The Cancer Institute is a leader in cutting-edge treatments. Using a truly multidisciplinary approach, patients have access to advanced diagnostics, minimally invasive surgical interventions, and personalized genomic and immune-oncologic treatment options. Our team of cancer specialists – many of whom completed fellowships and specialty training at prestigious academic centers – offers comprehensive services for individuals with a cancer diagnosis.

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Submissions from 2024

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PRESTO: A Phase III, Open-Label Study of Intensification of Androgen Blockade in Patients With High-Risk Biochemically Relapsed Castration-Sensitive Prostate Cancer (AFT-19)., Rahul Aggarwal, Glenn Heller, David W Hillman, Han Xiao, Joel Picus, Mary-Ellen Taplin, Tanya Dorff, Leonard Appleman, Douglas Weckstein, Akash Patnaik, Alan Bryce, Daniel Shevrin, James Mohler, Daniel Anderson, Arpit Rao, Scott Tagawa, Alan Tan, Susan Halabi, Katharine Dooley, Patrick O'Brien, Ronald Chen, Charles J Ryan, Scott E Eggener, Michael J Morris, EORTC-55994 Study Group, and Brendan Curti (EORTC-55994 Study Group)

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Neoadjuvant Trebananib plus Paclitaxel-based Chemotherapy for Stage II/III Breast Cancer in the Adaptively Randomized I-SPY2 Trial-Efficacy and Biomarker Discovery., Kathy S Albain, Christina Yau, Emanuel F Petricoin, Denise M Wolf, Julie E Lang, A Jo Chien, Tufia Haddad, Andres Forero-Torres, Anne M Wallace, Henry G Kaplan, Lajos Pusztai, David Euhus, Rita Nanda, Anthony D Elias, Amy S Clark, Constantine Godellas, Judy C Boughey, Claudine Isaacs, Debu Tripathy, Janice Lu, Rachel L Yung, Rosa I Gallagher, Julia D Wulfkuhle, Lamorna Brown-Swigart, Gregor Krings, Yunn Yi Chen, David A Potter, Erica Stringer-Reasor, Sarah Blair, Smita M Asare, Amy Wilson, Gillian L Hirst, Ruby Singhrao, Meredith Buxton, Julia L Clennell, Ashish Sanil, Scott Berry, Adam L Asare, Jeffrey B Matthews, Angela M DeMichele, Nola M Hylton, Michelle Melisko, Jane Perlmutter, Hope S Rugo, W Fraser Symmans, Laura J Van't Veer, Douglas Yee, Donald A Berry, and Laura J Esserman

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A phase 1 study of triple-targeted therapy with BRAF, MEK, and AKT inhibitors for patients with BRAF-mutated cancers., Alain P Algazi, James Moon, Christopher D Lao, Bartosz Chmielowski, Kari L Kendra, Karl D Lewis, Rene Gonzalez, Kevin Kim, John E Godwin, Brendan D. Curti, Michaella Latkovic-Taber, Shirley H Lomeli, Brandon T Gufford, Philip O Scumpia, Roger S Lo, Megan Othus, and Antoni Ribas

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The Journey to Improve the College of American Pathologists Cancer Biomarker Reporting Protocols., Brett Baskovich, Alexander Baras, Raja R Seethala, Patrick L Fitzgibbons, Frank Schneider, Brent T Harris, and Joseph Khoury

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A Phase 1/2 Study to Evaluate the Safety and Activity of Nivolumab in Combination With Vorolanib, a Vascular Endothelial Growth Factor Tyrosine Kinase Inhibitor, in Patients With Refractory Thoracic Tumors., Kathryn E Beckermann, Christine M Bestvina, Badi El Osta, Rachel E Sanborn, Hossein Borghaei, Philip Edward Lammers, Giovanni Selvaggi, Jennifer G Whisenant, Ellen Heimann-Nichols, Lynne Berry, Chih-Yuan Hsu, Yu Shyr, Leora Horn, and Heather Wakelee

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Treatment practices and response in kaposiform hemangioendothelioma: A multicenter cohort study., Alexandra J Borst, Whitney Eng, Morgan Griffin, Kiersten W Ricci, Elissa Engel, Denise M Adams, Jillian Dayneka, Sally J Cohen-Cutler, Steven M Andreoli, Melinda D Wu, Allison P Wheeler, Kenneth M Heym, Shelley E Crary, Taizo A Nakano, Rachael R Schulte, Bhuvana A Setty, Thomas W McLean, Kristy S Pahl, Stefanos Intzes, Irina Pateva, Max Teitelbaum, Zili Zong, Yimei Li, and Michael R Jeng

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Sunitinib in Patients With Breast Cancer With, Carmen J Calfa, Michael Rothe, Pam K Mangat, Elizabeth Garrett-Mayer, Eugene R Ahn, Monika L Burness, Keerthi Gogineni, Nitin Rohatgi, Tareq Al Baghdadi, Alison Conlin, Anu Gaba, Omid Hamid, Jairam Krishnamurthy, Naga Jyothi Gavini, Philip J Gold, Jordi Rodon, Jens Rueter, Ramya Thota, Gina N Grantham, Dominique C Hinshaw, Abigail Gregory, Susan Halabi, and Richard L Schilsky

