Document Type
Article
Publication Date
1-1-2019
Publication Title
RMD Open
Keywords
adherence; ankylosing spondylitis; disease-modifying antirheumatic drugs; psoriatic arthritis; rheumatoid arthritis
Abstract
Objective: This analysis explored the association of treatment adherence with beliefs about medication, patient demographic and disease characteristics and medication types in rheumatoid arthritis (RA), psoriatic arthritis (PsA) or ankylosing spondylitis (AS) to develop adherence prediction models.
Methods: The population was a subset from ALIGN, a multicountry, cross-sectional, self-administered survey study in adult patients (n=7328) with six immune-mediated inflammatory diseases who were routinely receiving systemic therapy. Instruments included Beliefs about Medicines Questionnaire (BMQ) and 4-item Morisky Medication Adherence Scale (MMAS-4
Results: A total of 3390 rheumatological patients were analysed (RA, n=1943; PsA, n=635; AS, n=812). Based on the strongest significant associations, the adherence prediction models included type of treatment, age, race (RA and AS) or disease duration (PsA) and medication beliefs (RA and PsA, BMQ-General
Conclusions: For the first time, simple medication adherence prediction models for patients with RA, PsA and AS are available, which may help identify patients at high risk of non-adherence to systemic therapies.
Trial registration number: ACTRN12612000977875.
Clinical Institute
Orthopedics & Sports Medicine
Department
Rheumatology
Department
Orthopedics
Recommended Citation
Smolen, Josef S; Gladman, Dafna; McNeil, H Patrick; Mease, Philip J; Sieper, Joachim; Hojnik, Maja; Nurwakagari, Pascal; and Weinman, John, "Predicting adherence to therapy in rheumatoid arthritis, psoriatic arthritis or ankylosing spondylitis: a large cross-sectional study." (2019). Articles, Abstracts, and Reports. 1188.
https://digitalcommons.providence.org/publications/1188
