Molena

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Salvage Pulmonary Resections After Definitive Chemoradiotherapy., Adam J Bograd and Eric Vallieres

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DNA Damage Response in Glioblastoma: Mechanism for Treatment Resistance and Emerging Therapeutic Strategies., Alipi Bonm and Santosh Kesari

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Marizomib alone or in combination with bevacizumab in patients with recurrent glioblastoma: Phase I/II clinical trial data., Daniela A Bota, Warren Mason, Santosh Kesari, Rajiv Magge, Benjamin Winograd, Ileana Elias, Steven D Reich, Nancy Levin, Mohit Trikha, and Annick Desjardins

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Impact of rurality on melanoma diagnosis in Utah., Tawnya L Bowles, Carol Sweeney, John Snyder, Jesse Gygi, Brad Bott, Daniel Wray, Timothy J Yeatman, and William T Sause

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Merkel cell carcinoma can be indolent: A case with 7 locoregional recurrences over 15 years highlights the importance of patient-tailored management., Alyssa Breneman, Tomoko Akaike, Kelly G Paulson, Debra L Breneman, and Paul Nghiem

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165 Generating enhanced tumor infiltrating lymphocytes through microfluidic cell squeezing, Devin Bridgen, Andrew D Weinberg, and See full list of authors in comments

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A Randomized Study of Lenvatinib 18 mg Vs 24 mg in Patients With Radioiodine-Refractory Differentiated Thyroid Cancer., Marcia S Brose, Yury Panaseykin, Bhavana Konda, Christelle de La Fouchardiere, Brett G M Hughes, Andrew G Gianoukakis, Young Joo Park, Ilia Romanov, Monika K Krzyzanowska, Sophie Leboulleux, Terri A Binder, Corina Dutcus, Ran Xie, and Matthew H Taylor

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Incidence and risk factors for sustained hepatic function toxicity 6 months after radioembolization: analysis of the radiation-emitting sir-spheres in non-resectable liver tumor (RESIN) registry., Daniel Brown, Henry Krebs, Jayson Brower, Ryan O'Hara, Eric Wang, Kirubahara Vaheesan, Liping Du, Lea Matsuoka, Donna D'Souza, Daniel Y Sze, Jafar Golzarian, Ripal Gandhi, and Andrew Kennedy

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Cardiovascular adverse events in patients with chronic lymphocytic leukemia receiving acalabrutinib monotherapy: pooled analysis of 762 patients., Jennifer R Brown, John C Byrd, Paolo Ghia, Jeff P Sharman, Peter Hillmen, Deborah M Stephens, Clare Sun, Wojciech Jurczak, John M Pagel, Alessandra Ferrajoli, Priti Patel, Lin Tao, Nataliya Kuptsova-Clarkson, Javid Moslehi, and Richard R Furman

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Imaging Administrators: The Overlooked Barrier to Lung Cancer Screening Implementation., Kerrie E Buehler, Candice L Wilshire, Christopher R Gilbert, and Jed A Gorden

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A case of metachronous bilateral secretory carcinoma., Jessica Burlile, Andrea Collins, Joaquin Garcia, Kristin Gendron, Danielle Cunningham, and Robert Foote

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The benefits of fasting for patients who are immunocompromised and undergoing cancer treatment: An integrative research review, Lori Burnett

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A first-in-human study of AO-176, a highly differentiated anti-CD47 antibody, in patients with advanced solid tumors., Howard A. Burris III, Alexander I. Spira, and Matthew H Taylor

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Acalabrutinib in Treatment-Naïve Chronic Lymphocytic Leukemia., John C Byrd, Jennifer A Woyach, Richard R Furman, Peter Martin, Susan O'Brien, Jennifer R Brown, Deborah M Stephens, Jacqueline Barrientos, Stephen Devereux, Peter Hillmen, John M Pagel, Ahmed Hamdy, Raquel Izumi, Priti Patel, Min Hui Wang, Nitin Jain, and William George Wierda