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MRI-derived radiomics assessing tumor-infiltrating macrophages enable prediction of immune-phenotype, immunotherapy response and survival in glioma., Di Chen, Rui Zhang, Xiaoming Huang, Chunxia Ji, Wei Xia, Ying Qi, Xinyu Yang, Lishuang Lin, Jing Wang, Haixia Cheng, Weijun Tang, Jinhua Yu, Dave S B Hoon, Jun Zhang, Xin Gao, and Yu Yao

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Preoperative immune checkpoint inhibition and cryoablation in early-stage breast cancer., Elizabeth Comen, Sadna Budhu, Yuval Elhanati, David B Page, Teresa Rasalan-Ho, Erika Ritter, Phillip Wong, George Plitas, Sujata Patil, Edi Brogi, Maxine Jochelson, Yolanda Bryce, Stephen B Solomon, Larry Norton, Taha Merghoub, and Heather L McArthur

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Consensus Recommendations on the Management of Toxicity Associated with CD3xCD20 Bispecific Antibody Therapy., Jennifer L Crombie, Tara Graff, Lorenzo Falchi, Yasmin H Karimi, Rajat Bannerji, Loretta J Nastoupil, Catherine Thieblemont, Renata Ursu, Nancy L Bartlett, Victoria R Nachar, Jonathan Weiss, Jane Osterson, Krish Patel, Joshua D Brody, Jeremy S Abramson, Matthew A Lunning, Nirav N Shah, Ayed Ayed, Manali Kamdar, Benjamin M Parsons, Paolo Caimi, Ian W Flynn, Alex F Herrera, Jeff P Sharman, Marshall McKenna, Philippe Armand, Brad S Kahl, Sonali M Smith, Andrew D Zelenetz, Lihua E Budde, Martin Hutchings, Tycel J Phillips, and Michael Dickinson

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Same day discharge colon surgery: is it financially worth it?, Karleigh R Curfman, Gabrielle E Blair, Callan L Kosnik, Sunshine A Pille, Michael E Parsons, Chirag A Shah, Christopher C Neighorn, and Laila Rashidi

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The future of targeting cytotoxic T-lymphocyte-associated protein-4: Is there a role?, Anna Maria Di Giacomo, Michael Lahn, Alexander Mm Eggermont, Bernard Fox, Ramy Ibrahim, Padmanee Sharma, James P Allison, and Michele Maio

Developing Combination Immunotherapy Trials with Vaccines that Contain Cancer’s Dark Matter, Bernard Fox

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A randomized phase III study of standard versus high-dose cytarabine with or without vorinostat for AML., Guillermo Garcia-Manero, Nikolai A Podoltsev, Megan Othus, John M Pagel, Jerald P Radich, Min Fang, David A Rizzieri, Guido Marcucci, Stephen A Strickland, Mark R Litzow, M Lynn Savoie, Bruno C Medeiros, Mikkael A Sekeres, Tara L Lin, Geoffrey L Uy, Bayard L Powell, Jonathan E Kolitz, Richard A Larson, Richard M Stone, David Claxton, James Essell, Selina M Luger, Sanjay R Mohan, Anna Moseley, Frederick R Appelbaum, and Harry P Erba

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Phase 1 trial of TPI 287, a microtubule stabilizing agent, in combination with bevacizumab in adults with recurrent glioblastoma., Samuel A Goldlust, Louis B Nabors, Sigmund Hsu, Nimish Mohile, Paul J Duic, Tara Benkers, Samuel Singer, Mayank Rao, Lori Cappello, Sandra L Silberman, and George Farmer

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Population Screening for High-Risk Patient Identification Partnership with CARE-Comprehensive Assessment, Risk, and Education., Ora K Gordon, Brad Bott, Nanor Parseghian, Kimberly K Childers, and Sandra Brown

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Multi-Cancer Early Detection Testing (MCED), Ora K Gordon, Brad Bott, Nanor Parseghian, Paul Psychogios, Kimberly K Childers, and Sandra Brown

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Characteristics and Survival Outcomes of Patients With Metastatic, Allan Hackshaw, Otto Fajardo, Urania Dafni, Hans Gelderblom, Pilar Garrido, Salvatore Siena, Matthew H Taylor, Walter Bordogna, and Christos Nikolaidis

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A phase 1/2 clinical trial of invariant natural killer T cell therapy in moderate-severe acute respiratory distress syndrome., Terese C Hammond, Marco A Purbhoo, Sapana Kadel, Jerome Ritz, Sarah Nikiforow, Heather Daley, Kit Shaw, Koen van Besien, Alexandra Gomez-Arteaga, Don Stevens, Waldo Ortuzar, Xavier Michelet, Rachel Smith, Darrian Moskowitz, Reed Masakayan, Burcu Yigit, Shannon Boi, Kah Teong Soh, John Chamberland, Xin Song, Yu Qin, Ilya Mishchenko, Maurice Kirby, Valeriia Nasonenko, Alexa Buffa, Jennifer S Buell, Dhan Chand, Marc van Dijk, Justin Stebbing, and Mark A Exley

