Down syndrome associated moyamoya may worsen epilepsy control and can benefit from surgical revascularization.

Authors

Sarah R Garson, Swedish Epilepsy Center, Seattle, WA, USA.Follow
Stephen J Monteith, Swedish Neuroscience Institute, Department of Neurosurgery, Seattle, WA, USA.Follow
Sheila D Smith, Swedish Neuroscience Institute, Department of Neurology, Seattle, WA, USA.Follow
Bart P Keogh
Ryder P Gwinn, Swedish Neuroscience Institute, Department of Neurosurgery, Seattle, WA, USA; Swedish Neuroscience Institute, Department of Neurology, Seattle, WA, USA.Follow
Michael J Doherty, Swedish Epilepsy Center, Seattle, WA, USA; Swedish Neuroscience Institute, Department of Neurology, Seattle, WA, USA.Follow

Document Type

Article

Publication Date

1-1-2019

Publication Title

Epilepsy Behav Case Rep

Keywords

Bypass; Perfusion; Stenosis

Abstract

Objectives: To examine outcome of bilateral extracranial to intracranial (EC-IC) bypass surgeries for a Down syndrome patient with hard-to-treat epilepsy and moyamoya.

Materials and methods: Superficial temporal arteries were anastamosed using an indirect bypass technique to middle cerebral arteries bilaterally to help limit perfusion deficits and seizure controls.

Results: Two superficial temporal to middle cerebral artery indirect bypass surgeries were performed within 3 months. Post-revascularization improvements included seizure control, gait, perfusion, wakefulness, language and quality of life.

Conclusion: In patients with Down syndrome and moyamoya, improvements in seizure control and quality of life may occur with EC-IC bypass procedures.

Clinical Institute

Neurosciences (Brain & Spine)

Department

Neurosciences

Department

Surgery

Recommended Citation

Garson, Sarah R; Monteith, Stephen J; Smith, Sheila D; Keogh, Bart P; Gwinn, Ryder P; and Doherty, Michael J, "Down syndrome associated moyamoya may worsen epilepsy control and can benefit from surgical revascularization." (2019). Articles, Abstracts, and Reports. 902.
https://digitalcommons.providence.org/publications/902