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Nonpeptidic, Polo-Box Domain-Targeted Inhibitors of PLK1 Block Kinase Activity, Induce Its Degradation and Target-Resistant Cells., Danda Chapagai, Gurusankar Ramamoorthy, Jessy Varghese, Elmar Nurmemmedov, Campbell McInnes, and Michael D Wyatt

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Portable air-fed cold atmospheric plasma device for postsurgical cancer treatment., Guojun Chen, Zhitong Chen, Zejun Wang, Richard Obenchain, Di Wen, Hongjun Li, Richard E Wirz, and Zhen Gu

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Impact of new cancer therapies on outpatient treatment delivery for colorectal cancer: A population-based study., Leo Chen, Caroline H Speers, Winson Y Cheung, John J Spinelli, and Hagen F Kennecke

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Primary Chemoablation of Low-Grade Intermediate-Risk Non-Muscle-Invasive Bladder Cancer Using UGN-102, A Mitomycin-Containing Reverse Thermal Gel (Optima II): A Phase 2b, Open-Label, Single-Arm Trial., K Kent Chevli, Neal D Shore, Andrew Trainer, Angela B Smith, Daniel Saltzstein, Yaron Ehrlich, Jay D Raman, Boris Friedman, Richard D'Anna, David Morris, Brian Hu, Mark Tyson, Alexander Sankin, Max Kates, Jennifer Linehan, Douglas Scherr, Steven Kester, Michael Verni, Karim Chamie, Lawrence Karsh, Arnold Cinman, Andrew Meads, Soumi Lahiri, Madlen Malinowski, Nimrod Gabai, Sunil Raju, Mark Schoenberg, Elyse Seltzer, and William C Huang

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Subgroup analysis of nelipepimut-S plus GM-CSF combined with trastuzumab versus trastuzumab alone to prevent recurrences in patients with high-risk, HER2 low-expressing breast cancer., R Connor Chick, G Travis Clifton, Diane F Hale, Timothy J Vreeland, Annelies T Hickerson, Phillip M Kemp Bohan, Patrick M McCarthy, Jennifer K Litton, Gheath Alatrash, Rashmi K Murthy, Na Qiao, Anne Philips, Jason Lukas, Jarrod P Holmes, Elizabeth A Mittendorf, and George E Peoples

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Undifferentiated Carcinoma With Osteoclast-Like Giant Cells of the Pancreas Discovered on Positron Emission Tomography Performed for Lymphoma Staging., Wade O Christopher, Trevan D Fischer, and Anton J Bilchik

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SNO 2020 diversity survey: defining demographics, racial biases, career success metrics and a path forward for the field of neuro-oncology., Ugonma N Chukwueke, Elizabeth Vera, Alvina Acquaye, Shawn L Hervey-Jumper, Yazmin Odia, Laura J Klesse, Erin Dunbar, Akanksha Sharma, Ekokobe Fonkem, Alissa A Thomas, Tamra E Werbowetski-Ogilvie, Sandra Camelo-Piragua, Na Tosha N Gatson, Macarena I de la Fuente, Terri S Armstrong, Alyx B Porter, and Sadhana Jackson

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P2-14-07. Marrow-infiltrating lymphocytes as adoptive immunotherapy for breast cancer, Brie Chun, Nicole E. Fredich, David B Page, and See all authors in comments

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94 Effects of chemoimmunotherapy on the peripheral blood: insights from immune monitoring of a phase Ib trial of pembrolizumab and paclitaxel or capecitabine for triple-negative breast cancer (TNBC), Brie Chun, Joanna Pucilowska, Shu-Ching Chang, Isaac Kim, Benjamin Nikitin, Yoshinobu Koguchi, William L. Redmond, Brady Bernard, Venkatesh Rajamanickam, Nathan Polaske, Paul Fields, Valerie Conrad, Mark Schmidt, Walter Urba, Alison Conlin, Heather McArthur, and David B Page