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Smoking Status and Survival in Patients With Early-Stage Primary Cutaneous Melanoma., Katherine M Jackson, Peter C Jones, Laura M Fluke, Trevan D Fischer, John F Thompson, Alistair J Cochran, Stacey L Stern, Mark B Faries, Dave S B Hoon, and Leland J Foshag

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Image-based multiplex immune profiling of cancer tissues: translational implications. A report of the International Immuno-oncology Biomarker Working Group on Breast Cancer., Chowdhury Arif Jahangir, David B Page, Glenn Broeckx, Claudia A Gonzalez, Caoimbhe Burke, Clodagh Murphy, Jorge S Reis-Filho, Amy Ly, Paul W Harms, Rajarsi R Gupta, Michael Vieth, Akira I Hida, Mohamed Kahila, Zuzana Kos, Paul J van Diest, Sara Verbandt, Jeppe Thagaard, Reena Khiroya, Khalid Abduljabbar, Gabriela Acosta Haab, Balazs Acs, Sylvia Adams, Jonas S Almeida, Isabel Alvarado-Cabrero, Farid Azmoudeh-Ardalan, Sunil Badve, Nurkhairul Bariyah Baharun, Enrique R Bellolio, Vydehi Bheemaraju, Kim Rm Blenman, Luciana Botinelly Mendonça Fujimoto, Octavio Burgues, Alexandros Chardas, Maggie Chon U Cheang, Francesco Ciompi, Lee Ad Cooper, An Coosemans, Germán Corredor, Flavio Luis Dantas Portela, Frederik Deman, Sandra Demaria, Sarah N Dudgeon, Mahmoud Elghazawy, Claudio Fernandez-Martín, Susan Fineberg, Stephen B Fox, Jennifer M Giltnane, Sacha Gnjatic, Paula I Gonzalez-Ericsson, Anita Grigoriadis, Niels Halama, Matthew G Hanna, Aparna Harbhajanka, Steven N Hart, Johan Hartman, Stephen Hewitt, Hugo M Horlings, Zaheed Husain, Sheeba Irshad, Emiel Am Janssen, Tatsuki R Kataoka, Kosuke Kawaguchi, Andrey I Khramtsov, Umay Kiraz, Pawan Kirtani, Liudmila L Kodach, Konstanty Korski, Guray Akturk, Ely Scott, Anikó Kovács, Anne-Vibeke Laenkholm, Corinna Lang-Schwarz, Denis Larsimont, Jochen K Lennerz, Marvin Lerousseau, Xiaoxian Li, Anant Madabhushi, Sai K Maley, Vidya Manur Narasimhamurthy, Douglas K Marks, Elizabeth S McDonald, Ravi Mehrotra, Stefan Michiels, Durga Kharidehal, Fayyaz Ul Amir Afsar Minhas, Shachi Mittal, David A Moore, Shamim Mushtaq, Hussain Nighat, Thomas Papathomas, Frederique Penault-Llorca, Rashindrie D Perera, Christopher J Pinard, Juan Carlos Pinto-Cardenas, Giancarlo Pruneri, Lajos Pusztai, Nasir Mahmood Rajpoot, Bernardo Leon Rapoport, Tilman T Rau, Joana M Ribeiro, David Rimm, Anne Vincent-Salomon, Joel Saltz, Shahin Sayed, Evangelos Hytopoulos, Sarah Mahon, Kalliopi P Siziopikou, Christos Sotiriou, Albrecht Stenzinger, Maher A Sughayer, Daniel Sur, Fraser Symmans, Sunao Tanaka, Timothy Taxter, Sabine Tejpar, Jonas Teuwen, E Aubrey Thompson, Trine Tramm, William T Tran, Jeroen van der Laak, Gregory E Verghese, Giuseppe Viale, Noorul Wahab, Thomas Walter, Yannick Waumans, Hannah Y Wen, Wentao Yang, Yinyin Yuan, John Bartlett, Sibylle Loibl, Carsten Denkert, Peter Savas, Sherene Loi, Elisabeth Specht Stovgaard, Roberto Salgado, William M Gallagher, and Arman Rahman

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The RAPID Consortium: A Platform for Clinical and Translational Pituitary Tumor Research., Michael Karsy, Varun Kshettry, Paul Gardner, Michael Chicoine, Juan C Fernandez-Miranda, James J Evans, Garni Barkhoudarian, Douglas Hardesty, Won Kim, Gabriel Zada, Tomiko Crocker, Ildiko Torok, and Andrew Little

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Pilot Study of High-Dose Pemetrexed in Patients with Progressive Chordoma., Santosh Kesari, Naveed Wagle, Jose Carrillo, Akanksha Sharma, Minhdan Nguyen, Judy D Truong, Jaya Mini Gill, Raffi Nersesian, Natsuko Nomura, Elnaz Rahbarlayegh, Garni Barkhoudarian, Walavan Sivakumar, Daniel F Kelly, Howard Krauss, Matias A Bustos, Dave Hoon, Lars Anker, Arun S Singh, Kamalesh K Sankhala, and Tiffany Juarez

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Peristomal cutaneous amebiasis causing rapidly progressive necrotic wound of a left lower quadrant end colostomy., Debra Lai, Byung Kyu Kim, and Amir Bastawrous

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Evaluation of potential biomarkers for lenvatinib plus pembrolizumab among patients with advanced endometrial cancer: results from Study 111/KEYNOTE-146., Vicky Makker, Matthew H Taylor, Carol Aghajanian, Allen L Cohn, Marcia S Brose, Christopher Di Simone, Zhu Alexander Cao, Leah Suttner, Andrey Loboda, Razvan Cristescu, Petar Jelinic, Robert Orlowski, Lea Dutta, Junji Matsui, Corina E Dutcus, Yukinori Minoshima, and Mark J Messing

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The Dance Between Tumor Molecular Biology and Antitumor Immune Response., K A Margolin

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Tissue-specific thresholds of mutation burden associated with anti-PD-1/L1 therapy benefit and prognosis in microsatellite-stable cancers., Maishara Muquith, Magdalena Espinoza, Andrew Elliott, Joanne Xiu, Andreas Seeber, Wafik El-Deiry, Emmanuel S Antonarakis, Stephanie L Graff, Michael J Hall, Hossein Borghaei, Dave S B Hoon, Stephen V Liu, Patrick C Ma, Rana R McKay, Trisha Wise-Draper, John Marshall, George W Sledge, David Spetzler, Hao Zhu, and David Hsiehchen

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Imaging as an early biomarker to predict sensitivity to everolimus for progressive NF2-related vestibular schwannoma., Phioanh Leia Nghiemphu, Jeremie Vitte, Eva Dombi, Thien Nguyen, Naveed Wagle, Akira Ishiyama, Ali R Sepahdari, David Cachia, Brigitte C Widemann, Derald E Brackmann, Joni K Doherty, Michel Kalamarides, and Marco Giovannini

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Adjuvant Radiotherapy for Surgically Resected Stage III Merkel Cell Carcinoma., Seyed Saeed Pairawan, Chloe E Dominguez, Naveenraj Solomon, David Caba-Molina, Michael O'Leary, Mark E Reeves, and Jukes P Namm

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Gene regulatory network topology governs resistance and treatment escape in glioma stem-like cells., James H Park, Parvinder Hothi, Adrian Lopez Garcia de Lomana, Min Pan, Rachel Calder, Serdar Turkarslan, Wei-Ju Wu, Hwahyung Lee, Anoop P Patel, Charles Cobbs, Sui Huang, and Nitin S Baliga

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Posterior Ischemic Optic Neuropathy Because of Hematologic Malignancy., Ankush U Patel, Uresh S Patel, and Eugene May

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Circulating cancer-specific CD8 T cell frequency is associated with response to PD-1 blockade in Merkel cell carcinoma., Thomas Pulliam, Saumya Jani, Lichen Jing, Heeju Ryu, Ana Jojic, Carolyn Shasha, Jiajia Zhang, Rima Kulikauskas, Candice Church, Charlie Garnett-Benson, Ted Gooley, Aude Chapuis, Kelly G Paulson, Kellie N Smith, Drew M Pardoll, Evan W Newell, David M Koelle, Suzanne L Topalian, and Paul Nghiem

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Exercise-Related Physical Activity Relates to Brain Volumes in 10,125 Individuals., Cyrus A Raji, Somayeh Meysami, Sam Hashemi, Saurabh Garg, Nasrin Akbari, Gouda Ahmed, Yosef Gavriel Chodakiewitz, Thanh Duc Nguyen, Kellyann Niotis, David A Merrill, and Rajpaul Attariwala

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Norepinephrine induces anoikis resistance in high-grade serous ovarian cancer precursor cells., Hunter D Reavis, Stefan M Gysler, Grace B McKenney, Matthew Knarr, Hannah J Lusk, Priyanka Rawat, Hannah S Rendulich, Marilyn A Mitchell, Dara S Berger, Jamie Moon, Suyeon Ryu, Monica Mainigi, Marcin P Iwanicki, Dave Hoon, Laura M Sanchez, and Ronny Drapkin

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Exploring the Genomic Landscape of Hepatobiliary Cancers to Establish a Novel Molecular Classification System., Anthony J Scholer, Rebecca Marcus, Mary Garland-Kledzik, Debopriya Ghosh, Miquel Ensenyat-Mendez, Joshua Germany, Juan A Santamaria-Barria, Adam Khader, Javier I Orozco, and Melanie Goldfarb

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Early Experiences With Bundled Payments for Care Improvement for Major Bowel Surgery., Udai S Sibia, John R Klune, Said Saiolghalam, and Anton J Bilchik

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Analysis of 10-year trends in Medicare Physician Fee Schedule payments in surgery., Udai S Sibia, Janelle-Cheri Millen, John R Klune, Anton Bilchik, and Leland J Foshag