​Effects of chemoimmunotherapy on the peripheral blood: insights from immune monitoring of a phase Ib trial of pembrolizumab and paclitaxel or capecitabine for triple-negative breast cancer (TNBC), Brie Chun, Joanna Pucilowska, Shu-Ching Chang, Isaac Kim, Benjamin Nikitin, Yoshinobu Koguchi, William L. Redmond, Brady Bernard, Venkatesh Rajamanickam, Nathan Polaske, Paul Fields, Valerie Conrad, Mark Schmidt, Walter Urba, Alison Conlin, Heather McArthur, and David B Page

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Neoadjuvant T-DM1/pertuzumab and paclitaxel/trastuzumab/pertuzumab for HER2, Amy S Clark, Christina Yau, Denise M Wolf, Emanuel F Petricoin, Laura J van 't Veer, Douglas Yee, Stacy L Moulder, Anne M Wallace, A Jo Chien, Claudine Isaacs, Judy C Boughey, Kathy S Albain, Kathleen Kemmer, Barbara B Haley, Hyo S Han, Andres Forero-Torres, Anthony Elias, Julie E Lang, Erin D Ellis, Rachel Yung, Debu Tripathy, Rita Nanda, Julia D Wulfkuhle, Lamorna Brown-Swigart, Rosa I Gallagher, Teresa Helsten, Erin Roesch, Cheryl A Ewing, Michael Alvarado, Erin P Crane, Meredith Buxton, Julia L Clennell, Melissa Paoloni, Smita M Asare, Amy Wilson, Gillian L Hirst, Ruby Singhrao, Katherine Steeg, Adam Asare, Jeffrey B Matthews, Scott Berry, Ashish Sanil, Michelle Melisko, Jane Perlmutter, Hope S Rugo, Richard B Schwab, W Fraser Symmans, Nola M Hylton, Donald A Berry, Laura J Esserman, and Angela M DeMichele

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Long-term progression-free survival of patients with metastatic melanoma or renal cell carcinoma following high-dose interleukin-2., Joseph I Clark, Brendan Curti, Elizabeth J Davis, Howard Kaufman, Asim Amin, Ajjai Alva, Theodore F Logan, Ralph Hauke, Gerald P Miletello, Ulka Vaishampayan, Douglas B Johnson, Richard L White, Peter H Wiernik, and Janice P Dutcher

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Interim results of viagenpumatucel-L (HS-110) plus nivolumab in previously treated patients (pts) with advanced non-small cell lung cancer (NSCLC) in two treatment settings., Roger B. Cohen, George E. Peoples, Rachel E Sanborn, and See list of authors in comments

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Phase I study of single agent NIZ985, a recombinant heterodimeric IL-15 agonist, in adult patients with metastatic or unresectable solid tumors., Kevin Conlon, Dionysios C Watson, Thomas A Waldmann, Antonio Valentin, Cristina Bergamaschi, Barbara K Felber, Cody J Peer, William D Figg, E Lake Potter, Mario Roederer, Douglas G McNeel, John A Thompson, Sumati Gupta, Rom Leidner, Andrea Wang-Gillam, Nehal S Parikh, Debby Long, Sema Kurtulus, Lang Ho Lee, Niladri Roy Chowdhury, Florent Bender, and George N Pavlakis

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Implementation of human papillomavirus video education for women participating in mass cervical cancer screening in Tanzania., Emma C Cooper, Justine A Maher, Ariana Naaseh, Elizabeth W Crawford, Justine O Chinn, Ava S Runge, Alexa N Lucas, Danielle C Zezoff, Kevin R Bera, Andreea I Dinicu, Kayla M White, Sujata E Tewari, Anjali Hari, Megan Bernstein, Jenny Chang, Argyrios Ziogas, Diana C Pearre, and Krishnansu S Tewari

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Combinations of stereotactic radiotherapy and immune checkpoint inhibition: Translational analyses, Marka R Crittenden

Integrating Radiation Therapy with Immunotherapy, Marka R Crittenden

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My surgical practice: Presenting aesthetic flat closure as an equal option to mastectomy with reconstruction and technical considerations to optimize cosmesis., Angelena Crown and Claire Buchanan

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Recent Advances in the Treatment of Melanoma., Brendan D Curti and Mark B Faries

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Enhancing clinical and immunological effects of anti-PD-1 with belapectin, a galectin-3 inhibitor., Brendan D Curti, Yoshinobu Koguchi, Rom S Leidner, Annah S Rolig, Elizabeth R Sturgill, Zhaoyu Sun, Yaping Wu, Venkatesh Rajamanickam, Brady Bernard, Ian Hilgart-Martiszus, Christopher B Fountain, George Morris, Noriko Iwamoto, Takashi Shimada, ShuChing Chang, Peter G Traber, Eliezer Zomer, J Rex Horton, Harold Shlevin, and William L Redmond

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381 Intratumoral oncolytic virus V937 plus ipilimumab in patients with advanced melanoma: the phase 1b MITCI study, Brendan Curti and See full list of authors in comments

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Laboratory and Clinical Implications of Incidental and Secondary Germline Findings During Tumor Testing., Allison Cushman-Vokoun, Josh Lauring, John Pfeifer, Damon R Olson, Anna Berry, John Thorson, Karl Voelkerding, Jonathan Myles, James Barbeau, Pranil Chandra, Marilyn Li, Gail H Vance, Brad W Jensen, Molly Y Hansen, and Sophia Yohe

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Lung epithelial and endothelial damage, loss of tissue repair, inhibition of fibrinolysis, and cellular senescence in fatal COVID-19., Felice D'Agnillo, Kathie-Anne Walters, Yongli Xiao, Zong-Mei Sheng, Kelsey Scherler, Jaekeun Park, Sebastian Gygli, Luz Angela Rosas, Kaitlyn Sadtler, Heather Kalish, Charles A Blatti, Ruoqing Zhu, Lisa Gatzke, Colleen Bushell, Matthew J Memoli, Steven O'Day, Trevan Fischer, Terese C Hammond, Raymond C Lee, J Christian Cash, Matthew E Powers, Grant E O'Keefe, Kelly J Butnor, Amy V Rapkiewicz, William D Travis, Scott P Layne, John C Kash, and Jeffery K Taubenberger

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Platinum resistance in gynecologic malignancies: Response, disease free and overall survival are predicted by biochemical signature: A metabolomic analysis., Paulo D'Amora, Ismael Dale C G Silva, Krishnansu S Tewari, Robert E Bristow, Fabio Cappuccini, Steven S Evans, Marcia B Salzgeber, Paula J Addis-Bernard, Anton M Palma, Dirce M L Marchioni, Antonio A F Carioca, Kristine R Penner, Jill Alldredge, Teresa Longoria, and Robert A Nagourney

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Correction to: Gliosarcoma vs. glioblastoma: a retrospective case series using molecular profiling., Christopher Dardis, David Donner, Nader Sanai, Joanne Xiu, Sandeep Mittal, Sharon K Michelhaugh, Manjari Pandey, Santosh Kesari, Amy B Heimberger, Zoran Gatalica, Michael W Korn, Ashley L Sumrall, and Surasak Phuphanich

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Gliosarcoma vs. glioblastoma: a retrospective case series using molecular profiling., Christopher Dardis, David Donner, Nader Sanai, Joanne Xiu, Sandeep Mittal, Sharon K Michelhaugh, Manjari Pandey, Santosh Kesari, Amy B Heimberger, Zoran Gatalica, Michael W Korn, Ashley L Sumrall, and Surasak Phuphanich