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A real-world study of treatment sequences and second-line clinical outcomes in patients with HER2-positive metastatic breast cancer in US community practice., Della Varghese, Giovanna I Cruz, Colden Johanson, Liz Toland, Miguel Miranda, Eleanor C Faherty, David Harland, and Henry G Kaplan

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Management of Neurologic Complications in Patients with Brain and Spine Tumors., Alipi V Bonm and Lynne P Taylor

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Individualised neoantigen therapy mRNA-4157 (V940) plus pembrolizumab versus pembrolizumab monotherapy in resected melanoma (KEYNOTE-942): a randomised, phase 2b study., Jeffrey S Weber, Matteo S Carlino, Adnan Khattak, Tarek Meniawy, George Ansstas, Matthew H Taylor, Kevin B Kim, Meredith McKean, Georgina V Long, Ryan J Sullivan, Mark Faries, Thuy T Tran, C Lance Cowey, Andrew Pecora, Montaser Shaheen, Jennifer Segar, Theresa Medina, Victoria Atkinson, Geoffrey T Gibney, Jason J Luke, Sajeve Thomas, Elizabeth I Buchbinder, Jane A Healy, Mo Huang, Manju Morrissey, Igor Feldman, Vasudha Sehgal, Celine Robert-Tissot, Peijie Hou, Lili Zhu, Michelle Brown, Praveen Aanur, Robert S Meehan, and Tal Zaks

Submissions from 2023

Deep Learning Applications Using H&E Images Improve Clinical Sequencing Workflows, J Abel, Brian Piening, Carlo Bifulco, and See full list of authors in comments

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Heterogeneity in the Metastatic Microenvironment: JunB-Expressing Microglia Cells as Potential Drivers of Melanoma Brain Metastasis Progression., Orit Adir, Orit Sagi-Assif, Tsipi Meshel, Shlomit Ben-Menachem, Metsada Pasmanik-Chor, Dave Hoon, Isaac P Witz, and Sivan Izraely

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Multi-omics inference of differential breast cancer-related transcriptional regulatory network gene hubs between young Black and White patients., Boris Aguilar, Kawther Abdilleh, and George K Acquaah-Mensah

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Pertuzumab Plus Trastuzumab in Patients With Endometrial Cancer With, Eugene R Ahn, Michael Rothe, Pam K Mangat, Elizabeth Garrett-Mayer, Hussein M Ali-Ahmad, John Chan, Michael L Maitland, Sapna R Patel, Zachary Reese, Ani S Balmanoukian, Charles W Drescher, Rui Li, Apostolia M Tsimberidou, Charles A Leath, Raegan O'Lone, Gina N Grantham, Susan Halabi, and Richard L Schilsky

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AAPM BTSC Report 377: Physicist Brachytherapy Training in 2021-A survey of therapeutic medical physics residency program directors., Manik Aima, Samantha J Simiele, Susan L Richardson, and Christopher S Melhus

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Case report: ex vivo tumor organoid drug testing identifies therapeutic options for stage IV ovarian carcinoma, Marwah Al-Aloosi, Amanda M Prechtl, Payel Chatterjee, Brady Bernard, Christopher J Kemp, Rachele Rosati, Robert L Diaz, Lauren R Appleyard, Shalini Pereira, Alex Rajewski, Amber McDonald, Eva J Gordon, and Carla Grandori

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Liquid biopsies and minimal residual disease in myeloid malignancies., Sabine Allam, Kristina Nasr, Farhan Khalid, Zunairah Shah, Mahammed Ziauddin Khan Suheb, Sana Mulla, Sindhu Vikash, Maroun Bou Zerdan, Faiz Anwer, and Chakra P Chaulagain

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Vemurafenib- and Cobimetinib-Associated Drug Reaction With Eosinophilia and Systemic Symptoms in a Patient With Metastatic Melanoma., Miriam Al-Saedy, Salsabeal Al-Saedy, and Chad Rieck

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Gut microbiota analyses of inflammatory bowel diseases from a representative Saudi population., Raed M Alsulaiman, Abdulaziz A Al-Quorain, Fahad A Al-Muhanna, Stanley Piotrowski, Ezzeddin A Kurdi, Chittibabu Vatte, Ahmed A Alquorain, Noorah H Alfaraj, Abdulaziz M Alrezuk, Fred L Robinson, Alexa K Dowdell, Turki A Alamri, Lauren Hamilton, Hetal Lad, Hui Gao, Divya Gandla, Brendan J Keating, Ryan Meng, Brian D. Piening, and Amein K Al-Ali

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Perspectives in Melanoma: meeting report from the Melanoma Bridge (December 1st-3rd, 2022-Naples, Italy)., Paolo A Ascierto, Sanjiv S Agarwala, Allison Betof Warner, Marc S Ernstoff, Bernard A Fox, Thomas F Gajewski, Jérôme Galon, Claus Garbe, Brian R Gastman, Jeffrey E Gershenwald, Pawel Kalinski, Michelle Krogsgaard, Rom S Leidner, Roger S Lo, Alexander M Menzies, Olivier Michielin, Poulikos I Poulikakos, Jeffrey S Weber, Corrado Caracò, Iman Osman, Igor Puzanov, and Magdalena Thurin