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Double-blind, randomized placebo-controlled trial of 8-week self-administered at-home behavioral skills-based virtual reality (VR) for chronic low back pain (during COVID-19)., Beth Darnall, Laura Garcia, Brandon Birckhead, Parthasarathy Krishnamurthy, Ian Mackey, Josh Sackman, Robert Louis, and Todd Maddox

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Clinical Utility of, Jeeban P Das, Hebert A Vargas, Soleen Ghafoor, Alvin C Goh, and Gary A Ulaner

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474 Phase 1 study of SEA-TGT, a human, nonfucosylated anti-TIGIT monoclonal antibody with enhanced immune-effector function, in patients with advanced malignancies (SGNTGT-001, trial in progress), Diwakar Davar, Rachel E Sanborn, and See full list of authors in comments

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Integrated safety analysis of umbralisib, a dual PI3Kδ/CK1ε inhibitor, in relapsed/refractory lymphoid malignancies., Matthew S Davids, Owen A O'Connor, Wojciech Jurczak, Felipe Samaniego, Timothy S Fenske, Pier Luigi Zinzani, Manish R Patel, Nilanjan Ghosh, Bruce D Cheson, Enrico Derenzini, Danielle M Brander, James A Reeves, Wanda Knopinska-Posluszny, John N Allan, Tycel Phillips, Paolo F Caimi, Ewa Lech-Maranda, John M Burke, Richy Agajanian, Ruth Pettengell, Lori A Leslie, Chan Y Cheah, Gustavo Fonseca, James H Essell, Julio C Chavez, John M Pagel, Jeff P Sharman, Yanzhi Hsu, Hari P Miskin, Peter Sportelli, Michael S Weiss, and Ian W Flinn

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Radiation dose and fraction in immunotherapy: one-size regimen does not fit all settings, so how does one choose?, Sandra Demaria, Chandan Guha, Jonathan Schoenfeld, Zachary Morris, Arta Monjazeb, Andrew Sikora, Marka Crittenden, Stephen Shiao, Samir Khleif, Seema Gupta, Silvia Chiara Formenti, Bhadrasain Vikram, C Norman Coleman, and Mansoor M Ahmed

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Open-Label Phase II Prospective, Randomized, Controlled Study of Romyelocel-L Myeloid Progenitor Cells to Reduce Infection During Induction Chemotherapy for Acute Myeloid Leukemia., Pinkal M Desai, Janice Brown, Saar Gill, Melham M Solh, Luke P Akard, Jack W Hsu, Celalettin Ustun, Charalambos Andreadis, Olga Frankfurt, James M Foran, John Lister, Gary J Schiller, Matthew J Wieduwilt, John M Pagel, Patrick J Stiff, Delong Liu, Irum Khan, Wendy Stock, Suman Kambhampati, Martin S Tallman, Lawrence Morris, John Edwards, Iskra Pusic, Hagop M Kantarjian, Richard Mamelok, Alicia Wong, Rodney Van Syoc, Lois Kellerman, Swapna Panuganti, Ramkumar Mandalam, Camille N Abboud, and Farhad Ravandi

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Bempegaldesleukin Plus Nivolumab in First-Line Metastatic Melanoma., Adi Diab, Scott S Tykodi, Gregory A Daniels, Michele Maio, Brendan D Curti, Karl D Lewis, Sekwon Jang, Ewa Kalinka, Igor Puzanov, Alexander I Spira, Daniel C Cho, Shanhong Guan, Erika Puente, Tuan Nguyen, Ute Hoch, Sue L Currie, Wei Lin, Mary A Tagliaferri, Jonathan Zalevsky, Mario Sznol, and Michael E Hurwitz

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Disparities in Amputation Rates for Non-metastatic Extremity Soft Tissue Sarcomas and the Impact on Survival., Joshua C Dilday, Daniel W Nelson, Trevan D Fischer, and Melanie Goldfarb

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Alkylaminophenol and GPR17 Agonist for Glioblastoma Therapy: A Combinational Approach for Enhanced Cell Death Activity., Phuong Doan, Phung Nguyen, Akshaya Murugesan, Nuno R Candeias, Olli Yli-Harja, and Meenakshisundaram Kandhavelu

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Targeting Orphan G Protein-Coupled Receptor 17 with T0 Ligand Impairs Glioblastoma Growth., Phuong Doan, Phung Nguyen, Akshaya Murugesan, Kumar Subramanian, Saravanan Konda Mani, Vignesh Kalimuthu, Bobin George Abraham, Brett W Stringer, Kadalmani Balamuthu, Olli Yli-Harja, and Meenakshisundaram Kandhavelu

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First-In-Human, First-In-Class, Phase I Trial of the Fucosylation Inhibitor SGN-2FF in Patients with Advanced Solid Tumors., Khanh T Do, Laura Quan Man Chow, Karen Reckamp, Rachel E Sanborn, Howard Burris, Francisco Robert, D Ross Camidge, Conor E Steuer, John H Strickler, Amy Weise, Jennifer M Specht, Martin Gutierrez, Peter Haughney, Shawna Hengel, Christina Louise Derleth, and Timothy A Yap

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Cancer case trends following the onset of the COVID-19 pandemic: A community-based observational study with extended follow-up., Charles W Drescher, Adam J Bograd, Shu-Ching Chang, Roshanthi Weerasinghe, Ann Vita, and Richard Bryan Bell

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Effect of Use of a Bougie vs Endotracheal Tube With Stylet on Successful Intubation on the First Attempt Among Critically Ill Patients Undergoing Tracheal Intubation: A Randomized Clinical Trial., Brian E Driver, Matthew W Semler, Wesley H Self, Adit A Ginde, Stacy A Trent, Sheetal Gandotra, Lane M Smith, David B Page, Derek J Vonderhaar, Jason R West, Aaron M Joffe, Steven H Mitchell, Kevin C Doerschug, Christopher G Hughes, Kevin High, Janna S Landsperger, Karen E Jackson, Michelle P Howell, Sarah W Robison, John P Gaillard, Micah R Whitson, Christopher M Barnes, Andrew J Latimer, Vikas S Koppurapu, Bret D Alvis, Derek W Russell, Kevin W Gibbs, Li Wang, Christopher J Lindsell, David R Janz, Todd W Rice, Matthew E Prekker, Jonathan D Casey, and BOUGIE Investigators and the Pragmatic Critical Care Research Group

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The Impact of Chronic Kidney Disease in Patients With Locally Advanced Rectal Cancer Treated With Neoadjuvant Chemoradiation., Shaan Dudani, Horia Marginean, Joanna Gotfrit, Patricia A Tang, Jose Gerard Monzon, Kristopher Dennis, Hagen F Kennecke, Erin D Powell, Sam Babak, Winson Y Cheung, and Michael M Vickers

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Neoadjuvant anti-OX40 (MEDI6469) therapy in patients with head and neck squamous cell carcinoma activates and expands antigen-specific tumor-infiltrating T cells., Rebekka Duhen, Carmen Ballesteros-Merino, Alexandra K Frye, Eric Tran, Venkatesh Rajamanickam, Shu-Ching Chang, Yoshinobu Koguchi, Carlo Bifulco, Brady Bernard, Rom Leidner, Brendan Curti, Bernard A Fox, Walter Urba, Richard Bryan Bell, and Andrew D Weinberg

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Neoadjuvant talimogene laherparepvec plus surgery versus surgery alone for resectable stage IIIB-IVM1a melanoma: a randomized, open-label, phase 2 trial., R Dummer, D E Gyorki, J Hyngstrom, A C Berger, R Conry, L Demidov, A Sharma, S A Treichel, H Radcliffe, K S Gorski, A Anderson, E Chan, M Faries, and M I Ross