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The "Great Debate" at Immunotherapy Bridge 2022, Naples, November 30th-December 1st, 2022., Paolo A Ascierto, Renier Brentjens, Samir N Khleif, Kunle Odunsi, Katayoun Rezvani, Marco Ruella, Ryan J Sullivan, Bernard A Fox, and Igor Puzanov

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Nivolumab and Relatlimab in Patients With Advanced Melanoma That Had Progressed on Anti-Programmed Death-1/Programmed Death Ligand 1 Therapy: Results From the Phase I/IIa RELATIVITY-020 Trial., Paolo Antonio Ascierto, Evan J Lipson, Reinhard Dummer, James Larkin, Georgina V Long, Rachel E Sanborn, Vanna Chiarion-Sileni, Brigitte Dréno, Stéphane Dalle, Dirk Schadendorf, Margaret K Callahan, Marta Nyakas, Victoria Atkinson, Carlos Alberto Gomez-Roca, Naoya Yamazaki, Hussein A Tawbi, Naomey Sarkis, Deepti Warad, Sonia Dolfi, Priyam Mitra, Satyendra Suryawanshi, and Jean-Jacques Grob

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Rare presence of Charcot-Leyden crystals in acute myeloid leukemia., Sujan Badal, Mahnoosh Taheri, Peter Jiang, and Kirstine Oh

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An expanded safety/feasibility study of the EMulate Therapeutics Voyager™ System in patients with recurrent glioblastoma., Garni Barkhoudarian, Michael Badruddoja, Nicholas Blondin, Sajeel Chowdhary, Charles Cobbs, Julius Paul Duic, John Paul Flores, Ekokobe Fonkem, Edward McClay, Louis Burt Nabors, Michael Salacz, Lynn Taylor, Brian Vaillant, Jaya Gill, and Santosh Kesari

A phase 1 study of AGEN2373, a novel CD137 agonist antibody designed to avoid hepatoxicity, in patients with advanced solid tumors, MA Barve, MH Taylor, and See all authors in comments

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Early Utilization of Mechanical Circulatory Support in Acute Myocardial Infarction Complicated by Cardiogenic Shock: The National Cardiogenic Shock Initiative., Mir B Basir, Alejandro Lemor, Sarah Gorgis, Kirit C Patel, Brian C Kolski, Aditya S Bharadwaj, Joshua W Todd, Behnam N Tehrani, Alexander G Truesdell, David M Lasorda, Thomas A Lalonde, Amir Kaki, Theodore L Schrieber, Nainesh C Patel, Shaun R Senter, Joseph L Gelormini, Steven P Marso, Ayaz M Rahman, Robert E Federici, Charles E Wilkins, A Thomas McRae, Ali Nsair, Christopher P Caputo, Matheen A Khuddus, Juan J Chahin, Allison G Dupont, Andrew M Goldsweig, Michael J Lim, Navin K Kapur, David H W Wohns, Yueren Zhou, Michael J Hacala, and William W O'Neill

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Health-care expenditures are less for minimally invasive than open colectomy for colon cancer: A US commercial claims database analysis., Amir L Bastawrous, I-Fan Shih, Yanli Li, Marissa Khalil, Biruk Almaz, and Robert K Cleary

Cancer Immunotherapy 102, RB Bell

Enhancing Anti-tumor Immunity for the Treatment of Head and Neck Cancer, RB Bell

Enhancing Anti-tumor Immunity for the Treatment of Head and Neck Cancer, RB Bell

Neoadjuvant Immunoradiotherapy Prior to Surgery: Towards a New Paradigm in the Management of Locally Advanced Head and Neck Cancer, RB Bell

State of the Art of Head and Neck Cancer Immunotherapy Translational Research, RB Bell

Transforming Treatment Approaches in Head and Neck Cancer: The Potential of Immunotherapy in Neoadjuvant, Adjuvant and Metastatic Disease, RB Bell

Development and optimization of a broad hyperplex immunofluorescence assay for tumor immune microenvironment characterization, R Ben-Shimol, Carlo Bifulco, Brian Piening, and See full list of authors in comments

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Randomized open-label controlled study of cancer vaccine OSE2101 versus chemotherapy in HLA-A2-positive patients with advanced non-small-cell lung cancer with resistance to immunotherapy: ATALANTE-1., B Besse, E Felip, R Garcia Campelo, M Cobo, C Mascaux, A Madroszyk, F Cappuzzo, W Hilgers, G Romano, F Denis, S Viteri, D Debieuvre, D Galetta, E Baldini, M Razaq, G Robinet, M Maio, A Delmonte, B Roch, P Masson, W Schuette, A Zer, J Remon, D Costantini, B Vasseur, R Dziadziuszko, G Giaccone, ATALANTE-1 study group, and Rachel E Sanborn (ATALANTE-1 study group)

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A Rare Case of Demodicosis Following Treatment With Oral Fluconazole., Joshua A Bezecny, Emily Bolton, Matthew H Taylor, and Elizabeth G Berry