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Cabozantinib: An evolving therapy for hepatocellular carcinoma., Anthony B El-Khoueiry, Diana L Hanna, Josep Llovet, and Robin Kate Kelley

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Modified RANO, Immunotherapy RANO, and Standard RANO Response to Convection-Enhanced Delivery of IL4R-Targeted Immunotoxin MDNA55 in Recurrent Glioblastoma., Benjamin M Ellingson, John Sampson, Achal Singh Achrol, Manish K Aghi, Krystof Bankiewicz, Chencai Wang, Martin Bexon, Steven Brem, Andrew Brenner, Sajeel Chowdhary, John R Floyd, Seunggu Han, Santosh Kesari, Dina Randazzo, Michael A Vogelbaum, Frank Vrionis, Miroslaw Zabek, Nicholas Butowski, Melissa Coello, Nina Merchant, and Fahar Merchant

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Cryopreserved placental tissue allograft accelerates time to continence following robot-assisted radical prostatectomy., Peter A Elliott, Stephanie Hsiang, Ramkishen Narayanan, James Bierylo, Shu-Ching Chang, Przemyslaw Twardowski, and Timothy G Wilson

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Society for Immunotherapy of Cancer (SITC) clinical practice guideline on immunotherapy for the treatment of breast cancer., Leisha A Emens, Sylvia Adams, Ashley Cimino-Mathews, Mary L Disis, Margaret E Gatti-Mays, Alice Y Ho, Kevin Kalinsky, Heather L McArthur, Elizabeth A Mittendorf, Rita Nanda, David B Page, Hope S Rugo, Krista M Rubin, Hatem Soliman, Patricia A Spears, Sara M Tolaney, and Jennifer K Litton

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Enhancing the generation of Eomeshi CD8+ T cells augment the efficacy of OX40- and CTLA-4-targeted immunotherapy., Dana A Emerson, Annah S Rolig, and William L. Redmond

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Are There Limits in Explainability of Prognostic Biomarkers? Scrutinizing Biological Utility of Established Signatures., Frank Emmert-Streib, Kalifa Manjang, Matthias Dehmer, Olli Yli-Harja, and Anssi Auvinen

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Current Triple-Negative Breast Cancer Subtypes: Dissecting the Most Aggressive Form of Breast Cancer., Miquel Ensenyat-Mendez, Pere Llinàs-Arias, Javier I J Orozco, Sandra Íñiguez-Muñoz, Matthew P Salomon, Borja Sesé, Maggie L DiNome, and Diego M Marzese

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Comparative analysis of targeted novel therapies in relapsed, refractory chronic lymphocytic leukaemia., Toby A Eyre, Nicole Lamanna, Lindsey E Roeker, Chaitra S Ujjani, Brian T Hill, Paul M Barr, Erick Lansigan, Bruce D Cheson, Maryam Yazdy, John N Allan, Joanna Rhodes, Stephen J Schuster, Chadi Nabhan, Alan Skarbnik, Lori Leslie, Prioty Islam, Katherine Whitaker, Catherine C Coombs, Hande H Tuncer, John M Pagel, Ryan Jacobs, Allison M Winter, Neil Bailey, Andrea Sitlinger, Anna H Schuh, George Follows, Christopher P Fox, Danielle M Brander, Mazyar Shadman, and Anthony R Mato

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Acalabrutinib monotherapy for treatment of chronic lymphocytic leukaemia (ACE-CL-001): analysis of the Richter transformation cohort of an open-label, single-arm, phase 1-2 study., Toby A Eyre, Anna Schuh, William G Wierda, Jennifer R Brown, Paolo Ghia, John M Pagel, Richard R Furman, Jean Cheung, Ahmed Hamdy, Raquel Izumi, Priti Patel, Min Hui Wang, Yan Xu, John C Byrd, and Peter Hillmen