Biomarker Testing, C Bifulco

Empowering Precision Medicine With Genomics, Multi-Modal AI And Real-World Data, C Bifulco

Spatial Biology: Driving Clinical Trials and Diagnostics in a Multiomics AI-Powered Era, C Bifulco

Spatial Omics: an Evolutionary Prospective, C Bifulco

The overview of Spatial Technologies in the use of Immunopathology, C Bifulco

Transforming Patient Care Through Data and AI, C Bifulco

Spatial Biology as a Tool to reveal Mechanisms of Immune Exclusion, Carlo Bifulco

Spatial Biology in a Multiomics AI-Powered Era, Carlo Bifulco

Spatial Omics in Immunotherapy Trials: Unpacking the Challenges, Carlo Bifulco

Implementing CGP plus HRD testing In-house in a Large US Healthcare System, Carlo Bifulco and Brian Piening

A phase 1, open-label, dose escalation and dose expansion study to evaluate the safety, tolerability, pharmacokinetics, and antitumor activity of PF-07799933 (ARRY-440) as a single agent and in combination therapy in participants 16 years and older with advanced solid tumors with BRAF alterations, JTT Black, MH Taylor, and See all authors in comments

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Doubling down on the future of gynecologic oncology: The SGO future of the profession summit report., Stephanie V Blank, Warner K Huh, Maria Bell, Sarah Dilley, Melissa Hardesty, Ebony R Hoskins, Jason Lachance, Fernanda Musa, Emily Prendergast, B J Rimel, Mark Shahin, and Fidel Valea

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Botensilimab, a novel innate/adaptive immune activator, plus balstilimab (anti-PD-1) in patients with recurrent platinum refractory/resistant ovarian cancer (041), Bruno Bockorny, Steven O'Day, Kim Margolin, Rachel E Sanborn, Timothy S Kristedja, and See all authors in comments

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spongEffects: ceRNA modules offer patient-specific insights into the miRNA regulatory landscape., Fabio Boniolo, Markus Hoffmann, Norman Roggendorf, Bahar Tercan, Jan Baumbach, Mauro A A Castro, A Gordon Robertson, Dieter Saur, and Markus List

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ASO Visual Abstract: Changes in Surgical Management of the Axilla Over 11 Years-Report on Over 1500 Breast Cancer Patients Treated with Neoadjuvant Chemotherapy on the Prospective I-SPY2 Trial., Judy C Boughey, Hongmei Yu, Catherine Lu Dugan, Mara A Piltin, Lauren Postlewait, Jennifer D Son, Kirsten K Edmiston, Constantine Godellas, Marie C Lee, Michael J Carr, Jennifer E Tonneson, Angelena Crown, Rachel B Lancaster, Hannah E Woriax, Cheryl A Ewing, Harrison S Chau, Anne K Patterson, Jasmine M Wong, Michael D Alvarado, Rachel L Yang, Theresa W Chan, Jori B Sheade, Gretchen M Ahrendt, Kelsey E Larson, Kayla Switalla, Todd M Tuttle, Julia C Tchou, Roshni Rao, Nina Tamirisa, Puneet Singh, Rebekah E Gould, Alicia Terando, Candice Sauder, Kelly Hewitt, Akiko Chiba, Laura J Esserman, and Rita Mukhtar

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Changes in Surgical Management of the Axilla Over 11 Years - Report on More Than 1500 Breast Cancer Patients Treated with Neoadjuvant Chemotherapy on the Prospective I-SPY2 Trial., Judy C Boughey, Hongmei Yu, Catherine Lu Dugan, Mara A Piltin, Lauren Postlewait, Jennifer D Son, Kirsten K Edmiston, Constantine V Godellas, Marie C Lee, Michael J Carr, Jennifer E Tonneson, Angelena Crown, Rachel B Lancaster, Hannah E Woriax, Cheryl A Ewing, Harrison S Chau, Anne K Patterson, Jasmine M Wong, Michael D Alvarado, Rachel L Yang, Theresa W Chan, Jori B Sheade, Gretchen M Ahrendt, Kelsey E Larson, Kayla Switalla, Todd M Tuttle, Julia C Tchou, Roshni Rao, Nina Tamirisa, Puneet Singh, Rebekah E Gould, Alicia Terando, Candice Sauder, Kelly Hewitt, Akiko Chiba, Laura J Esserman, and Rita A Mukhtar

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Phase I trial of intravenous fenretinide (4-HPR) plus safingol in advanced malignancies., Alexis C Boulter, Barry J Maurer, Meredith Pogue, Min H Kang, Hwangeui Cho, Amanda Knight, C Patrick Reynolds, Donald Quick, Sanjay Awasthi, and David E Gerber

Results from an expanded phase 1 trial of botensilimab, a multifunctional anti-CTLA-4, plus balstilimab (anti-PD-1) for metastatic heavily pretreated microsatellite stable colorectal cancer, AJ Bullock, RE Sanborn, and See all authors in comments

Lucchesi O, Ruete MC, Mayorga LS, and Tomes CN, MA Bustos

The 16th International Congress of the Society for Melanoma Research (SMR), November 20-23, 2019, MA Bustos