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Challenges and Errors in Genetic Testing: The Fifth Case Series., Meagan B Farmer, Danielle C Bonadies, Holly J Pederson, Kathryn A Mraz, Julie W Whatley, Deanna R Darnes, Jessica Johnson Denton, Diana De Rosa, Alexis Heatherly, Jessica Kenney, Kimberly Lane, Deborah Paul, Renée C Pelletier, Kristen Shannon, Danielle Williams, and Ellen T Matloff

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Challenges and Errors in Genetic Testing: The Fifth Case Series., Meagan B Farmer, Danielle C Bonadies, Holly J Pederson, Kathryn A Mraz, Julie W Whatley, Deanna R Darnes, Jessica Johnson Denton, Diana De Rosa, Alexis Heatherly, Jessica Kenney, Kimberly Lane, Deborah Paul, Renée C Pelletier, Kristen Shannon, Danielle Williams, and Ellen T Matloff

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CD8-targeted PET Imaging of Tumor Infiltrating T cells in Patients with Cancer: A Phase I First-in-Human Study of, Michael D Farwell, Raymond F Gamache, Hasan Babazada, Matthew D Hellmann, James J Harding, Ron Korn, Alessandro Mascioni, William Le, Ian Wilson, Michael S Gordon, Anna M Wu, Gary A Ulaner, Jedd D Wolchok, Michael A Postow, and Neeta A Pandit-Taskar

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NCI Imaging Data Commons., Andrey Fedorov, William J R Longabaugh, David Pot, David A Clunie, Steve Pieper, Hugo J W L Aerts, André Homeyer, Rob Lewis, Afshin Akbarzadeh, Dennis Bontempi, William Clifford, Markus D Herrmann, Henning Höfener, Igor Octaviano, Chad Osborne, Suzanne Paquette, James Petts, Davide Punzo, Madelyn Reyes, Daniela P Schacherer, Mi Tian, George White, Erik Ziegler, Ilya Shmulevich, Todd Pihl, Ulrike Wagner, Keyvan Farahani, and Ron Kikinis

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383 Durable responses with intratumoral electroporation of plasmid interleukin 12 plus pembrolizumab in patients with advanced melanoma progressing on an anti-PD-1 antibody: updated data from keynote 695, Pablo Fernandez-Penas, Carmen Ballesteros-Merino, Shawn M. Jensen, Bernard A Fox, and See full list of authors in comments

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Trilaciclib prior to chemotherapy reduces the usage of supportive care interventions for chemotherapy-induced myelosuppression in patients with small cell lung cancer: Pooled analysis of three randomized phase 2 trials., Renata Ferrarotto, Ian Anderson, Balazs Medgyasszay, Maria Rosario García-Campelo, William Edenfield, Trevor M Feinstein, Jennifer M Johnson, Sujith Kalmadi, Philip E Lammers, Alfredo Sanchez-Hernandez, Yili Pritchett, Shannon R Morris, Rajesh K Malik, and Tibor Csőszi

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Updated report of a phase II randomized trial of transoral surgical resection followed by low-dose or standard postoperative therapy in resectable p16+ locally advanced oropharynx cancer: A trial of the ECOG-ACRIN cancer research group (E3311)., Robert L. Ferris, Yael Flammand, Richard Bryan Bell, and See list of authors in comments

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Neoadjuvant nivolumab for patients with resectable HPV-positive and HPV-negative squamous cell carcinomas of the head and neck in the CheckMate 358 trial., Robert L Ferris, William C Spanos, Rom Leidner, Anthony Gonçalves, Uwe M Martens, Chrisann Kyi, William Sharfman, Christine H Chung, Lot A Devriese, Helene Gauthier, Simon I Chiosea, Lazar Vujanovic, Janis M Taube, Julie E Stein, Jun Li, Bin Li, Tian Chen, Adam Barrows, and Suzanne L Topalian

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Associations of practical, emotional, and physical problems with psychosocial distress among cancer patients., Mark William Flanagan, Heather H Goltz, John W Henson, and Matthew Lee Smith