Diagnostic cell-free miRNA Signatures Found in Plasma and Urine of Sporadic Renal Cell Carcinoma Patients, MA Bustos, J Gottlieb, R Suyeon, WM Allen, DL Krasne, TG Wilson, JA Linehan, and DSB Hoon

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Diagnostic miRNA Signatures in Paired Tumor, Plasma, and Urine Specimens From Renal Cell Carcinoma Patients., Matias A Bustos, Josh Gottlieb, Jane Choe, Suyeon Ryu, Selena Y Lin, Warren M Allen, David L Krasne, Timothy G Wilson, Dave S B Hoon, and Jennifer M Linehan

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MiR-181a targets STING to drive PARP inhibitor resistance in BRCA- mutated triple-negative breast cancer and ovarian cancer., Matias A Bustos, Takamichi Yokoe, Yoshiaki Shoji, Yuta Kobayashi, Shodai Mizuno, Tomoko Yamazaki, Xiaoqing Zhang, Sreeja C Sekhar, SooMin Kim, Suyeon Ryu, Matthew Knarr, Steven A Vasilev, Analisa DiFeo, Ronny Drapkin, and Dave Hoon

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Incorporating radioligand therapy in clinical practice in the United States for patients with prostate cancer., Jeremie Calais, Stephen M Eulau, Linda Gardner, Ralph J Hauke, Ayse T Kendi, Neal D Shore, and Song Zhao

Temsirolimus (T) in patients (pts) with solid tumors with PIK3CA mutation (mut): Results from the Targeted Agent and Profiling Utilization Registry (TAPUR) study, CJ Calfa, WJ Urba, and See all authors in comments

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Clinical Best Practices for Radiation Safety During Lutetium-177 Therapy., Derek John Cappon, Susanna Fang, Kendall Berry, Gina Capone, Gina L Carlton, Mario Chrétien, John Gough, Jacob Kamen, Anne Khoorshed, Andy Miller, Stephen Nelli, M Peter Petric, Frank Tourneur, and Josip J Zic

Minimal residual disease by circulating tumor DNA as a biomarker of recurrence free survival in resected high-risk melanoma patients treated with mRNA-4157/V940, a personalized cancer vaccine, and pembrolizumab, Matteo S. Carlino, Matthew H. Taylor, and See all authors in comments

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CT275 / 15 - Phase 1 clinical update of allogeneic invariant natural killer T cells (iNKTs), agenT-797, alone or in combination with pembrolizumab or nivolumab in patients with advanced solid tumors, B Carneiro

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CT275 / 15 - Phase 1 clinical update of allogeneic invariant natural killer T cells (iNKTs), agenT-797, alone or in combination with pembrolizumab or nivolumab in patients with advanced solid tumors, B Carneiro, Rachel E Sanborn, and See full list of authors in comments

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New Technology for the Breast Surgeon., Michele Carpenter and Julie Le

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Partial or radical nephrectomy for complex renal mass: a comparative analysis of oncological outcomes and complications from the ROSULA (Robotic Surgery for Large Renal Mass) Collaborative Group., Clara Cerrato, Devin Patel, Riccardo Autorino, Giuseppe Simone, Bo Yang, Robert Uzzo, Francesco Porpiglia, Umberto Capitanio, James Porter, Alp Tuna Beksac, Andrea Minervini, Alessandro Antonelli, Maria Angela Cerruto, Clayton Lau, Akbar Ashrafi, Daniel Eun, Alexandre Mottrie, Carmen Mir, Margaret F Meagher, Dhruv Puri, Mimi Nguyen, Sohail Dhanji, Franklin Liu, Savio D Pandolfo, Alexander Kutikov, Francesco Montorsi, Inderbir S Gill, Chandru Sundaram, Jihad Kaouk, and Ithaar H Derweesh

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Safety and Efficacy Outcomes From a Single-Center Study of Image-Guided Percutaneous Microwave Ablation for Primary and Metastatic Lung Malignancy., Stephen M Chan, Peter J Julien, Peter Kaganjo, Robert McKenna, Charles Forscher, Ronald Natale, Robert N Wolfe, Kristi Butenschoen, Rene J Siegel, and James Mirocha

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Secondary Breast Angiosarcoma After a Primary Diagnosis of Breast Cancer: A Retrospective Analysis of the Surveillance, Epidemiology, and End Results (SEER) Database., Bonny Chau, Elizabeth T Loggers, Lee D Cranmer, Harveshp Mogal, Jeremy M Sharib, Edward Y Kim, Stephanie K Schaub, Kelly G Paulson, Hannah M Linden, Jennifer M Specht, Janice N Kim, Sara H Javid, and Michael J Wagner

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A heterodimer of α and β hemoglobin chains functions as an innate anticancer agent., Maharrish Chelladurai, Dan Xu, Sivan Izraely, Shlomit Ben-Menachem, Roman Bengaiev, Orit Sagi-Assif, Weirong Yuan, Metsada Pasmanik Chor, Dave S Hoon, Wuyuan Lu, and Isaac P Witz